Details for: Pclo

Gene ID: 26875

Symbol: Pclo

Ensembl ID: ENSMUSG00000061601

Description: piccolo (presynaptic cytomatrix protein)

Associated with

Other Information

Genular Protein ID: 3142794020

Symbol: PCLO_MOUSE

Name: Brain-derived HLMN protein

UniProtKB Accession Codes:

Database IDs:

Citations:

PubMed ID: 10508862

Title: Aczonin, a 550-kd putative scaffolding protein of presynaptic active zones, shares homology regions with rim and bassoon and binds profilin.

PubMed ID: 10508862

DOI: 10.1083/jcb.147.1.151

PubMed ID: 12401793

Title: Piccolo, a Ca2+ sensor in pancreatic beta-cells. Involvement of cAMP-GEFII.Rim2.Piccolo complex in cAMP-dependent exocytosis.

PubMed ID: 12401793

DOI: 10.1074/jbc.m210146200

PubMed ID: 19468303

Title: Lineage-specific biology revealed by a finished genome assembly of the mouse.

PubMed ID: 19468303

DOI: 10.1371/journal.pbio.1000112

PubMed ID: 16452087

Title: Comprehensive identification of phosphorylation sites in postsynaptic density preparations.

PubMed ID: 16452087

DOI: 10.1074/mcp.t500041-mcp200

PubMed ID: 16452088

Title: O-linked N-acetylglucosamine proteomics of postsynaptic density preparations using lectin weak affinity chromatography and mass spectrometry.

PubMed ID: 16452088

DOI: 10.1074/mcp.t500040-mcp200

PubMed ID: 17114649

Title: Qualitative and quantitative analyses of protein phosphorylation in naive and stimulated mouse synaptosomal preparations.

PubMed ID: 17114649

DOI: 10.1074/mcp.m600046-mcp200

PubMed ID: 18034455

Title: Large-scale identification and evolution indexing of tyrosine phosphorylation sites from murine brain.

PubMed ID: 18034455

DOI: 10.1021/pr0701254

PubMed ID: 19812333

Title: A protein interaction node at the neurotransmitter release site: domains of Aczonin/Piccolo, Bassoon, CAST, and rim converge on the N-terminal domain of Munc13-1.

PubMed ID: 19812333

DOI: 10.1523/jneurosci.1255-09.2009

PubMed ID: 21183079

Title: A tissue-specific atlas of mouse protein phosphorylation and expression.

PubMed ID: 21183079

DOI: 10.1016/j.cell.2010.12.001

PubMed ID: 28231469

Title: Bassoon Controls Presynaptic Autophagy through Atg5.

PubMed ID: 28231469

DOI: 10.1016/j.neuron.2017.01.026

Sequence Information:

  • Length: 5068
  • Mass: 550834
  • Checksum: DBF54D47501AC79A
  • Sequence:
  • MGNEASLEGE GLPEGLAAAA GGAGGSGSAL HPGIPAGMEA DLSQLSEEER RQIAAVMSRA 
    QGLPKGSVPA AAAESPSMHR KQELDSSQAP QQPGKPPDPG RPPQHGLSKS RTTDTFRSEQ 
    KLPGRSPSTI SLKESKSRTD FKEEYKSSMM PGFFSDVNPL SAVSSVVNKF NPFDLISDSE 
    AVQEETTKKQ KVAQKDQGKS EGITKPSLQQ PSPKLIPKQQ GPGKEVIPQD IPSKSVSSQQ 
    AEKTKPQAPG TAKPSQQSPA QTPAQQAKPV AQQPGPAKAT VQQPGPAKSP AQPAGTGKSP 
    AQPPVTAKPP AQQAGLEKTS LQQPGPKSLA QTPGQGKVPP GPAKSPAQQP GTAKLPAQQP 
    GPQTAAKVPG PTKTPAQLSG PGKTPAQQPG PTKPSPQQPI PAKPQPQQPV ATKPQPQQPA 
    PAKPQPQHPT PAKPQPQHPT PAKPQPQQPT PAKPQPQQPT PAKPQPQQPT PAKPQPQHPT 
    PAKPQPQQPG LGKPSAQQPS KSISQTVTGR PLQAPPTSAA QAPAQGLSKT ICPLCNTTEL 
    LLHTPEKANF NTCTECQSTV CSLCGFNPNP HLTEIKEWLC LNCQMQRALG GELAAIPSSP 
    QPTPKAASVQ PATASKSPVP SQQASPKKEL PSKQDSPKAP ESKKPPPLVK QPTLHGPTPA 
    TAPQPPVAEA LPKPAPPKKP SAALPEQAKA PVADVEPKQP KTTETLTDSP SSAAATSKPA 
    ILSSQVQAQA QVTTAPPLKT DSAKTSQSFP PTGDTITPLD SKAMPRPASD SKIVSHPGPT 
    SESKDPVQKK EEPKKAQTKV TPKPDTKPVP KGSPTPSGTR PTTGQATPQS QQPPKPPEQS 
    RRFSLNLGGI ADAPKSQPTT PQETVTGKLF GFGASIFSQA SNLISTAGQQ APHPQTGPAA 
    PSKQAPPPSQ TLAAQGPPKS TGPHPSAPAK TTAVKKETKG PAAENLEAKP VQAPTVKKAE 
    KDKKPPPGKV SKPPPTEPEK AVLAQKPDKT TKPKPACPLC RTELNVGSQD PPNFNTCTEC 
    KNQVCNLCGF NPTPHLTEIQ EWLCLNCQTQ RAISGQLGDM DKMPPASSGP KASPVPAPAE 
    PPPQKTPTAA HAKGKKKETE VKAETEKQIP EKETPSIEKT PPAVATDQKL EESEVTKSLV 
    SVLPEKKPSE EEKALPADKK EKKPPAAEAP PLEEKKPIPD DQKLPPDAKP SASEGEEKRD 
    LLKAHVQIPE EGPIGKVASL ACEGEQQPDT RPEDLPGATP QTLPKDRQKE SRDVTQPQAE 
    GTAKEGRGEP SKDRTEKEED KSDTSSSQQP KSPQGLSDTG YSSDGISGSL GEIPSLIPSD 
    EKDLLKGLKK DSFSQESSPS SPSDLAKLES TVLSILEAQA STLVGEKAEK KTQPQKVSPE 
    QPQDQQKTQT PSETRDISIS EEEIKESQEK KVTSKKDSAQ GFPSRKEHKE NPELVDDLSP 
    RRASYDSVED SSESENSPVA RRKRRTSIGS SSSEEYKQED SQGSGEDEDF IRKQIIEMSA 
    DEDASGSEDE EFIRSQLKEI GGVTESQKRE ETKGKGKSPA GKHRRLTRKS STSFDDDAGR 
    RHSWHDEDDE TFDESPELKF RETKSQESEE LVVAGGGGLR RFKTIELNST VTDKYSAESS 
    QKKTTLYFDE EPELEMESLT DSPEDRSRGE GSSSLHASSF TPGTSPTSVS SLDEDSDSSP 
    SHKKGESKQQ RKARHRSHGP LLPTIEDSSE EEELREEEEL LKEQEKQREL EQQQRKSSSK 
    KSKKDKDELR AQRRRERPKT PPSNLSPIED ASPTEELRQA AEMEELHRSS CSEYSPSIES 
    DPEGFEISPE KIIEVQKVYK LPTAVSLYSP TDEQSVMQKE GAQKALKSAE EMYEEMMHKP 
    HKYKAFPAAN ERDEVFEKEP LYGGMLIEDY IYESLVEDTY NGSVDGSLLT RQDEQNGFMQ 
    QRGREQKIRL QEQIYDDPMQ KITDLQKEFY ELESLHSIVP QEDIVSSSYI IPESHEIVDL 
    GSMVTSTSEE KKLLDADAAY EELMKRQQMQ VTDGSSLIQT TMGDDMAEST LDFDRVQDAS 
    LTSSILSGAS LTDSTSSATL SIPDVKITQH FSTEEFEDEY VTDYTREIQE IIAHESLILT 
    YSEPSESATS VPPSDTPSLT SSISSVCTTD SSSPVTTLDS LTTVYTEPAD VITKFKDSEE 
    ISSTYFPGSV IDYPEDIGVS LDRTITPESR TNADQIMISF PGIAPSITES VATKPERPQA 
    DTISTDLPIS EKELIKGKKE TGDGIILEVL DAYKDKREES EAELTKISLP ETGLAPTPSS 
    QTKEQPGSPH SVSGEILGQE KPTYRSPSGG LPVSTHPSKS HPFFRSSSLD ISAQPPPPPP 
    PPPPPPPPPP PPPPPPLPPA TSPKPPTYPK RKLAAAAPVA PTAIVTAHAD AIPTVEATAA 
    RRSNGLPATK ICAAAPPPVP PKPSSIPTGL VFTHRPEASK PPIAPKPAVP EIPVTTQKTT 
    DTCPKPTGLP LTSNMSLNLV TSADYKLPSP TSPLSPHSNK SSPRYSKSLM ETYVVITLPS 
    EPGTPTDSSA AQAITSWPLG SPPKDLVSLE TVFSVVPPMT STEIPSASQP TLYTSGALGT 
    FSVTPAVTAS LFQTVPTSLT QFLPAEASKP EVSAVSSAVP SVAPRSVSIP IPPEPLALDR 
    HQYKENGKLP LIGDAIDLRT IPKSEVKVTE KCMDLSASAM DVKRQTTANE VYRRQISAVQ 
    PSIINLSAAS SLGTPVTMDS KTVAVVTCTD TTIYTTGTES QVGIEHAVTS PLQLTTSKHT 
    ELQYRKPSSQ AFPMIRDEAP INLSLGPSTQ AVTLAVTKPV TVPPVGVTNG WTDSTISQGI 
    TDGEVVDLST SKSHRTVVTM DESTSNVVTK IIEDEEKPVD LTAGRRAVCC DMVYKLPFGR 
    SCTAQQPATT LPEDRFGYRD DHYQYDRSGP YGYRGIGGMK PSMSDTNLAE AGHFFYKSKN 
    AFDYSGGTEA AVDLTSGRVS TGEVMDYSSK TTGPYPETRQ VISGVGISTP QYSTARMTPP 
    PGPQYGVGSV LRSSNGVVYS SVATPIPSTF AITTQPGSIF STTVRDLSGI HTTDAITSLS 
    ALHQSQPMPR SYFITTGASE TDISVTSIDI NASLQTITME TLPAETMDSV PTLTTASEVF 
    SEVVGEESTL LIVPDEDKQQ QQLDLERELL ELEKIKQQRF AEELEWERQE IQRFREQEKI 
    MVQKKLEELQ SMKQHLLYQQ EEERQAQFMM RQETLAQQQL QLEQIQQLQQ QLHQQLEEQK 
    LRQIYQYNYE PSGTASPQTT TEQAILEGQY VATEGSQFWA TEDATTTAST VVAIEIPQSQ 
    GWYTVQSDGV TQYIAPPGIL STVSEIPLTD VVVKEEKQPK KRSSGAKVRG QYDEMGESMA 
    DDPRNLKKIV DSGVQTDDEE TADRTYASRR RRTKKSVDTS VQTDDEDQDE WDMPSRSRRK 
    ARTGKYGDST AEGDKTKPPS KVSSVAVQTV AEISVQTEPL GTIRTPSIRA RVDAKVEIIK 
    HISAPEKTYK GGSLGCQTET DPDTQSPPYM GATSPPKDKK RPTPLEIGYS SSHLRADPTV 
    QLAPSPPKSP KVLYSPISPL SPGHALEPAF VPYEKPLPDD ISPQKVLHPD MAKVPPASPK 
    TAKMMQRSMS DPKPLSPTAD ESSRAPFQYS EGFTAKGSQT TSGTQKKVKR TLPNPPPEEA 
    STGTQSTYST MGTASRRRMC RTNTMARAKI LQDIDRELDL VERESAKLRK KQAELDEEEK 
    EIDAKLRYLE MGINRRKEAL LKEREKRERA YLQGVAEDRD YMSDSEVSST RPSRVESQHG 
    IERPRTAPQT EFSQFIPPQT QTEAQLVPPT SPYTQYQYSS PALPTQAPTP YTQQSHFQQQ 
    TLYHQQVSPY QTQPTFQAVA TMSFTPQAQP TPTPQPSYQL PSQMMVIQQK PRQTTLYLEP 
    KITSTYEVIR NQPLMIAPVS TDNTYAVSHL GSKYNSLDLR IGLEERSSMA SSPISSISAD 
    SFYADIDHHT SRNYVLIDDI GDITKGTAAL SSAFSLHEKD LSKTDRLLRT TETRRSQEVT 
    DFLAPLQTSS RLHSYVKAEE DSMEDPYELK LLKHQIKQEF RRGTESLDHL AGLSHYYHAD 
    TSYRHFPKSE KYSISRLTLE KQAAKQLPAA ILYQKQSKHK KALIDPKMSK FSPIQESRDL 
    EPDYPTYLSS STSSIGGISS RARLLQDDIT FGLRKNITDQ QKFMGSSLGS GLGTLGNTIR 
    SALQDEADKP YSSGSRSRPS SRPSSVYGLD LSIKRDSSSS SLRLKAQEAE ALDVSFGHSS 
    SSARTKPTSL PISQSRGRIP IVAQNSEEES PLSPVGQPMG MARAAAGPLP PISADTRDQF 
    GSSHSLPEVQ QHMREESRTR GYDRDIAFIM DDFQHAMSDS EAYHLRREET DWFDKPRESR 
    LENGHGLDRK LPERLVHSRP LSQHQEQILQ MNGKTMHYIF PHARIKITRD SKDHTVSGNG 
    LGIRIVGGKE IPGHSGEIGA YIAKILPGGS AEHSGKLIEG MQVLEWNGIP LTSKTYEEVQ 
    SIINQQSGEA EICVRLDLNM LSDSENPQHL ELHEPPKVVD KAKSPGVDPK QLAAELQKVS 
    LQQSPLVMSS VVEKGAHAHS GPTSAGSSSV PSPGQPGSPS VSKKKHGGSK PTDVSKTASH 
    PITGEIQLQI NYDLGNLIIH ILQARNLVPR DNNGYSDPFV KVYLLPGRGQ VMVVQNASVE 
    YKRRTKYVQK SLNPEWNQTV IYKSISMEQL MKKTLEVTVW DYDRFSSNDF LGEVLIDLSS 
    TSHLDNTPRW YPLKEQTESI EHGKSHSSQN SQQSPKPSVI KSRSHGIFPD PSKDMQVPTI 
    EKSHSSPGSS KSSSEGHLRS HGPSRSQSKT SVAQTHLEDA GAAIAAAEAA VQQLRIQPTK 
    PTNHRPAETS VSTGSSGSSV GSGYSVDSEG SSCVAGEPNL LPIPRIGKMG QNGQDPVKQP 
    GMGAADTEAK TQVMGEIKLA LKKEMKTDGE QLIVEILQCR NITYKFKSPD HLPDLYVKIY 
    VINIATQKKV IKKKTRVCRH DREPSFNETF RFSLSPAGHS LQILLFSNGG KFMKKTLIGE 
    ACIWLDKVDL RKRIVNWHKL LMSPTQTH

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.