Abcd2 | ENSMUSG00000055782 | NCBI 26874

Details for: Abcd2

Gene ID: 26874

Symbol: Abcd2

Ensembl ID: ENSMUSG00000055782

Description: ATP-binding cassette, sub-family D member 2

Associated with

Abc-family proteins mediated transport
(R-MMU-382556)
Abc transporters in lipid homeostasis
(R-MMU-1369062)
Class i peroxisomal membrane protein import
(R-MMU-9603798)
Protein localization
(R-MMU-9609507)
Transport of small molecules
(R-MMU-382551)
Abc-type transporter activity
(GO:0140359)
Atpase-coupled transmembrane transporter activity
(GO:0042626)
Atp binding
(GO:0005524)
Atp hydrolysis activity
(GO:0016887)
Fatty acid beta-oxidation
(GO:0006635)
Fatty acyl-coa hydrolase activity
(GO:0047617)
Long-chain fatty acid import into peroxisome
(GO:0015910)
Long-chain fatty acid transmembrane transporter activity
(GO:0005324)
Mitochondrion
(GO:0005739)
Myelin maintenance
(GO:0043217)
Negative regulation of cytokine production involved in inflammatory response
(GO:1900016)
Negative regulation of reactive oxygen species biosynthetic process
(GO:1903427)
Neuron projection maintenance
(GO:1990535)
Peroxisomal membrane
(GO:0005778)
Peroxisome
(GO:0005777)
Peroxisome organization
(GO:0007031)
Positive regulation of fatty acid beta-oxidation
(GO:0032000)
Positive regulation of unsaturated fatty acid biosynthetic process
(GO:2001280)
Protein binding
(GO:0005515)
Protein heterodimerization activity
(GO:0046982)
Protein homodimerization activity
(GO:0042803)
Response to bacterium
(GO:0009617)
Transmembrane transport
(GO:0055085)
Very long-chain fatty acid catabolic process
(GO:0042760)
Very long-chain fatty acid metabolic process
(GO:0000038)

Other Information

Proteins

ATP-binding cassette sub-family D member 2

Genular Protein ID: 3861942268

Symbol: ABCD2_MOUSE

Name: ATP-binding cassette sub-family D member 2

UniProtKB Accession Codes:

Q61285 A0A0R4J0U5 Q8BQ63 Q8C4B6

Database IDs:

Citations:

PubMed ID: 8577752

Title: A close relative of the adrenoleukodystrophy (ALD) gene codes for a peroxisomal protein with a specific expression pattern.

PubMed ID: 8577752

DOI: 10.1073/pnas.93.3.1265

PubMed ID: 16141072

Title: The transcriptional landscape of the mammalian genome.

PubMed ID: 16141072

DOI: 10.1126/science.1112014

PubMed ID: 19468303

Title: Lineage-specific biology revealed by a finished genome assembly of the mouse.

PubMed ID: 19468303

DOI: 10.1371/journal.pbio.1000112

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 17208939

Title: Mitochondrial phosphoproteome revealed by an improved IMAC method and MS/MS/MS.

PubMed ID: 17208939

DOI: 10.1074/mcp.m600218-mcp200

PubMed ID: 21183079

Title: A tissue-specific atlas of mouse protein phosphorylation and expression.

PubMed ID: 21183079

DOI: 10.1016/j.cell.2010.12.001

PubMed ID: 16223892

Title: Inactivation of the peroxisomal ABCD2 transporter in the mouse leads to late-onset ataxia involving mitochondria, Golgi and endoplasmic reticulum damage.

PubMed ID: 16223892

DOI: 10.1093/hmg/ddi384

PubMed ID: 18854420

Title: A key role for the peroxisomal ABCD2 transporter in fatty acid homeostasis.

PubMed ID: 18854420

DOI: 10.1152/ajpendo.90736.2008

Sequence Information:

Length: 741
Mass: 83457
Checksum: 24B9952F61AB49D9
Sequence:

MIHMLNAAAY RVKWTRSGAA KRAACLVAAA YALKTLYPII GKRLKQPGHR KAKAEAYSPA 
ENREILHCTE IICKKPAPGL NAAFFKQLLE LRKILFPKLV TTETGWLCLH SVALISRTFL 
SIYVAGLDGK IVKSIVEKKP RTFIIKLIKW LMIAIPATFV NSAIRYLECK LALAFRTRLV 
DHAYETYFAN QTYYKVINMD GRLANPDQSL TEDIMMFSQS VAHLYSNLTK PILDVILTSY 
TLIRTATSRG ASPIGPTLLA GLVVYATAKV LKACSPKFGS LVAEEAHRKG YLRYVHSRII 
ANVEEIAFYR GHKVEMKQLQ KCYKALAYQM NLILSKRLWY IMIEQFLMKY VWSSCGLIMV 
AIPIITATGF ADGDLEDGPK QAMVSDRTEA FTTARNLLAS GADAIERIMS SYKEITELAG 
YTARVYNMFW VFDEVKRGIY KRTVTQEPEN HSKRGGNLEL PLSDTLAIKG TVIDVDHGII 
CENVPIITPA GEVVASRLNF KVEEGMHLLI TGPNGCGKSS LFRILSGLWP VYEGVLYKPP 
PQHMFYIPQR PYMSLGSLRD QVIYPDSADD MREKGYTDQD LERILHSVHL YHIVQREGGW 
DAVMDWKDVL SGGEKQRMGM ARMFYHKPKY ALLDECTSAV SIDVEGKIFQ AAIGAGISLL 
SITHRPSLWK YHTHLLQFDG EGGWRFEQLD TAIRLTLSEE KQKLESQLAG IPKMQQRLNE 
LCKILGEDSV LKTIQTAEKT S

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: Abcd2

Associated with

Other Information

A close relative of the adrenoleukodystrophy (ALD) gene codes for a peroxisomal protein with a specific expression pattern. PubMed ID: 8577752

The transcriptional landscape of the mammalian genome. PubMed ID: 16141072

Lineage-specific biology revealed by a finished genome assembly of the mouse. PubMed ID: 19468303

The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). PubMed ID: 15489334

Mitochondrial phosphoproteome revealed by an improved IMAC method and MS/MS/MS. PubMed ID: 17208939

A tissue-specific atlas of mouse protein phosphorylation and expression. PubMed ID: 21183079

Inactivation of the peroxisomal ABCD2 transporter in the mouse leads to late-onset ataxia involving mitochondria, Golgi and endoplasmic reticulum damage. PubMed ID: 16223892

A key role for the peroxisomal ABCD2 transporter in fatty acid homeostasis. PubMed ID: 18854420