Brd7 | ENSMUSG00000031660 | NCBI 26992

Details for: Brd7

Gene ID: 26992

Symbol: Brd7

Ensembl ID: ENSMUSG00000031660

Description: bromodomain containing 7

Associated with

Gene expression (transcription)
(R-MMU-74160)
Generic transcription pathway
(R-MMU-212436)
Regulation of tp53 activity
(R-MMU-5633007)
Regulation of tp53 activity through acetylation
(R-MMU-6804758)
Rna polymerase ii transcription
(R-MMU-73857)
Transcriptional regulation by tp53
(R-MMU-3700989)
Chromatin
(GO:0000785)
Chromatin remodeling
(GO:0006338)
Cytosol
(GO:0005829)
Histone binding
(GO:0042393)
Kinetochore
(GO:0000776)
Lysine-acetylated histone binding
(GO:0070577)
Negative regulation of dna-templated transcription
(GO:0045892)
Negative regulation of g1/s transition of mitotic cell cycle
(GO:2000134)
Nuclear matrix
(GO:0016363)
Nucleoplasm
(GO:0005654)
Nucleus
(GO:0005634)
P53 binding
(GO:0002039)
Positive regulation of cell differentiation
(GO:0045597)
Positive regulation of dna-templated transcription
(GO:0045893)
Positive regulation of double-strand break repair
(GO:2000781)
Positive regulation of myoblast differentiation
(GO:0045663)
Positive regulation of t cell differentiation
(GO:0045582)
Protein binding
(GO:0005515)
Regulation of g0 to g1 transition
(GO:0070316)
Regulation of g1/s transition of mitotic cell cycle
(GO:2000045)
Regulation of mitotic cell cycle
(GO:0007346)
Regulation of mitotic metaphase/anaphase transition
(GO:0030071)
Regulation of nucleotide-excision repair
(GO:2000819)
Regulation of transcription by rna polymerase ii
(GO:0006357)
Rsc-type complex
(GO:0016586)
Swi/snf superfamily-type complex
(GO:0070603)
Transcription cis-regulatory region binding
(GO:0000976)
Transcription coactivator activity
(GO:0003713)
Transcription corepressor activity
(GO:0003714)
Transcription factor binding
(GO:0008134)
Transcription initiation-coupled chromatin remodeling
(GO:0045815)
Wnt signaling pathway
(GO:0016055)

Other Information

Proteins

Bromodomain-containing protein 7

Genular Protein ID: 1741559401

Symbol: BRD7_MOUSE

Name: Bromodomain-containing protein 7

UniProtKB Accession Codes:

O88665 Q3UQ56 Q3UU06 Q9CT78

Database IDs:

Citations:

PubMed ID: 10526152

Title: Identification and molecular characterization of BP75, a novel bromodomain-containing protein.

PubMed ID: 10526152

DOI: 10.1016/s0014-5793(99)01191-6

PubMed ID: 16141072

Title: The transcriptional landscape of the mammalian genome.

PubMed ID: 16141072

DOI: 10.1126/science.1112014

PubMed ID: 12941796

Title: BP75, bromodomain-containing M(r) 75,000 protein, binds dishevelled-1 and enhances Wnt signaling by inactivating glycogen synthase kinase-3 beta.

PubMed ID: 12941796

PubMed ID: 18809673

Title: BRD7, a novel PBAF-specific SWI/SNF subunit, is required for target gene activation and repression in embryonic stem cells.

PubMed ID: 18809673

DOI: 10.1074/jbc.m806061200

PubMed ID: 19909775

Title: TRIM24 mediates ligand-dependent activation of androgen receptor and is repressed by a bromodomain-containing protein, BRD7, in prostate cancer cells.

PubMed ID: 19909775

DOI: 10.1016/j.bbamcr.2009.11.001

PubMed ID: 21183079

Title: A tissue-specific atlas of mouse protein phosphorylation and expression.

PubMed ID: 21183079

DOI: 10.1016/j.cell.2010.12.001

PubMed ID: 23806337

Title: SIRT5-mediated lysine desuccinylation impacts diverse metabolic pathways.

PubMed ID: 23806337

DOI: 10.1016/j.molcel.2013.06.001

Sequence Information:

Length: 651
Mass: 74000
Checksum: 5D34B4F14FD51350
Sequence:

MGKKHKKHKS DRHFYEEYVE KPLKLVLKVG GSEVTELSTG SSGHDSSLFE DRSDHDKHKD 
RKRKKRKKGE KQAPGEEKGR KRRRVKEDKK KRDRDRAENE VDRDLQCHVP IRLDLPPEKP 
LTSSLAKQEE VEQTPLQEAL NQLMRQLQRK DPSAFFSFPV TDFIAPGYSM IIKHPMDFST 
MKEKIKNNDY QSIEELKDNF KLMCTNAMIY NKPETIYYKA AKKLLHSGMK ILSQERIQSL 
KQSIDFMSDL QKTRKQKERT DACQSGEDSG CWQREREDSG DAETQAFRSP AKDNKRKDKD 
VLEDKWRSSN SEREHEQIER VVQESGGKLT RRLANSQCEF ERRKPDGTTT LGLLHPVDPI 
VGEPGYCPVR LGMTTGRLQS GVNTLQGFKE DKRNRVTPVL YLNYGPYSSY APHYDSTFAN 
ISKDDSDLIY STYGEDSDLP NNFSISEFLA TCQDYPYVMA DSLLDVLTKG GHSRSLQDLD 
MSSPEDEGQT RALDTAKEAE ITQIEPTGRL ESSSQDRLTA LQAVTTFGAP AEVFDSEEAE 
VFQRKLDETT RLLRELQEAQ NERLSTRPPP NMICLLGPSY REMYLAEQVT NNLKELTQQV 
TPGDVVSIHG VRKAMGISVP SPIVGNSFVD LTGECEEPKE TSTAECGPDA S

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: Brd7

Associated with

Other Information

Identification and molecular characterization of BP75, a novel bromodomain-containing protein. PubMed ID: 10526152

The transcriptional landscape of the mammalian genome. PubMed ID: 16141072

BP75, bromodomain-containing M(r) 75,000 protein, binds dishevelled-1 and enhances Wnt signaling by inactivating glycogen synthase kinase-3 beta. PubMed ID: 12941796

BRD7, a novel PBAF-specific SWI/SNF subunit, is required for target gene activation and repression in embryonic stem cells. PubMed ID: 18809673

TRIM24 mediates ligand-dependent activation of androgen receptor and is repressed by a bromodomain-containing protein, BRD7, in prostate cancer cells. PubMed ID: 19909775

A tissue-specific atlas of mouse protein phosphorylation and expression. PubMed ID: 21183079

SIRT5-mediated lysine desuccinylation impacts diverse metabolic pathways. PubMed ID: 23806337