Details for: Trp53bp1

Gene ID: 27223

Symbol: Trp53bp1

Ensembl ID: ENSMUSG00000043909

Description: transformation related protein 53 binding protein 1

Associated with

Other Information

Genular Protein ID: 432307091

Symbol: TP53B_MOUSE

Name: N/A

UniProtKB Accession Codes:

Database IDs:

Citations:

PubMed ID: 19468303

Title: Lineage-specific biology revealed by a finished genome assembly of the mouse.

PubMed ID: 19468303

DOI: 10.1371/journal.pbio.1000112

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 11801725

Title: Kinetochore localisation of the DNA damage response component 53BP1 during mitosis.

PubMed ID: 11801725

DOI: 10.1242/jcs.115.1.71

PubMed ID: 8910340

Title: p202, an interferon-inducible modulator of transcription, inhibits transcriptional activation by the p53 tumor suppressor protein, and a segment from the p53-binding protein 1 that binds to p202 overcomes this inhibition.

PubMed ID: 8910340

DOI: 10.1074/jbc.271.44.27544

PubMed ID: 11673449

Title: Histone H2AX is phosphorylated in an ATR-dependent manner in response to replicational stress.

PubMed ID: 11673449

DOI: 10.1074/jbc.c100569200

PubMed ID: 12640136

Title: p53 Binding protein 53BP1 is required for DNA damage responses and tumor suppression in mice.

PubMed ID: 12640136

DOI: 10.1128/mcb.23.7.2556-2563.2003

PubMed ID: 15159415

Title: 53BP1 is required for class switch recombination.

PubMed ID: 15159415

DOI: 10.1083/jcb.200403021

PubMed ID: 15077110

Title: 53BP1 links DNA damage-response pathways to immunoglobulin heavy chain class-switch recombination.

PubMed ID: 15077110

DOI: 10.1038/ni1067

PubMed ID: 19144319

Title: The phagosomal proteome in interferon-gamma-activated macrophages.

PubMed ID: 19144319

DOI: 10.1016/j.immuni.2008.11.006

PubMed ID: 19131326

Title: Large scale localization of protein phosphorylation by use of electron capture dissociation mass spectrometry.

PubMed ID: 19131326

DOI: 10.1074/mcp.m800451-mcp200

PubMed ID: 20362325

Title: 53BP1 inhibits homologous recombination in Brca1-deficient cells by blocking resection of DNA breaks.

PubMed ID: 20362325

DOI: 10.1016/j.cell.2010.03.012

PubMed ID: 21183079

Title: A tissue-specific atlas of mouse protein phosphorylation and expression.

PubMed ID: 21183079

DOI: 10.1016/j.cell.2010.12.001

PubMed ID: 20453858

Title: 53BP1 loss rescues BRCA1 deficiency and is associated with triple-negative and BRCA-mutated breast cancers.

PubMed ID: 20453858

DOI: 10.1038/nsmb.1831

PubMed ID: 23209566

Title: Impact of histone H4 lysine 20 methylation on 53BP1 responses to chromosomal double strand breaks.

PubMed ID: 23209566

DOI: 10.1371/journal.pone.0049211

PubMed ID: 23333305

Title: RIF1 is essential for 53BP1-dependent nonhomologous end joining and suppression of DNA double-strand break resection.

PubMed ID: 23333305

DOI: 10.1016/j.molcel.2013.01.002

PubMed ID: 23306439

Title: Rif1 prevents resection of DNA breaks and promotes immunoglobulin class switching.

PubMed ID: 23306439

DOI: 10.1126/science.1230624

PubMed ID: 24129315

Title: Immunoaffinity enrichment and mass spectrometry analysis of protein methylation.

PubMed ID: 24129315

DOI: 10.1074/mcp.o113.027870

PubMed ID: 26308889

Title: Orientation-specific joining of AID-initiated DNA breaks promotes antibody class switching.

PubMed ID: 26308889

DOI: 10.1038/nature14970

PubMed ID: 30297459

Title: Phosphorylation of TIP60 Suppresses 53BP1 Localization at DNA Damage Sites.

PubMed ID: 30297459

DOI: 10.1128/mcb.00209-18

PubMed ID: 15341721

Title: The Tudor tandem of 53BP1: a new structural motif involved in DNA and RG-rich peptide binding.

PubMed ID: 15341721

DOI: 10.1016/j.str.2004.06.014

Sequence Information:

  • Length: 1969
  • Mass: 212735
  • Checksum: F673EA87B3BA1FDE
  • Sequence:
  • MPGEQMDPTG SQLDSDFSQQ DTPCLIIEDS QPESQVLEED AGSHFSVLSR HLPNLQMHKE 
    NPVLDIVSNP EQSAVEQGDS NSSFNEHLKE KKASDPVESS HLGTSGSISQ VIERLPQPNR 
    TSSALAVTVE AASLPEEEKE EEELEEEKEG VGANAPGADS LAAEDSASSQ LGFGVLELSQ 
    SQDVEEHTVP YDVNQEHLQL VTTNSGSSPL SDVDASTAIK CEEQPTEDIA MIEQPSKDIP 
    VTVQPGKGIH VVEEQNLPLV RSEDRPSSPQ VSVAAVETKE QVPARELLEE GPQVQPSSEP 
    EVSSTQEDLF DQSSKTASDG CSTPSREEGG CSPVSTPATT LQLLQLSGQK PLVQESLSTN 
    SSDLVAPSPD AFRSTPFIVP SSPTEQGGRK DEPMDMSVIP VGGEPFQKLH DDEAMETEKP 
    LLPSQPAVSP QASTPVSRST PVFTPGSLPI PSQPEFSHDI FIPSPSLEEP SDDVKKGGGL 
    HSSSLTVECS KTSESEPKNF TDDLGLSMTG DSCKLMLSTS EYSQSSKMES LGSPRTEEDR 
    ENTQIDDTEP LSPVSNSKLP ADSENVLVTP SQDDQVEMSQ NVDKAKEDET EDRGDCKGRE 
    DAVAEDVCID LTCDSGSQAV PSPATRSEAL SSVLDQEEAM DTKEHHPEEG FSGSEVEEVP 
    ETPCGSHREE PKEEPMESIP LHLSLTETQS EALCLQKEAP KEECPEAMEV ETSVISIDSP 
    QKLQVLDQEL EHKDPDTWEE ATSEDSSVVI VDVKEPSPRA DVSCEPLEEV EKCSDSQSWE 
    GVAPEEEPCA ENRLDTPEEK RIECDGDSKA ETTEKDAVTE DSPQPPLPSV RDEPVRPDQE 
    TQQPQVQEKE SPVTVDAEVA DDKQLGPEGA CQQLEKAPAC ASQSFCESSS ETPFHFTLPK 
    EGDIIPPLTG ATPPLIGHLK LEPKRHSTPI GISNYPESTI ATSDVTSESM VEINDPLLGN 
    EKGDSESAPE MDGKLSLKMK LVSPETEASE ESLQFSLEKP TTAERKNGST AIAEPVASLQ 
    KPVPVFGCIY EAQQEKEAQS EAPPSAPDRA NLLHFPSAQE EDKERPDVTP KLRQSEQPVK 
    PVGPVMDDAA PEDSASPVSQ QRASQEQRAS QEPFSPAEDV METDLLEGLA ANQDRPSKML 
    MDRPTQSNIG IQTVDHSLCA PETVSAATQT VKSVCEQGTS TAEQNSGKQD ATVQTERGSG 
    EKPASAPVDD TESLHSQGEE EFEMPQPPHG HVLHRHMRTI REVRTLVTRV ITDVYYVDGT 
    EVERKVTEET EEPIVECQEC ETEVSPSQTG GSSGDLGDIS SFSSKASSSH HTSSGTSLSA 
    IHSSGSSGRG AGPLKGKASG TEAADFALPS SRGGPGKLSP RKGISQTGAP VCEEDGDAGL 
    GIRQGGKAPV TPRGRGRRGR PPSRTTGTRE TVVSGPLGVE DISPSMSPDD KSFTRIMPRV 
    PDSTKRTDAS SSTLRRSDSP EIPFQAATGS SDGLDSSSSG NSFVGLRVVA KWSSNGYFYS 
    GKITRDVGAG KYKLLFDDGY ECDVLGKDIL LCDPIPLDTE VTALSEDEYF SAGVVKGHRK 
    ESGELYYSIE KEGQRKWYKR MAVILSLEQG NRLREQYGLG PYEAVTPLTK AADISLDNLV 
    EGKRKRRSNI SSPVTPTAAS SSSTTPTRKA TESPRASTGV PSGKRKLPTS EEERSPAKRG 
    RKSATVKPGT VGAAEFVSPC ETGDNIGEPS VLEEPRGPLP LNKTLFLGYA FLLTMATTSD 
    KLASRSKLLD GPTGSSEEEE EFLEIPPFNK QYTECQLRAG AGYILEDFNE AQCNTAYQCL 
    LIADQHCRTR KYFLCLASGI PCVSHVWVHD SCHANQLQNY RNYLLPAGYS LEEQRILDWQ 
    PRENPFQNLK VLLVSDQQQN FLELWSEILM TGGAASVKQH HSSAHNKDIA LGVFDVVVTD 
    PSCPASVLKC AEALQLPVVS QEWVIQCLIV GERIGFKQHP KYKHDYVSH

Genular Protein ID: 3050312082

Symbol: Q8BZ87_MOUSE

Name: N/A

UniProtKB Accession Codes:

Database IDs:

Citations:

PubMed ID: 10349636

Title: High-efficiency full-length cDNA cloning.

PubMed ID: 10349636

DOI: 10.1016/S0076-6879(99)03004-9

PubMed ID: 11042159

Title: Normalization and subtraction of cap-trapper-selected cDNAs to prepare full-length cDNA libraries for rapid discovery of new genes.

PubMed ID: 11042159

DOI: 10.1101/gr.145100

PubMed ID: 11076861

Title: RIKEN integrated sequence analysis (RISA) system--384-format sequencing pipeline with 384 multicapillary sequencer.

PubMed ID: 11076861

DOI: 10.1101/gr.152600

PubMed ID: 11217851

Title: Functional annotation of a full-length mouse cDNA collection.

PubMed ID: 11217851

DOI: 10.1038/35055500

PubMed ID: 12466851

Title: Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs.

PubMed ID: 12466851

DOI: 10.1038/nature01266

PubMed ID: 16141073

Title: Antisense Transcription in the Mammalian Transcriptome.

PubMed ID: 16141073

DOI: 10.1126/science.1112009

Sequence Information:

  • Length: 613
  • Mass: 67135
  • Checksum: 7B551AC25F27F80A
  • Sequence:
  • KLSPRKGISQ TGAPVCEEDG DAGLGIRQGG KAPVTPRGRG RRGRPPSRTT GTRETVVSGP 
    LGVEDISPSM SPDDKSFTRI MPRVPDSTKR TDASSSTLRR SDSPEIPFQA ATGSSDGLDS 
    SSSGNSFVGL RVVAKWSSNG YFYSGKITRD VGAGKYKLLF DDGYECDVLG KDILLCDPIP 
    LDTEVTALSE DEYFSAGVVK GHRKESGELY YSIEKEGQRK WYKRMAVILS LEQGNRLREQ 
    YGLGPYEAVT PLTKAADISL DNLVEGKRKR RSNISSPVTP TAASSSCTTP TRKATESPRA 
    STGVPSGKRK LPTSEEERSP AKRGRKSATV KPGTVGAAEF VSPCETGDNI GEPSVLEEPR 
    GPLPLNKTLF LGYAFLLTMA TTSDKLASRS KLLDGPTGSS EEEEEFLEIP PFNKQYTECQ 
    LRAGAGYILE DFNEAQCNTA YQCLLIADQH CRTRKYFLCL ASGIPCVSHV WVHDSCHANQ 
    LQNYRNYLLP AGYSLEEQRI LDWQPRENPF QNLKVLLVSD QQQNFLELWS EILMTGGAAS 
    VKQHHSSAHN KDIALGVFDV VVTDPSCPAS VLKCAEALQL PVVSQEWVIQ CLIVGERIGF 
    KQHPKYKHDY VSH

Genular Protein ID: 2770229988

Symbol: A0A5H1ZRL7_MOUSE

Name: N/A

UniProtKB Accession Codes:

Database IDs:

Citations:

PubMed ID: 19468303

Title: Lineage-specific biology revealed by a finished genome assembly of the mouse.

PubMed ID: 19468303

DOI: 10.1371/journal.pbio.1000112

PubMed ID: 21750661

Title: Modernizing reference genome assemblies.

PubMed ID: 21750661

Sequence Information:

  • Length: 1919
  • Mass: 207653
  • Checksum: EA89E14E66663A01
  • Sequence:
  • MPGEQMDPTG SQLDSDFSQQ DTPCLIIEDS QPESQVLEED AGSHFSVLSR HLPNLQMHKE 
    NPVLDIVSNP EQSAVEQGDS NSSFNEHLKE KKASDPVESS HLGTSGSISQ VIERLPQPNR 
    TSSALAVTVE AASLPEEEKE EEELEEEKEG VGANAPGADS LAAEDSASSQ LGFGVLELSQ 
    SQDVEEHTVP YDVNQEHLQL VTTNSGSSPL SDVDASTAIK CEEQPTEDIA MIEQPSKDIP 
    VTVQPGKGIH VVEEQNLPLV RSEDRPSSPQ VSVAAVETKE QVPARELLEE GPQVQPSSEP 
    EVSSTQEDLF DQSSKTASDG CSTPSREEGG CSPVSTPATT LQLLQLSGQK PLVQESLSTN 
    SSDLVAPSPD AFRSTPFIVP SSPTEQGGRK DEPMDMSVIP VGGEPFQKLH DDEAMETEKP 
    LLPSQPAVSP QASTPVSRST PVFTPGSLPI PSQPEFSHDI FIPSPSLEEP SDDVKKGGGL 
    HSSSLTVECS KTSESEPKNF TDDLGLSMTG DSCKLMLSTS EYSQSSKMES LGSPRTEEDR 
    ENTQIDDTEP LSPVSNSKLP ADSENVLVTP SQDDQVEMSQ NVDKAKEDET EDRGDCKGRE 
    DAVAEDVCID LTCDSGSQAV PSPATRSEAL SSVLDQEEAM DTKEHHPEEG FSGSEVEEVP 
    ETPCGSHREE PKEEPMESIP LHLSLTETQS EALCLQKEAP KEECPEAMEV ETSVISIDSP 
    QKLQVLDQEL EHKDPDTWEE ATSEDSSVVI VDVKEPSPRA DVSCEPLEEV EKCSDSQSWE 
    GVAPEEEPCA ENRLDTPEEK RIECDGDSKA ETTEKDAVTE DSPQPPLPSV RDEPVRPDQE 
    TQQPQVQEKE SPVTVDAEVA DDKQLGPEGA CQQLEKAPAC ASQSFCESSS ETPFHFTLPK 
    EGDIIPPLTG ATPPLIGHLK LEPKRHSTPI GISNYPESTI ATSDVTSESM VEINDPLLGN 
    EKGDSESAPE MDGKLSLKMK LVSPETEASE ESLQFSLEKP TTAERKNGST AIAEPVASLQ 
    KPVPVFGCIY EAQQEKEAQS EAPPSAPDRA NLLHFPSAQE EDKERPDVTP KLRQSEQPVK 
    PVGPVMDDAA PEDSASPVSQ QRASQEQRAS QEPFSPAEDV METDLLEGLA ANQDRPSKML 
    MDRPTQSNIG IQTVDHSLCA PETVSAATQT VKSVCEQGTS TAEQNSGKQD ATVQTERGSG 
    EKPASAPVDD TESLHSQGEE EFEMPQPPHG HVLHRHMRTI REVRTLVTRV ITDVYYVDGT 
    EVERKVTEET EEPIVECQEC ETEVSPSQTG GSSGDLGDIS SFSSKASSSH HTSSGTSLSA 
    IHSSGSSGRG AGPLKGKASG TEAADFALPS SRGGPGKLRE TVVSGPLGVE DISPSMSPDD 
    KSFTRIMPRV PDSTKRTDAS SSTLRRSDSP EIPFQAATGS SDGLDSSSSG NSFVGLRVVA 
    KWSSNGYFYS GKITRDVGAG KYKLLFDDGY ECDVLGKDIL LCDPIPLDTE VTALSEDEYF 
    SAGVVKGHRK ESGELYYSIE KEGQRKWYKR MAVILSLEQG NRLREQYGLG PYEAVTPLTK 
    AADISLDNLV EGKRKRRSNI SSPVTPTAAS SSSTTPTRKA TESPRASTGV PSGKRKLPTS 
    EEERSPAKRG RKSATVKPGT VGAAEFVSPC ETGDNIGEPS VLEEPRGPLP LNKTLFLGYA 
    FLLTMATTSD KLASRSKLLD GPTGSSEEEE EFLEIPPFNK QYTECQLRAG AGYILEDFNE 
    AQCNTAYQCL LIADQHCRTR KYFLCLASGI PCVSHVWVHD SCHANQLQNY RNYLLPAGYS 
    LEEQRILDWQ PRENPFQNLK VLLVSDQQQN FLELWSEILM TGGAASVKQH HSSAHNKDIA 
    LGVFDVVVTD PSCPASVLKC AEALQLPVVS QEWVIQCLIV GERIGFKQHP KYKHDYVSH

Genular Protein ID: 1218584742

Symbol: Q3V1P7_MOUSE

Name: N/A

UniProtKB Accession Codes:

Database IDs:

Citations:

PubMed ID: 10349636

Title: High-efficiency full-length cDNA cloning.

PubMed ID: 10349636

DOI: 10.1016/S0076-6879(99)03004-9

PubMed ID: 11042159

Title: Normalization and subtraction of cap-trapper-selected cDNAs to prepare full-length cDNA libraries for rapid discovery of new genes.

PubMed ID: 11042159

DOI: 10.1101/gr.145100

PubMed ID: 11076861

Title: RIKEN integrated sequence analysis (RISA) system--384-format sequencing pipeline with 384 multicapillary sequencer.

PubMed ID: 11076861

DOI: 10.1101/gr.152600

PubMed ID: 11217851

Title: Functional annotation of a full-length mouse cDNA collection.

PubMed ID: 11217851

DOI: 10.1038/35055500

PubMed ID: 12466851

Title: Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs.

PubMed ID: 12466851

DOI: 10.1038/nature01266

PubMed ID: 16141073

Title: Antisense Transcription in the Mammalian Transcriptome.

PubMed ID: 16141073

DOI: 10.1126/science.1112009

Sequence Information:

  • Length: 689
  • Mass: 74266
  • Checksum: D37BB7DB82A7967B
  • Sequence:
  • ETEVSPSQTG GSSGDLGDIS SFSSKASSSH HTSSGTSLSA IHSSGSSGRG AGPLKGKASG 
    TEAADFALPS SRGGPGKLSP RKGISQTGAP VCEEDGDAGL GIRQGGKAPV TPRGRGRRGR 
    PPSRTTGTRE TVVSGPLGVE DISPSMSPDD KSFTRIMPRV PDSTKRTDAS SSTLRRSDSP 
    EIPFQAATGS SDGLDSSSSG NSFVGLRVVA KWSSNGYFYS GKITRDVGAG KYKLLFDDGY 
    ECDVLGKDIL LCDPIPLDTE VTALSEDEYF SAGVVKGHRK ESGELYYSIE KEGQRKWYKR 
    MAVILSLEQG NRLREQYGLG PYEAVTPLTK AADISLDNLV EGKRKRRSNI SSPVTPTAAS 
    SSSTTPTRKA TESPRASTGV PSGKRKLPTS EEERSPAKRG RKSATVKPGT VGAAEFVSPC 
    ETGDNIGEPS VLEEPRGPLP LNKTLFLGYA FLLTMATTSD KLASRSKLLD GPTGSSEEEE 
    EFLEIPPFNK QYTECQLRAG AGYILEDFNE AQCNTAYQCL LIADQHCRTR KYFLCLASGI 
    PCVSHVWVHD SCHANQLQNY RNYLLPAGYS LEEQRILDWQ PRENPFQNLK VLLVSDQQQN 
    FLELWSEILM TGGAASVKQH HSSAHNKDIA LGVFDVVVTD PSCPASVLKC AEALQLPVVS 
    QEWVIQCLIV GERIGFKQHP KYKHDYVSH

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.