Details for: Slamf1

Gene ID: 27218

Symbol: Slamf1

Ensembl ID: ENSMUSG00000015316

Description: signaling lymphocytic activation molecule family member 1

Associated with

Other Information

Genular Protein ID: 2744223859

Symbol: SLAF1_MOUSE

Name: Signaling lymphocytic activation molecule

UniProtKB Accession Codes:

Database IDs:

Citations:

PubMed ID: 10570270

Title: Molecular and functional characterization of mouse signaling lymphocytic activation molecule (SLAM): differential expression and responsiveness in Th1 and Th2 cells.

PubMed ID: 10570270

PubMed ID: 15123745

Title: The cell surface receptor SLAM controls T cell and macrophage functions.

PubMed ID: 15123745

DOI: 10.1084/jem.20031835

PubMed ID: 9126961

Title: Engagement of the signaling lymphocytic activation molecule (SLAM) on activated T cells results in IL-2-independent, cyclosporin A-sensitive T cell proliferation and IFN-gamma production.

PubMed ID: 9126961

PubMed ID: 9774102

Title: The X-linked lymphoproliferative-disease gene product SAP regulates signals induced through the co-receptor SLAM.

PubMed ID: 9774102

DOI: 10.1038/26683

PubMed ID: 11689425

Title: Structural basis for the interaction of the free SH2 domain EAT-2 with SLAM receptors in hematopoietic cells.

PubMed ID: 11689425

DOI: 10.1093/emboj/20.21.5840

PubMed ID: 11477403

Title: Regulation of SLAM-mediated signal transduction by SAP, the X-linked lymphoproliferative gene product.

PubMed ID: 11477403

DOI: 10.1038/90615

PubMed ID: 12351401

Title: The role of SAP in murine CD150 (SLAM)-mediated T-cell proliferation and interferon gamma production.

PubMed ID: 12351401

DOI: 10.1182/blood-2002-02-0445

PubMed ID: 15315965

Title: The adaptor protein SH2D1A regulates signaling through CD150 (SLAM) in B cells.

PubMed ID: 15315965

DOI: 10.1182/blood-2004-04-1273

PubMed ID: 15539155

Title: SAP regulates T(H)2 differentiation and PKC-theta-mediated activation of NF-kappaB1.

PubMed ID: 15539155

DOI: 10.1016/j.immuni.2004.09.012

PubMed ID: 16528012

Title: The costimulatory molecule SLAM is critical for pulmonary allergic responses.

PubMed ID: 16528012

DOI: 10.1165/rcmb.2005-0294oc

PubMed ID: 16847311

Title: Association between SAP and FynT: Inducible SH3 domain-mediated interaction controlled by engagement of the SLAM receptor.

PubMed ID: 16847311

DOI: 10.1128/mcb.00357-06

PubMed ID: 18031695

Title: Homotypic interactions mediated by Slamf1 and Slamf6 receptors control NKT cell lineage development.

PubMed ID: 18031695

DOI: 10.1016/j.immuni.2007.08.020

PubMed ID: 18606638

Title: Impaired SLAM-SLAM homotypic interaction between invariant NKT cells and dendritic cells affects differentiation of IL-4/IL-10-secreting NKT2 cells in nonobese diabetic mice.

PubMed ID: 18606638

DOI: 10.4049/jimmunol.181.2.869

PubMed ID: 21183079

Title: A tissue-specific atlas of mouse protein phosphorylation and expression.

PubMed ID: 21183079

DOI: 10.1016/j.cell.2010.12.001

PubMed ID: 20525889

Title: Germinal center T follicular helper cell IL-4 production is dependent on signaling lymphocytic activation molecule receptor (CD150).

PubMed ID: 20525889

DOI: 10.4049/jimmunol.0903505

PubMed ID: 20818396

Title: SLAM is a microbial sensor that regulates bacterial phagosome functions in macrophages.

PubMed ID: 20818396

DOI: 10.1038/ni.1931

PubMed ID: 22493499

Title: Receptor signaling lymphocyte-activation molecule family 1 (Slamf1) regulates membrane fusion and NADPH oxidase 2 (NOX2) activity by recruiting a Beclin-1/Vps34/ultraviolet radiation resistance-associated gene (UVRAG) complex.

PubMed ID: 22493499

DOI: 10.1074/jbc.m112.367060

PubMed ID: 25926831

Title: Negative regulation of humoral immunity due to interplay between the SLAMF1, SLAMF5, and SLAMF6 receptors.

PubMed ID: 25926831

DOI: 10.3389/fimmu.2015.00158

Sequence Information:

  • Length: 343
  • Mass: 38094
  • Checksum: 7980470157E834C4
  • Sequence:
  • MDPKGSLSWR ILLFLSLAFE LSYGTGGGVM DCPVILQKLG QDTWLPLTNE HQINKSVNKS 
    VRILVTMATS PGSKSNKKIV SFDLSKGSYP DHLEDGYHFQ SKNLSLKILG NRRESEGWYL 
    VSVEENVSVQ QFCKQLKLYE QVSPPEIKVL NKTQENENGT CSLLLACTVK KGDHVTYSWS 
    DEAGTHLLSR ANRSHLLHIT LSNQHQDSIY NCTASNPVSS ISRTFNLSSQ ACKQESSSES 
    SPWMQYTLVP LGVVIIFILV FTAIIMMKRQ GKSNHCQPPV EEKSLTIYAQ VQKSGPQEKK 
    LHDALTDQDP CTTIYVAATE PAPESVQEPN PTTVYASVTL PES

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.