Details for: Mecr

Gene ID: 26922

Symbol: Mecr

Ensembl ID: ENSMUSG00000028910

Description: mitochondrial trans-2-enoyl-CoA reductase

Associated with

Other Information

Genular Protein ID: 4143009778

Symbol: MECR_MOUSE

Name: Enoyl-[acyl-carrier-protein] reductase, mitochondrial

UniProtKB Accession Codes:

Q9DCS3 Q99L39

Database IDs:

AGR 1 AlphaFoldDB 1 Antibodypedia 1 Bgee 1 BioGRID 1 BioGRID-ORCS 1 CCDS 1 CDD 1 CTD 1 ChEBI 46 ChiTaRS 1 DNASU 1 EC 1 EMBL 2 Ensembl 1 ExpressionAtlas 1 GO 11 Gene3D 2 GeneTree 1 HOGENOM 1 InParanoid 1 InterPro 6 KEGG 1 MGI 1 NCBI Taxonomy 1 OMA 1 OrthoDB 1 PANTHER 2 PRO 1 PaxDb 1 PeptideAtlas 1 Pfam 2 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 1 Pumba 1 RNAct 1 Reactome 1 RefSeq 1 Rhea 32 SMART 1 SMR 1 STRING 1 SUPFAM 2 SwissPalm 1 TreeFam 1 UCSC 1 VEuPathDB 1 eggNOG 1 iPTMnet 1 jPOST 1

Citations:

PubMed ID: 16141072

Title: The transcriptional landscape of the mammalian genome.

PubMed ID: 16141072

DOI: 10.1126/science.1112014

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 21183079

Title: A tissue-specific atlas of mouse protein phosphorylation and expression.

PubMed ID: 21183079

DOI: 10.1016/j.cell.2010.12.001

PubMed ID: 23806337

Title: SIRT5-mediated lysine desuccinylation impacts diverse metabolic pathways.

PubMed ID: 23806337

DOI: 10.1016/j.molcel.2013.06.001

PubMed ID: 23576753

Title: Label-free quantitative proteomics of the lysine acetylome in mitochondria identifies substrates of SIRT3 in metabolic pathways.

PubMed ID: 23576753

DOI: 10.1073/pnas.1302961110

PubMed ID: 28369354

Title: Genetic modifications of Mecr reveal a role for mitochondrial 2-enoyl-CoA/ACP reductase in placental development in mice.

PubMed ID: 28369354

DOI: 10.1093/hmg/ddx105

PubMed ID: 30266742

Title: Impaired Mitochondrial Fatty Acid Synthesis Leads to Neurodegeneration in Mice.

PubMed ID: 30266742

DOI: 10.1523/jneurosci.3514-17.2018

Sequence Information:

  • Length: 373
  • Mass: 40343
  • Checksum: EBA9A61A46386AEE
  • Sequence:
    • MLVSQRVTGA RARAPQLAGL LEAWYRHGRT TSSYSALSEP SRVRALVYGN HGDPAKVVQL 
KNLELTAVEG SDVHVRMLAA PINPSDINMI QGNYGLLPKL PAVGGNEGVG QVIAVGSSVS 
ALKPGDWVIP ANAGLGTWRT EAVFSEEALI GIPKDIPLQS AATLGVNPCT AYRMLVDFEQ 
LQPGDSVIQN ASNSGVGQAV IQIASALRLK TINVVRDRPD IKKLTDRLKD LGADYVLTEE 
ELRMPETKTI FKDLPLPRLA LNCVGGKSST ELLRHLAPGG TMVTYGGMAK QPVTASVSLL 
IFKDLKLRGF WLSQWKKNHS PDEFKELILT LCNLIRQGRL TAPSCSEVPL QGYQQALEAS 
MKPFVSSKQI LTM

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.