Rps3 | ENSMUSG00000030744 | NCBI 27050

Details for: Rps3

Gene ID: 27050

Symbol: Rps3

Ensembl ID: ENSMUSG00000030744

Description: ribosomal protein S3

Associated with

Activation of the mrna upon binding of the cap-binding complex and eifs, and subsequent binding to 43s
(R-MMU-72662)
Cap-dependent translation initiation
(R-MMU-72737)
Eukaryotic translation initiation
(R-MMU-72613)
Formation of a pool of free 40s subunits
(R-MMU-72689)
Formation of the ternary complex, and subsequently, the 43s complex
(R-MMU-72695)
Gtp hydrolysis and joining of the 60s ribosomal subunit
(R-MMU-72706)
L13a-mediated translational silencing of ceruloplasmin expression
(R-MMU-156827)
Major pathway of rrna processing in the nucleolus and cytosol
(R-MMU-6791226)
Metabolism of proteins
(R-MMU-392499)
Metabolism of rna
(R-MMU-8953854)
Nonsense-mediated decay (nmd)
(R-MMU-927802)
Nonsense mediated decay (nmd) enhanced by the exon junction complex (ejc)
(R-MMU-975957)
Nonsense mediated decay (nmd) independent of the exon junction complex (ejc)
(R-MMU-975956)
Ribosomal scanning and start codon recognition
(R-MMU-72702)
Rrna processing
(R-MMU-72312)
Rrna processing in the nucleus and cytosol
(R-MMU-8868773)
Srp-dependent cotranslational protein targeting to membrane
(R-MMU-1799339)
Translation
(R-MMU-72766)
Translation initiation complex formation
(R-MMU-72649)
Apoptotic process
(GO:0006915)
Base-excision repair
(GO:0006284)
Cell division
(GO:0051301)
Cellular response to hydrogen peroxide
(GO:0070301)
Cellular response to nerve growth factor stimulus
(GO:1990090)
Cellular response to reactive oxygen species
(GO:0034614)
Cellular response to tumor necrosis factor
(GO:0071356)
Chromosome segregation
(GO:0007059)
Class i dna-(apurinic or apyrimidinic site) endonuclease activity
(GO:0140078)
Cytoplasm
(GO:0005737)
Cytoplasmic translation
(GO:0002181)
Cytosol
(GO:0005829)
Cytosolic ribosome
(GO:0022626)
Cytosolic small ribosomal subunit
(GO:0022627)
Damaged dna binding
(GO:0003684)
Dendrite
(GO:0030425)
Dna-(apurinic or apyrimidinic site) endonuclease activity
(GO:0003906)
Dna-binding transcription factor binding
(GO:0140297)
Dna binding
(GO:0003677)
Dna damage response
(GO:0006974)
Dna endonuclease activity
(GO:0004520)
Dna repair
(GO:0006281)
Endoplasmic reticulum
(GO:0005783)
Enzyme binding
(GO:0019899)
Hsp70 protein binding
(GO:0030544)
Hsp90 protein binding
(GO:0051879)
Kinase binding
(GO:0019900)
Microtubule binding
(GO:0008017)
Mitochondrial inner membrane
(GO:0005743)
Mitochondrial matrix
(GO:0005759)
Mrna binding
(GO:0003729)
Negative regulation of dna repair
(GO:0045738)
Negative regulation of protein ubiquitination
(GO:0031397)
Negative regulation of translation
(GO:0017148)
Nucleolus
(GO:0005730)
Nucleus
(GO:0005634)
Oxidized purine dna binding
(GO:0032357)
Oxidized pyrimidine dna binding
(GO:0032358)
Plasma membrane
(GO:0005886)
Positive regulation of activated t cell proliferation
(GO:0042104)
Positive regulation of apoptotic signaling pathway
(GO:2001235)
Positive regulation of base-excision repair
(GO:1905053)
Positive regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis
(GO:2001272)
Positive regulation of dna repair
(GO:0045739)
Positive regulation of endodeoxyribonuclease activity
(GO:0032079)
Positive regulation of gene expression
(GO:0010628)
Positive regulation of interleukin-2 production
(GO:0032743)
Positive regulation of intrinsic apoptotic signaling pathway in response to dna damage
(GO:1902231)
Positive regulation of jun kinase activity
(GO:0043507)
Positive regulation of microtubule polymerization
(GO:0031116)
Positive regulation of nf-kappab transcription factor activity
(GO:0051092)
Positive regulation of non-canonical nf-kappab signal transduction
(GO:1901224)
Positive regulation of protein-containing complex assembly
(GO:0031334)
Positive regulation of t cell receptor signaling pathway
(GO:0050862)
Postsynaptic density
(GO:0014069)
Protein-containing complex binding
(GO:0044877)
Protein binding
(GO:0005515)
Protein kinase a binding
(GO:0051018)
Protein kinase binding
(GO:0019901)
Regulation of apoptotic process
(GO:0042981)
Response to tnf agonist
(GO:0061481)
Ribosome
(GO:0005840)
Rna binding
(GO:0003723)
Rna polymerase ii transcription regulatory region sequence-specific dna binding
(GO:0000977)
Ruffle membrane
(GO:0032587)
Small ribosomal subunit rrna binding
(GO:0070181)
Spindle assembly
(GO:0051225)
Structural constituent of ribosome
(GO:0003735)
Supercoiled dna binding
(GO:0097100)
Synapse
(GO:0045202)
Tubulin binding
(GO:0015631)
Ubiquitin-like protein conjugating enzyme binding
(GO:0044390)

Other Information

Proteins

40S ribosomal protein S3

Genular Protein ID: 1058141322

Symbol: RS3_MOUSE

Name: 40S ribosomal protein S3

UniProtKB Accession Codes:

P62908 P17073 P47933

Database IDs:

Citations:

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 7775413

Title: Implication of mammalian ribosomal protein S3 in the processing of DNA damage.

PubMed ID: 7775413

DOI: 10.1074/jbc.270.23.13620

PubMed ID: 14988002

Title: RpS3, a DNA repair endonuclease and ribosomal protein, is involved in apoptosis.

PubMed ID: 14988002

DOI: 10.1016/s0014-5793(04)00074-2

PubMed ID: 17242355

Title: Large-scale phosphorylation analysis of mouse liver.

PubMed ID: 17242355

DOI: 10.1073/pnas.0609836104

PubMed ID: 19144319

Title: The phagosomal proteome in interferon-gamma-activated macrophages.

PubMed ID: 19144319

DOI: 10.1016/j.immuni.2008.11.006

PubMed ID: 19129230

Title: Molecular characterization of Mybbp1a as a co-repressor on the Period2 promoter.

PubMed ID: 19129230

DOI: 10.1093/nar/gkn1013

PubMed ID: 21183079

Title: A tissue-specific atlas of mouse protein phosphorylation and expression.

PubMed ID: 21183079

DOI: 10.1016/j.cell.2010.12.001

PubMed ID: 23806337

Title: SIRT5-mediated lysine desuccinylation impacts diverse metabolic pathways.

PubMed ID: 23806337

DOI: 10.1016/j.molcel.2013.06.001

PubMed ID: 28575669

Title: The mammalian ribo-interactome reveals ribosome functional diversity and heterogeneity.

PubMed ID: 28575669

DOI: 10.1016/j.cell.2017.05.022

PubMed ID: 36517592

Title: A male germ-cell-specific ribosome controls male fertility.

PubMed ID: 36517592

DOI: 10.1038/s41586-022-05508-0

Sequence Information:

Length: 243
Mass: 26674
Checksum: 6B9BB34FDEE04AAF
Sequence:

MAVQISKKRK FVADGIFKAE LNEFLTRELA EDGYSGVEVR VTPTRTEIII LATRTQNVLG 
EKGRRIRELT AVVQKRFGFP EGSVELYAEK VATRGLCAIA QAESLRYKLL GGLAVRRACY 
GVLRFIMESG AKGCEVVVSG KLRGQRAKSM KFVDGLMIHS GDPVNYYVDT AVRHVLLRQG 
VLGIKVKIML PWDPSGKIGP KKPLPDHVSI VEPKDEILPT TPISEQKGGK PEPPAMPQPV 
PTA

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: Rps3

Associated with

Other Information

The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). PubMed ID: 15489334

Implication of mammalian ribosomal protein S3 in the processing of DNA damage. PubMed ID: 7775413

RpS3, a DNA repair endonuclease and ribosomal protein, is involved in apoptosis. PubMed ID: 14988002

Large-scale phosphorylation analysis of mouse liver. PubMed ID: 17242355

The phagosomal proteome in interferon-gamma-activated macrophages. PubMed ID: 19144319

Molecular characterization of Mybbp1a as a co-repressor on the Period2 promoter. PubMed ID: 19129230

A tissue-specific atlas of mouse protein phosphorylation and expression. PubMed ID: 21183079

SIRT5-mediated lysine desuccinylation impacts diverse metabolic pathways. PubMed ID: 23806337

The mammalian ribo-interactome reveals ribosome functional diversity and heterogeneity. PubMed ID: 28575669

A male germ-cell-specific ribosome controls male fertility. PubMed ID: 36517592