Slc27a4 | ENSMUSG00000059316 | NCBI 26569

Details for: Slc27a4

Gene ID: 26569

Symbol: Slc27a4

Ensembl ID: ENSMUSG00000059316

Description: solute carrier family 27 (fatty acid transporter), member 4

Associated with

Slc-mediated transmembrane transport
(R-MMU-425407)
Transport of fatty acids
(R-MMU-804914)
Transport of small molecules
(R-MMU-382551)
Transport of vitamins, nucleosides, and related molecules
(R-MMU-425397)
Activation of gtpase activity
(GO:0090630)
Arachidonate-coa ligase activity
(GO:0047676)
Brush border membrane
(GO:0031526)
Endoplasmic reticulum
(GO:0005783)
Endoplasmic reticulum membrane
(GO:0005789)
Establishment of localization in cell
(GO:0051649)
Fatty acid metabolic process
(GO:0006631)
Fatty acid transport
(GO:0015908)
Glucose import in response to insulin stimulus
(GO:0044381)
Lipid transport across blood-brain barrier
(GO:1990379)
Long-chain fatty acid-coa ligase activity
(GO:0004467)
Long-chain fatty acid import into cell
(GO:0044539)
Long-chain fatty acid metabolic process
(GO:0001676)
Long-chain fatty acid transmembrane transporter activity
(GO:0005324)
Long-chain fatty acid transport
(GO:0015909)
Medium-chain fatty acid transport
(GO:0001579)
Microvillus
(GO:0005902)
Negative regulation of all-trans-retinyl-ester hydrolase, 11-cis retinol forming activity
(GO:0062003)
Negative regulation of insulin receptor signaling pathway
(GO:0046627)
Nucleotide binding
(GO:0000166)
Oleate transmembrane transporter activity
(GO:1901480)
Oleoyl-coa ligase activity
(GO:0090434)
Palmitoyl-coa ligase activity
(GO:0090433)
Plasma membrane
(GO:0005886)
Positive regulation of apoptotic process
(GO:0043065)
Response to nutrient
(GO:0007584)
Skin development
(GO:0043588)
Very long-chain fatty acid-coa ligase activity
(GO:0031957)
Very long-chain fatty acid catabolic process
(GO:0042760)
Very long-chain fatty acid metabolic process
(GO:0000038)

Other Information

Proteins

Arachidonate--CoA ligase

Genular Protein ID: 1511916749

Symbol: S27A4_MOUSE

Name: Arachidonate--CoA ligase

UniProtKB Accession Codes:

Q91VE0 O88562 Q3TD48

Database IDs:

Citations:

PubMed ID: 11404000

Title: Mouse fatty acid transport protein 4 (FATP4): characterization of the gene and functional assessment as a very long chain acyl-CoA synthetase.

PubMed ID: 11404000

DOI: 10.1016/s0378-1119(01)00489-9

PubMed ID: 16141072

Title: The transcriptional landscape of the mammalian genome.

PubMed ID: 16141072

DOI: 10.1126/science.1112014

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 9671728

Title: A family of fatty acid transporters conserved from mycobacterium to man.

PubMed ID: 9671728

DOI: 10.1073/pnas.95.15.8625

PubMed ID: 10518211

Title: Identification of the major intestinal fatty acid transport protein.

PubMed ID: 10518211

DOI: 10.1016/s1097-2765(00)80332-9

PubMed ID: 14512415

Title: Targeted deletion of fatty acid transport protein-4 results in early embryonic lethality.

PubMed ID: 14512415

DOI: 10.1074/jbc.m309759200

PubMed ID: 12821645

Title: Mice with targeted disruption of the fatty acid transport protein 4 (Fatp 4, Slc27a4) gene show features of lethal restrictive dermopathy.

PubMed ID: 12821645

DOI: 10.1083/jcb.200207080

PubMed ID: 12697906

Title: Cloning of wrinkle-free, a previously uncharacterized mouse mutation, reveals crucial roles for fatty acid transport protein 4 in skin and hair development.

PubMed ID: 12697906

DOI: 10.1073/pnas.0431186100

PubMed ID: 15653672

Title: Enzymatic properties of purified murine fatty acid transport protein 4 and analysis of acyl-CoA synthetase activities in tissues from FATP4 null mice.

PubMed ID: 15653672

DOI: 10.1074/jbc.m412629200

PubMed ID: 15699031

Title: Comparative biochemical studies of the murine fatty acid transport proteins (FATP) expressed in yeast.

PubMed ID: 15699031

DOI: 10.1074/jbc.m409598200

PubMed ID: 16452087

Title: Comprehensive identification of phosphorylation sites in postsynaptic density preparations.

PubMed ID: 16452087

DOI: 10.1074/mcp.t500041-mcp200

PubMed ID: 21183079

Title: A tissue-specific atlas of mouse protein phosphorylation and expression.

PubMed ID: 21183079

DOI: 10.1016/j.cell.2010.12.001

PubMed ID: 20448275

Title: Development and validation of a high-throughput screening assay for human long-chain fatty acid transport proteins 4 and 5.

PubMed ID: 20448275

DOI: 10.1177/1087057110369700

PubMed ID: 23407971

Title: Fatty acid transport protein 4 (FATP4) prevents light-induced degeneration of cone and rod photoreceptors by inhibiting RPE65 isomerase.

PubMed ID: 23407971

DOI: 10.1523/jneurosci.2428-12.2013

Sequence Information:

Length: 643
Mass: 72319
Checksum: 10B3E9730FDF586A
Sequence:

MLLGASLVGA LLFSKLVLKL PWTQVGFSLL LLYLGSGGWR FIRVFIKTVR RDIFGGMVLL 
KVKTKVRRYL QERKTVPLLF ASMVQRHPDK TALIFEGTDT HWTFRQLDEY SSSVANFLQA 
RGLASGNVVA LFMENRNEFV GLWLGMAKLG VEAALINTNL RRDALRHCLD TSKARALIFG 
SEMASAICEI HASLEPTLSL FCSGSWEPST VPVSTEHLDP LLEDAPKHLP SHPDKGFTDK 
LFYIYTSGTT GLPKAAIVVH SRYYRMASLV YYGFRMRPDD IVYDCLPLYH SAGNIVGIGQ 
CLLHGMTVVI RKKFSASRFW DDCIKYNCTI VQYIGELCRY LLNQPPREAE SRHKVRMALG 
NGLRQSIWTD FSSRFHIPQV AEFYGATECN CSLGNFDSRV GACGFNSRIL SFVYPIRLVR 
VNEDTMELIR GPDGVCIPCQ PGQPGQLVGR IIQQDPLRRF DGYLNQGANN KKIANDVFKK 
GDQAYLTGDV LVMDELGYLY FRDRTGDTFR WKGENVSTTE VEGTLSRLLH MADVAVYGVE 
VPGTEGRAGM AAVASPISNC DLESFAQTLK KELPLYARPI FLRFLPELHK TGTFKFQKTE 
LRKEGFDPSV VKDPLFYLDA RKGCYVALDQ EAYTRIQAGE EKL

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: Slc27a4

Associated with

Other Information

Mouse fatty acid transport protein 4 (FATP4): characterization of the gene and functional assessment as a very long chain acyl-CoA synthetase. PubMed ID: 11404000

The transcriptional landscape of the mammalian genome. PubMed ID: 16141072

The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). PubMed ID: 15489334

A family of fatty acid transporters conserved from mycobacterium to man. PubMed ID: 9671728

Identification of the major intestinal fatty acid transport protein. PubMed ID: 10518211

Targeted deletion of fatty acid transport protein-4 results in early embryonic lethality. PubMed ID: 14512415

Mice with targeted disruption of the fatty acid transport protein 4 (Fatp 4, Slc27a4) gene show features of lethal restrictive dermopathy. PubMed ID: 12821645

Cloning of wrinkle-free, a previously uncharacterized mouse mutation, reveals crucial roles for fatty acid transport protein 4 in skin and hair development. PubMed ID: 12697906

Enzymatic properties of purified murine fatty acid transport protein 4 and analysis of acyl-CoA synthetase activities in tissues from FATP4 null mice. PubMed ID: 15653672

Comparative biochemical studies of the murine fatty acid transport proteins (FATP) expressed in yeast. PubMed ID: 15699031

Comprehensive identification of phosphorylation sites in postsynaptic density preparations. PubMed ID: 16452087

A tissue-specific atlas of mouse protein phosphorylation and expression. PubMed ID: 21183079

Development and validation of a high-throughput screening assay for human long-chain fatty acid transport proteins 4 and 5. PubMed ID: 20448275

Fatty acid transport protein 4 (FATP4) prevents light-induced degeneration of cone and rod photoreceptors by inhibiting RPE65 isomerase. PubMed ID: 23407971