Exo1 | ENSMUSG00000039748 | NCBI 26909

Details for: Exo1

Gene ID: 26909

Symbol: Exo1

Ensembl ID: ENSMUSG00000039748

Description: exonuclease 1

Associated with

Cell cycle
(R-MMU-1640170)
Cell cycle checkpoints
(R-MMU-69620)
Dna double-strand break repair
(R-MMU-5693532)
Dna repair
(R-MMU-73894)
G2/m checkpoints
(R-MMU-69481)
G2/m dna damage checkpoint
(R-MMU-69473)
Gene expression (transcription)
(R-MMU-74160)
Generic transcription pathway
(R-MMU-212436)
Hdr through homologous recombination (hrr)
(R-MMU-5685942)
Hdr through homologous recombination (hrr) or single strand annealing (ssa)
(R-MMU-5693567)
Hdr through single strand annealing (ssa)
(R-MMU-5685938)
Homologous dna pairing and strand exchange
(R-MMU-5693579)
Homology directed repair
(R-MMU-5693538)
Mismatch repair (mmr) directed by msh2:msh6 (mutsalpha)
(R-MMU-5358565)
Presynaptic phase of homologous dna pairing and strand exchange
(R-MMU-5693616)
Processing of dna double-strand break ends
(R-MMU-5693607)
Regulation of tp53 activity
(R-MMU-5633007)
Regulation of tp53 activity through phosphorylation
(R-MMU-6804756)
Resolution of d-loop structures
(R-MMU-5693537)
Resolution of d-loop structures through holliday junction intermediates
(R-MMU-5693568)
Rna polymerase ii transcription
(R-MMU-73857)
Transcriptional regulation by tp53
(R-MMU-3700989)
5'-3' dna exonuclease activity
(GO:0035312)
5'-3' exonuclease activity
(GO:0008409)
5'-flap endonuclease activity
(GO:0017108)
Chromatin binding
(GO:0003682)
Dna binding
(GO:0003677)
Dna recombination
(GO:0006310)
Dna strand resection involved in replication fork processing
(GO:0110025)
Double-stranded dna 5'-3' dna exonuclease activity
(GO:0051908)
Flap endonuclease activity
(GO:0048256)
Humoral immune response mediated by circulating immunoglobulin
(GO:0002455)
Isotype switching
(GO:0045190)
Meiotic cell cycle
(GO:0051321)
Metal ion binding
(GO:0046872)
Mismatch repair
(GO:0006298)
Nuclear body
(GO:0016604)
Nucleobase-containing compound metabolic process
(GO:0006139)
Nucleoplasm
(GO:0005654)
Nucleus
(GO:0005634)
Plasma membrane
(GO:0005886)
Single-stranded dna 5'-3' dna exonuclease activity
(GO:0045145)
Somatic hypermutation of immunoglobulin genes
(GO:0016446)

Other Information

Proteins

Exonuclease 1

Genular Protein ID: 3563653786

Symbol: EXO1_MOUSE

Name: Exonuclease 1

UniProtKB Accession Codes:

Q9QZ11 Q3TLM4 Q923A5

Database IDs:

Citations:

PubMed ID: 10497278

Title: Expression specificity of the mouse exonuclease 1 (mExo1) gene.

PubMed ID: 10497278

DOI: 10.1093/nar/27.20.4114

PubMed ID: 16141072

Title: The transcriptional landscape of the mammalian genome.

PubMed ID: 16141072

DOI: 10.1126/science.1112014

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 12629043

Title: Inactivation of exonuclease 1 in mice results in DNA mismatch repair defects, increased cancer susceptibility, and male and female sterility.

PubMed ID: 12629043

DOI: 10.1101/gad.1060603

PubMed ID: 14716311

Title: Altered somatic hypermutation and reduced class-switch recombination in exonuclease 1-mutant mice.

PubMed ID: 14716311

DOI: 10.1038/ni1031

Sequence Information:

Length: 837
Mass: 92022
Checksum: 5AE4AC617535DEBC
Sequence:

MGIQGLLQFI QEASEPVNVK KYKGQAVAVD TYCWLHKGAI ACAEKLAKGE PTDRYVGFCM 
KFVNMLLSYG VKPILIFDGC TLPSKKEVER SRRERRQSNL LKGKQLLREG KVSEARDCFA 
RSINITHAMA HKVIKAARAL GVDCLVAPYE ADAQLAYLNK AGIVQAVITE DSDLLAFGCK 
KVILKMDQFG NGLEVDQARL GMCKQLGDVF TEEKFRYMCI LSGCDYLASL RGIGLAKACK 
VLRLANNPDI VKVIKKIGHY LRMNITVPED YITGFIRANN TFLYQLVFDP IQRKLVPLNA 
YGDDVNPETL TYAGQYVGDS VALQIALGNR DVNTFEQIDD YSPDTMPAHS RSHSWNEKAG 
QKPPGTNSIW HKNYCPRLEV NSVSHAPQLK EKPSTLGLKQ VISTKGLNLP RKSCVLKRPR 
NEALAEDDLL SQYSSVSKKI KENGCGDGTS PNSSKMSKSC PDSGTAHKTD AHTPSKMRNK 
FATFLQRRNE ESGAVVVPGT RSRFFCSSQD FDNFIPKKES GQPLNETVAT GKATTSLLGA 
LDCPDTEGHK PVDANGTHNL SSQIPGNAAV SPEDEAQSSE TSKLLGAMSP PSLGTLRSCF 
SWSGTLREFS RTPSPSASTT LQQFRRKSDP PACLPEASAV VTDRCDSKSE MLGETSQPLH 
ELGCSSRSQE SMDSSCGLNT SSLSQPSSRD SGSEESDCNN KSLDNQGEQN SKQHLPHFSK 
KDGLRRNKVP GLCRSSSMDS FSTTKIKPLV PARVSGLSKK SGSMQTRKHH DVENKPGLQT 
KISELWKNFG FKKDSEKLPS CKKPLSPVKD NIQLTPETED EIFNKPECVR AQRAIFH

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: Exo1

Associated with

Other Information

Expression specificity of the mouse exonuclease 1 (mExo1) gene. PubMed ID: 10497278

The transcriptional landscape of the mammalian genome. PubMed ID: 16141072

The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). PubMed ID: 15489334