Details for: Cadps

Gene ID: 26989

Symbol: Cadps

Ensembl ID: ENSRNOG00000008570

Description: calcium dependent secretion activator

Associated with

Other Information

Genular Protein ID: 1743004796

Symbol: CAPS1_RAT

Name: Calcium-dependent secretion activator 1

UniProtKB Accession Codes:

Database IDs:

Citations:

PubMed ID: 9289490

Title: Novel Ca2+-binding protein (CAPS) related to UNC-31 required for Ca2+-activated exocytosis.

PubMed ID: 9289490

DOI: 10.1074/jbc.272.32.19637

PubMed ID: 1516133

Title: A novel 145 kd brain cytosolic protein reconstitutes Ca(2+)-regulated secretion in permeable neuroendocrine cells.

PubMed ID: 1516133

DOI: 10.1016/0092-8674(92)90310-9

PubMed ID: 9162085

Title: Docked secretory vesicles undergo Ca2+-activated exocytosis in a cell-free system.

PubMed ID: 9162085

DOI: 10.1074/jbc.272.22.14447

PubMed ID: 9525942

Title: Specific binding of phosphatidylinositol 4,5-bisphosphate to calcium-dependent activator protein for secretion (CAPS), a potential phosphoinositide effector protein for regulated exocytosis.

PubMed ID: 9525942

DOI: 10.1074/jbc.273.14.8337

PubMed ID: 9697858

Title: CAPS (mammalian UNC-31) protein localizes to membranes involved in dense-core vesicle exocytosis.

PubMed ID: 9697858

DOI: 10.1016/s0896-6273(00)80521-8

PubMed ID: 9697859

Title: Differential regulation of exocytosis by calcium and CAPS in semi-intact synaptosomes.

PubMed ID: 9697859

DOI: 10.1016/s0896-6273(00)80522-x

PubMed ID: 10792045

Title: Rapid regulated dense-core vesicle exocytosis requires the CAPS protein.

PubMed ID: 10792045

DOI: 10.1073/pnas.090359097

PubMed ID: 11927595

Title: Membrane association domains in Ca2+-dependent activator protein for secretion mediate plasma membrane and dense-core vesicle binding required for Ca2+-dependent exocytosis.

PubMed ID: 11927595

DOI: 10.1074/jbc.m201614200

PubMed ID: 14530279

Title: A family of Ca2+-dependent activator proteins for secretion: comparative analysis of structure, expression, localization, and function.

PubMed ID: 14530279

DOI: 10.1074/jbc.m304727200

PubMed ID: 15312653

Title: CAPS acts at a prefusion step in dense-core vesicle exocytosis as a PIP2 binding protein.

PubMed ID: 15312653

DOI: 10.1016/j.neuron.2004.07.028

PubMed ID: 22673903

Title: Quantitative maps of protein phosphorylation sites across 14 different rat organs and tissues.

PubMed ID: 22673903

DOI: 10.1038/ncomms1871

Sequence Information:

  • Length: 1289
  • Mass: 146266
  • Checksum: 2ADAEA35FB20BCDD
  • Sequence:
  • MLDPSSSEEE SDEILEEESG KEVLGSAASG ARLSPSRTNE GSAGSAGMGG SGAGAGVGAG 
    GGGGSGASSG GGAGGLQPSS RAGGGRPSSP SPSVVSEKEK EELERLQKEE EERKKRLQLY 
    VFVMRCIAYP FNAKQPTDMA RRPRKISKQQ LQTVKDRFQA FLNGETQIVA DEAFMNAVQS 
    YYEVFLKSDR VARMVQSGGC SANDSREVFK KHIEKRVRSL PEIDGLSKET VLSSWMAKFD 
    AIYRGEEDPR KQQARMTASA ASELILSKEQ LYEMFQNILG IKKFEHQLLY NACQLDNPDE 
    QAAQIRRELD GRLQMADQIA RERKFPKFVS KEMENMYIEE LKSSVNLLMA NLESMPVSKG 
    GEFKLQKLKR SHNASIIDMG EESENQLSKS DVLLSFSLEV VIMEVQGLKS LAPNRIVYCT 
    MEVEGGEKLQ TDQAEASKPT WGTQGDFSTT HALPAVKVKL FTESTGVLAL EDKELGRVIL 
    HPTPNSPKQS EWHKMTVSKN CPDQDLKIKL AVRMDKPQNM KHSGYLWTIG KNVWKRWKKR 
    FFVLVQVSQY TFAMCSYREK KAEPQELLQL DGYTVDYTDP QPGLEGGRAF FNAVKEGDTV 
    IFASDDEQDR ILWVQAMYRA TGQSHKPVPP TQVQKLKPRA ETCLSMDAPI SQFYADRAQK 
    HGMDEFISSN PCNFDHASLF EMVQRLTLDH RLNDSYSCLG WFSPGQVFVL DEYCARNGVR 
    GCHRHLCYLR DLLERAENGA MIDPTLLHYS FAFCASHVHG NRPDGIGTVT VEEKERFEEI 
    KERLRVLLEN QITHFRYCFP FGRPEGALKA TLSLLERVLM KDIVTPVPQE EVKTVIRKCL 
    EQAALVNYSR LSEYAKIEEN VGRLITPAKK LEDTIRLAEL VIEVLQQNEE HHAEAFAWWS 
    DLMVEHAETF LSLFAVDMDA ALEVQPPDTW DSFPLFQLLN DFLRTDYNLC NGKFHKHLQD 
    LFAPLVVRYV DLMESSIAQS IHRGFERESW EPVNNGSGTS EDLFWKLDAL QTFIRDLHWP 
    EEEFGKHLEQ RLKLMASDMI ESCVKRTRIA FEVKLQKTSR STDFRVPQSI CTMFNVMVDA 
    KAQSTKLCSM EMGQEHQYHS KIDELIEETV KEMITLLVAK FVTILEGVLA KLSRYDEGTL 
    FSSFLSFTVK AASKYVDVPK PGMDVADAYV TFVRHSQDVL RDKVNEEMYI ERLFDQWYNS 
    SMNVICTWLT DRMDLQLHIY QLKTLIRMVK KTYRDFRLQG VLDSTLNSKT YETIRNRLTV 
    EERTASVSEG GGLQGISMKD SDEEDEEDD

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.