Pla2g7 | ENSMUSG00000023913 | NCBI 27226

Details for: Pla2g7

Gene ID: 27226

Symbol: Pla2g7

Ensembl ID: ENSMUSG00000023913

Description: phospholipase A2, group VII (platelet-activating factor acetylhydrolase, plasma)

Associated with

Metabolism of proteins
(R-MMU-392499)
Peptide hormone metabolism
(R-MMU-2980736)
Synthesis, secretion, and deacylation of ghrelin
(R-MMU-422085)
1-alkyl-2-acetylglycerophosphocholine esterase activity
(GO:0003847)
Calcium-independent phospholipase a2 activity
(GO:0047499)
Extracellular space
(GO:0005615)
High-density lipoprotein particle
(GO:0034364)
Inflammatory response
(GO:0006954)
Lipid oxidation
(GO:0034440)
Low-density lipoprotein particle
(GO:0034362)
Low-density lipoprotein particle remodeling
(GO:0034374)
Phosphatidylcholine catabolic process
(GO:0034638)
Phospholipid binding
(GO:0005543)
Plasma lipoprotein particle oxidation
(GO:0034441)
Platelet activating factor catabolic process
(GO:0062234)
Platelet activating factor metabolic process
(GO:0046469)
Positive regulation of monocyte chemotaxis
(GO:0090026)

Other Information

Proteins

Platelet-activating factor acetylhydrolase

Genular Protein ID: 2873891668

Symbol: PAFA_MOUSE

Name: Platelet-activating factor acetylhydrolase

UniProtKB Accession Codes:

Q60963 Q8BKM3 Q921T4

Database IDs:

Citations:

PubMed ID: 7592717

Title: Plasma platelet-activating factor acetylhydrolase is a secreted phospholipase A2 with a catalytic triad.

PubMed ID: 7592717

DOI: 10.1074/jbc.270.43.25481

PubMed ID: 16141072

Title: The transcriptional landscape of the mammalian genome.

PubMed ID: 16141072

DOI: 10.1126/science.1112014

PubMed ID: 19468303

Title: Lineage-specific biology revealed by a finished genome assembly of the mouse.

PubMed ID: 19468303

DOI: 10.1371/journal.pbio.1000112

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 10066756

Title: Molecular basis of the interaction between plasma platelet-activating factor acetylhydrolase and low density lipoprotein.

PubMed ID: 10066756

DOI: 10.1074/jbc.274.11.7018

PubMed ID: 18434304

Title: Identification of a domain that mediates association of platelet-activating factor acetylhydrolase with high density lipoprotein.

PubMed ID: 18434304

DOI: 10.1074/jbc.m802394200

PubMed ID: 20531249

Title: Dual roles of endogenous platelet-activating factor acetylhydrolase in a murine model of necrotizing enterocolitis.

PubMed ID: 20531249

DOI: 10.1203/pdr.0b013e3181eb2efe

Sequence Information:

Length: 440
Mass: 49258
Checksum: 17C8B4D28F1ADC94
Sequence:

MVPLKLQALF CLLCCLPWVH PFHWQDTSSF DFRPSVMFHK LQSVMSAAGS GHSKIPKGNG 
SYPVGCTDLM FGYGNESVFV RLYYPAQDQG RLDTVWIPNK EYFLGLSIFL GTPSIVGNIL 
HLLYGSLTTP ASWNSPLRTG EKYPLIVFSH GLGAFRTIYS AIGIGLASNG FIVATVEHRD 
RSASATYFFE DQVAAKVENR SWLYLRKVKQ EESESVRKEQ VQQRAIECSR ALSAILDIEH 
GDPKENVLGS AFDMKQLKDA IDETKIALMG HSFGGATVLQ ALSEDQRFRC GVALDPWMYP 
VNEELYSRTL QPLLFINSAK FQTPKDIAKM KKFYQPDKER KMITIKGSVH QNFDDFTFVT 
GKIIGNKLTL KGEIDSRVAI DLTNKASMAF LQKHLGLQKD FDQWDPLVEG DDENLIPGSP 
FDAVTQVPAQ QHSPGSQTQN

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: Pla2g7

Associated with

Other Information

Plasma platelet-activating factor acetylhydrolase is a secreted phospholipase A2 with a catalytic triad. PubMed ID: 7592717

The transcriptional landscape of the mammalian genome. PubMed ID: 16141072

Lineage-specific biology revealed by a finished genome assembly of the mouse. PubMed ID: 19468303

The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). PubMed ID: 15489334

Molecular basis of the interaction between plasma platelet-activating factor acetylhydrolase and low density lipoprotein. PubMed ID: 10066756

Identification of a domain that mediates association of platelet-activating factor acetylhydrolase with high density lipoprotein. PubMed ID: 18434304

Dual roles of endogenous platelet-activating factor acetylhydrolase in a murine model of necrotizing enterocolitis. PubMed ID: 20531249