Details for: Aifm1

Gene ID: 26926

Symbol: Aifm1

Ensembl ID: ENSMUSG00000036932

Description: apoptosis-inducing factor, mitochondrion-associated 1

Associated with

Other Information

Genular Protein ID: 356150035

Symbol: AIFM1_MOUSE

Name: Programmed cell death protein 8

UniProtKB Accession Codes:

Q9Z0X1 Q1L6K5

Database IDs:

AGR 1 AlphaFoldDB 1 Antibodypedia 1 Bgee 1 BioGRID 1 BioGRID-ORCS 1 CCDS 1 CTD 1 ChEBI 29 ChiTaRS 1 DNASU 1 EMBL 3 Ensembl 1 EvolutionaryTrace 1 ExpressionAtlas 1 GO 35 Gene3D 2 GeneTree 1 GlyGen 1 HOGENOM 1 InParanoid 1 IntAct 1 InterPro 5 KEGG 1 MGI 1 MINT 1 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PDB 6 PDBsum 6 PRINTS 2 PRO 1 PaxDb 1 PeptideAtlas 1 Pfam 2 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 1 Pumba 1 RNAct 1 RefSeq 2 Rhea 2 SABIO-RK 1 SMART 1 SMR 1 STRING 1 SUPFAM 2 SwissPalm 1 TreeFam 1 UCSC 1 VEuPathDB 1 eggNOG 1 iPTMnet 1 jPOST 1

Citations:

PubMed ID: 9989411

Title: Molecular characterization of mitochondrial apoptosis-inducing factor.

PubMed ID: 9989411

DOI: 10.1038/17135

PubMed ID: 16644725

Title: Identification and characterization of AIFsh2, a mitochondrial apoptosis-inducing factor (AIF) isoform with NADH oxidase activity.

PubMed ID: 16644725

DOI: 10.1074/jbc.m601751200

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 12114629

Title: Mediation of poly(ADP-ribose) polymerase-1-dependent cell death by apoptosis-inducing factor.

PubMed ID: 12114629

DOI: 10.1126/science.1072221

PubMed ID: 21183079

Title: A tissue-specific atlas of mouse protein phosphorylation and expression.

PubMed ID: 21183079

DOI: 10.1016/j.cell.2010.12.001

PubMed ID: 21467298

Title: Poly(ADP-ribose) (PAR) binding to apoptosis-inducing factor is critical for PAR polymerase-1-dependent cell death (parthanatos).

PubMed ID: 21467298

DOI: 10.1126/scisignal.2000902

PubMed ID: 23806337

Title: SIRT5-mediated lysine desuccinylation impacts diverse metabolic pathways.

PubMed ID: 23806337

DOI: 10.1016/j.molcel.2013.06.001

PubMed ID: 23576753

Title: Label-free quantitative proteomics of the lysine acetylome in mitochondria identifies substrates of SIRT3 in metabolic pathways.

PubMed ID: 23576753

DOI: 10.1073/pnas.1302961110

PubMed ID: 26004228

Title: Interaction between AIF and CHCHD4 Regulates Respiratory Chain Biogenesis.

PubMed ID: 26004228

DOI: 10.1016/j.molcel.2015.04.020

PubMed ID: 30830864

Title: PARP1 inhibition alleviates injury in ARH3-deficient mice and human cells.

PubMed ID: 30830864

DOI: 10.1172/jci.insight.124519

PubMed ID: 11967568

Title: The crystal structure of the mouse apoptosis-inducing factor AIF.

PubMed ID: 11967568

DOI: 10.1038/nsb793

PubMed ID: 19447115

Title: Redox-linked conformational dynamics in apoptosis-inducing factor.

PubMed ID: 19447115

DOI: 10.1016/j.jmb.2009.05.013

Sequence Information:

  • Length: 612
  • Mass: 66765
  • Checksum: A17EDFD5CF77BB85
  • Sequence:
    • MFRCGGLAGA FKQKLVPLVR TVYVQRPKQR NRLPGNLFQQ WRVPLELQMA RQMASSGSSG 
GKMDNSVLVL IVGLSTIGAG AYAYKTIKED QKRYNERVMG LGLSPEEKQR RAIASATEGG 
SVPQIRAPSH VPFLLIGGGT AAFAAARSIR ARDPGARVLI VSEDPELPYM RPPLSKELWF 
SDDPNVTKTL QFRQWNGKER SIYFQPPSFY VSAQDLPNIE NGGVAVLTGK KVVHLDVRGN 
MVKLNDGSQI TFEKCLIATG GTPRSLSAID RAGAEVKSRT TLFRKIGDFR ALEKISREVK 
SITVIGGGFL GSELACALGR KSQASGIEVI QLFPEKGNMG KILPQYLSNW TMEKVKREGV 
KVMPNAIVQS VGVSGGRLLI KLKDGRKVET DHIVTAVGLE PNVELAKTGG LEIDSDFGGF 
RVNAELQARS NIWVAGDAAC FYDIKLGRRR VEHHDHAVVS GRLAGENMTG AAKPYWHQSM 
FWSDLGPDVG YEAIGLVDSS LPTVGVFAKA TAQDNPKSAT EQSGTGIRSE SETESEASEI 
TIPPSAPAVP QVPVEGEDYG KGVIFYLRDK VVVGIVLWNV FNRMPIARKI IKDGEQHEDL 
NEVAKLFNIH ED

Genular Protein ID: 2027351517

Symbol: B1AU25_MOUSE

Name: N/A

UniProtKB Accession Codes:

B1AU25

Database IDs:

AGR 1 ARBA 5 AlphaFoldDB 1 Antibodypedia 1 Bgee 1 BioGRID-ORCS 1 CTD 1 ChEBI 6 ChiTaRS 1 DNASU 1 Ensembl 2 ExpressionAtlas 1 GO 4 Gene3D 2 GeneTree 1 InterPro 6 MGI 2 NCBI Taxonomy 1 OMA 1 OrthoDB 1 PANTHER 2 PRINTS 2 PeptideAtlas 2 Pfam 6 Proteomes 2 ProteomicsDB 2 RefSeq 1 Rhea 1 SAM 2 SMART 1 SMR 1 SUPFAM 2 UCSC 1 VEuPathDB 1 jPOST 1

Citations:

PubMed ID: 19468303

Title: Lineage-specific biology revealed by a finished genome assembly of the mouse.

PubMed ID: 19468303

DOI: 10.1371/journal.pbio.1000112

PubMed ID: 21183079

Title: A tissue-specific atlas of mouse protein phosphorylation and expression.

PubMed ID: 21183079

DOI: 10.1016/j.cell.2010.12.001

PubMed ID: 21750661

Title: Modernizing reference genome assemblies.

PubMed ID: 21750661

PubMed ID: 23806337

Title: SIRT5-mediated lysine desuccinylation impacts diverse metabolic pathways.

PubMed ID: 23806337

DOI: 10.1016/j.molcel.2013.06.001

PubMed ID: 23576753

Title: Label-free quantitative proteomics of the lysine acetylome in mitochondria identifies substrates of SIRT3 in metabolic pathways.

PubMed ID: 23576753

DOI: 10.1073/pnas.1302961110

Sequence Information:

  • Length: 608
  • Mass: 66114
  • Checksum: 920D716B597A0E6F
  • Sequence:
    • MFRCGGLAGA FKQKLVPLVR TVYVQRPKQR NRLPVVQCHL LGSPSRTLAS AGASGKDGSS 
LVYFLIVGAT VTGAGIYYAY KTIKEDQKRY NERVMGLGLS PEEKQRRAIA SATEGGSVPQ 
IRAPSHVPFL LIGGGTAAFA AARSIRARDP GARVLIVSED PELPYMRPPL SKELWFSDDP 
NVTKTLQFRQ WNGKERSIYF QPPSFYVSAQ DLPNIENGGV AVLTGKKVVH LDVRGNMVKL 
NDGSQITFEK CLIATGGTPR SLSAIDRAGA EVKSRTTLFR KIGDFRALEK ISREVKSITV 
IGGGFLGSEL ACALGRKSQA SGIEVIQLFP EKGNMGKILP QYLSNWTMEK VKREGVKVMP 
NAIVQSVGVS GGRLLIKLKD GRKVETDHIV TAVGLEPNVE LAKTGGLEID SDFGGFRVNA 
ELQARSNIWV AGDAACFYDI KLGRRRVEHH DHAVVSGRLA GENMTGAAKP YWHQSMFWSD 
LGPDVGYEAI GLVDSSLPTV GVFAKATAQD NPKSATEQSG TGIRSESETE SEASEITIPP 
SAPAVPQVPV EGEDYGKGVI FYLRDKVVVG IVLWNVFNRM PIARKIIKDG EQHEDLNEVA 
KLFNIHED

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.