Details for: Macroh2a1

Gene ID: 26914

Symbol: Macroh2a1

Ensembl ID: ENSMUSG00000015937

Description: macroH2A.1 histone

Associated with

Other Information

Genular Protein ID: 1381771418

Symbol: H2AY_MOUSE

Name: Core histone macro-H2A.1

UniProtKB Accession Codes:

Q9QZQ8 Q91VZ2 Q9QZQ7

Database IDs:

AGR 1 AlphaFoldDB 1 Antibodypedia 1 Bgee 1 BioGRID 1 BioGRID-ORCS 1 CCDS 2 CDD 2 CTD 1 ChEBI 16 ChiTaRS 1 DNASU 1 EMBL 4 Ensembl 2 GO 41 Gene3D 2 GeneTree 1 GlyGen 1 HOGENOM 1 InParanoid 1 IntAct 1 InterPro 8 KEGG 1 MGI 1 MINT 1 NCBI Taxonomy 1 OMA 1 OrthoDB 1 PANTHER 2 PIRSF 1 PRINTS 1 PRO 1 PROSITE 1 PaxDb 1 PeptideAtlas 1 Pfam 3 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 2 Pumba 1 RNAct 1 RefSeq 4 SMART 2 SMR 1 STRING 1 SUPFAM 2 SwissPalm 1 TreeFam 1 UCSC 2 VEuPathDB 1 eggNOG 2 iPTMnet 1 jPOST 1

Citations:

PubMed ID: 10471737

Title: Messenger RNAs encoding mouse histone macroH2A1 isoforms are expressed at similar levels in male and female cells and result from alternative splicing.

PubMed ID: 10471737

DOI: 10.1093/nar/27.18.3685

PubMed ID: 12183056

Title: MacroH2A1.2 binds the nuclear protein Spop.

PubMed ID: 12183056

DOI: 10.1016/s0167-4889(02)00249-5

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 9634239

Title: Histone macroH2A1 is concentrated in the inactive X chromosome of female mammals.

PubMed ID: 9634239

DOI: 10.1038/31275

PubMed ID: 11262398

Title: MACROH2A2, a new member of the MACROH2A core histone family.

PubMed ID: 11262398

DOI: 10.1074/jbc.m010919200

PubMed ID: 15564378

Title: Dynamic relocation of epigenetic chromatin markers reveals an active role of constitutive heterochromatin in the transition from proliferation to quiescence.

PubMed ID: 15564378

DOI: 10.1242/jcs.01537

PubMed ID: 16107708

Title: Structural characterization of the histone variant macroH2A.

PubMed ID: 16107708

DOI: 10.1128/mcb.25.17.7616-7624.2005

PubMed ID: 19144319

Title: The phagosomal proteome in interferon-gamma-activated macrophages.

PubMed ID: 19144319

DOI: 10.1016/j.immuni.2008.11.006

PubMed ID: 21183079

Title: A tissue-specific atlas of mouse protein phosphorylation and expression.

PubMed ID: 21183079

DOI: 10.1016/j.cell.2010.12.001

PubMed ID: 23022728

Title: Splicing switch of an epigenetic regulator by RNA helicases promotes tumor-cell invasiveness.

PubMed ID: 23022728

DOI: 10.1038/nsmb.2390

PubMed ID: 23806337

Title: SIRT5-mediated lysine desuccinylation impacts diverse metabolic pathways.

PubMed ID: 23806337

DOI: 10.1016/j.molcel.2013.06.001

PubMed ID: 28991266

Title: MacroH2A1.1 regulates mitochondrial respiration by limiting nuclear NAD+ consumption.

PubMed ID: 28991266

DOI: 10.1038/nsmb.3481

PubMed ID: 34887560

Title: Evolution of a histone variant involved in compartmental regulation of NAD metabolism.

PubMed ID: 34887560

DOI: 10.1038/s41594-021-00692-5

Sequence Information:

  • Length: 369
  • Mass: 39290
  • Checksum: 33F123DE5C9C46EC
  • Sequence:
    • MSSRGGKKKS TKTSRSAKAG VIFPVGRMLR YIKKGHPKYR IGVGAPVYMA AVLEYLTAEI 
LELAGNAARD NKKGRVTPRH ILLAVANDEE LNQLLKGVTI ASGGVLPNIH PELLAKKRGS 
KGKLEAIITP PPAKKAKSPS QKKPVAKKTG GKKGARKSKK KQGEVSKAAS ADSTTEGTPT 
DGFTVLSTKS LFLGQKLQVV QADIASIDSD AVVHPTNTDF YTGGEVGNTL EKKGGKEFVE 
AVLELRKKNG PLEVAGAAIS AGHGLPAKFV IHCNSPVWGA DKCEELLEKT VKNCLALADD 
RKLKSIAFPS IGSGRNGFPK QTAAQLILKA ISSYFVSTMS SSIKTVYFML FDSESIGIYV 
QEMAKLDAN

Genular Protein ID: 2087855880

Symbol: Q9CTH9_MOUSE

Name: N/A

UniProtKB Accession Codes:

Q9CTH9

Database IDs:

AGR 1 AlphaFoldDB 1 BioGRID-ORCS 1 CTD 1 ChiTaRS 1 DNASU 1 EMBL 2 InterPro 1 KEGG 1 MGI 2 NCBI Taxonomy 1 OrthoDB 1 PeptideAtlas 1 RefSeq 4 SUPFAM 1

Citations:

PubMed ID: 10349636

Title: High-efficiency full-length cDNA cloning.

PubMed ID: 10349636

DOI: 10.1016/S0076-6879(99)03004-9

PubMed ID: 11042159

Title: Normalization and subtraction of cap-trapper-selected cDNAs to prepare full-length cDNA libraries for rapid discovery of new genes.

PubMed ID: 11042159

DOI: 10.1101/gr.145100

PubMed ID: 11076861

Title: RIKEN integrated sequence analysis (RISA) system--384-format sequencing pipeline with 384 multicapillary sequencer.

PubMed ID: 11076861

DOI: 10.1101/gr.152600

PubMed ID: 11217851

Title: Functional annotation of a full-length mouse cDNA collection.

PubMed ID: 11217851

DOI: 10.1038/35055500

PubMed ID: 12466851

Title: Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs.

PubMed ID: 12466851

DOI: 10.1038/nature01266

PubMed ID: 16141073

Title: Antisense Transcription in the Mammalian Transcriptome.

PubMed ID: 16141073

DOI: 10.1126/science.1112009

Sequence Information:

  • Length: 40
  • Mass: 4475
  • Checksum: 583EFBC972EF0575
  • Sequence:
    • AISSYFVSTM SSSIKTVYFM LFDSESIGIY VQEMAKLDAN

Genular Protein ID: 1339632825

Symbol: Q8CA90_MOUSE

Name: N/A

UniProtKB Accession Codes:

Q8CA90

Database IDs:

AGR 1 ARBA 6 AlphaFoldDB 1 BioGRID-ORCS 1 CDD 1 CTD 1 ChiTaRS 1 DNASU 1 EMBL 2 GO 5 Gene3D 1 InterPro 4 MGI 2 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PRINTS 1 PeptideAtlas 1 Pfam 4 RefSeq 1 RuleBase 1 SAM 1 SMART 1 SUPFAM 1 UCSC 1

Citations:

PubMed ID: 10349636

Title: High-efficiency full-length cDNA cloning.

PubMed ID: 10349636

DOI: 10.1016/S0076-6879(99)03004-9

PubMed ID: 11042159

Title: Normalization and subtraction of cap-trapper-selected cDNAs to prepare full-length cDNA libraries for rapid discovery of new genes.

PubMed ID: 11042159

DOI: 10.1101/gr.145100

PubMed ID: 11076861

Title: RIKEN integrated sequence analysis (RISA) system--384-format sequencing pipeline with 384 multicapillary sequencer.

PubMed ID: 11076861

DOI: 10.1101/gr.152600

PubMed ID: 11217851

Title: Functional annotation of a full-length mouse cDNA collection.

PubMed ID: 11217851

DOI: 10.1038/35055500

PubMed ID: 12466851

Title: Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs.

PubMed ID: 12466851

DOI: 10.1038/nature01266

PubMed ID: 16141073

Title: Antisense Transcription in the Mammalian Transcriptome.

PubMed ID: 16141073

DOI: 10.1126/science.1112009

Sequence Information:

  • Length: 198
  • Mass: 20961
  • Checksum: 96BCFFEA7F84DBDA
  • Sequence:
    • MSSRGGKKKS TKTSRSAKAG VIFPVGRMLR YIKKGHPKYR IGVGAPVYMA AVLEYLTAEI 
LELAGNAARD NKKGRVTPRH ILLAVANDEE LNQLLKGVTI ASGGVLPNIH PELLAKKRGS 
KGKLEAIITP PPAKKAKSPS QKKPVAKKTG GKKGARKSKK QGEVSKAASA DSTTEGTPTD 
GFTVLSTKSL FLGQKPPQ

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.