Details for: Phlda3

Gene ID: 27280

Symbol: Phlda3

Ensembl ID: ENSMUSG00000041801

Description: pleckstrin homology like domain, family A, member 3

Associated with

  • Cytoplasm
    (GO:0005737)
  • Intrinsic apoptotic signaling pathway in response to dna damage by p53 class mediator
    (GO:0042771)
  • Negative regulation of phosphatidylinositol 3-kinase/protein kinase b signal transduction
    (GO:0051898)
  • Phosphatidylinositol-3,4,5-trisphosphate binding
    (GO:0005547)
  • Phosphatidylinositol-3,4-bisphosphate binding
    (GO:0043325)
  • Phosphatidylinositol-3,5-bisphosphate binding
    (GO:0080025)
  • Phosphatidylinositol-3-phosphate binding
    (GO:0032266)
  • Phosphatidylinositol-4,5-bisphosphate binding
    (GO:0005546)
  • Phosphatidylinositol-5-phosphate binding
    (GO:0010314)
  • Plasma membrane
    (GO:0005886)
  • Positive regulation of apoptotic process
    (GO:0043065)

Other Information

Genular Protein ID: 4182395243

Symbol: PHLA3_MOUSE

Name: Pleckstrin homology-like domain family A member 3

UniProtKB Accession Codes:

Q9WV95

Database IDs:

AGR 1 AlphaFoldDB 1 Antibodypedia 1 Bgee 1 BioGRID-ORCS 1 CCDS 1 CDD 1 CTD 1 DNASU 1 EMBL 3 Ensembl 1 GO 11 Gene3D 1 GeneTree 1 HOGENOM 1 InParanoid 1 IntAct 1 InterPro 3 KEGG 1 MGI 1 MINT 1 NCBI Taxonomy 1 OMA 1 OrthoDB 1 PANTHER 2 PRO 1 PaxDb 1 PeptideAtlas 1 Pfam 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 1 Pumba 1 RNAct 1 RefSeq 1 SMART 1 SMR 1 STRING 1 SUPFAM 1 TreeFam 1 UCSC 1 VEuPathDB 1 eggNOG 1 iPTMnet 1

Citations:

PubMed ID: 10594239

Title: A novel pleckstrin homology-related gene family defined by Ipl/Tssc3, TDAG51, and Tih1: tissue-specific expression, chromosomal location, and parental imprinting.

PubMed ID: 10594239

DOI: 10.1007/s003359901182

PubMed ID: 16141072

Title: The transcriptional landscape of the mammalian genome.

PubMed ID: 16141072

DOI: 10.1126/science.1112014

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 12374806

Title: Phosphoinositide binding by the pleckstrin homology domains of Ipl and Tih1.

PubMed ID: 12374806

DOI: 10.1074/jbc.m206497200

PubMed ID: 12032310

Title: Placental overgrowth in mice lacking the imprinted gene Ipl.

PubMed ID: 12032310

DOI: 10.1073/pnas.122039999

PubMed ID: 21183079

Title: A tissue-specific atlas of mouse protein phosphorylation and expression.

PubMed ID: 21183079

DOI: 10.1016/j.cell.2010.12.001

Sequence Information:

  • Length: 125
  • Mass: 13719
  • Checksum: 53E44E6A29C036A4
  • Sequence:
    • MTAAATVLKE GVLEKRSGGL LQLWKRKRCV LTERGLQLFE AKGTGGRPKE LSFARIKAVE 
CVESTGRHIY FTLVTEGGGE IDFRCPLEDP GWNAQITLGL VKFKNQQAIQ TVRARQSLGT 
GTLVS

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.