Sytl4 | ENSMUSG00000031255 | NCBI 27359

Details for: Sytl4

Gene ID: 27359

Symbol: Sytl4

Ensembl ID: ENSMUSG00000031255

Description: synaptotagmin-like 4

Associated with

Hemostasis
(R-MMU-109582)
Platelet activation, signaling and aggregation
(R-MMU-76002)
Platelet degranulation
(R-MMU-114608)
Response to elevated platelet cytosolic ca2+
(R-MMU-76005)
Apical plasma membrane
(GO:0016324)
Endosome
(GO:0005768)
Exocytic vesicle
(GO:0070382)
Exocytosis
(GO:0006887)
Insulin secretion
(GO:0030073)
Intracellular protein transport
(GO:0006886)
Lysosome localization
(GO:0032418)
Multivesicular body sorting pathway
(GO:0071985)
Negative regulation of insulin secretion
(GO:0046676)
Neurexin family protein binding
(GO:0042043)
Phospholipid binding
(GO:0005543)
Plasma membrane
(GO:0005886)
Plasma membrane repair
(GO:0001778)
Positive regulation of exocytosis
(GO:0045921)
Positive regulation of protein secretion
(GO:0050714)
Protein binding
(GO:0005515)
Regulation of plasma membrane repair
(GO:1905684)
Secretory granule
(GO:0030141)
Small gtpase binding
(GO:0031267)
Transport vesicle membrane
(GO:0030658)
Zinc ion binding
(GO:0008270)

Other Information

Proteins

Synaptotagmin-like protein 4

Genular Protein ID: 3174422241

Symbol: SYTL4_MOUSE

Name: Synaptotagmin-like protein 4

UniProtKB Accession Codes:

Q9R0Q1 B1AVI8 B1AVI9 Q8R321 Q9R0Q0

Database IDs:

Citations:

PubMed ID: 10497219

Title: Novel rabphilin-3-like protein associates with insulin-containing granules in pancreatic beta cells.

PubMed ID: 10497219

DOI: 10.1074/jbc.274.40.28542

PubMed ID: 16141072

Title: The transcriptional landscape of the mammalian genome.

PubMed ID: 16141072

DOI: 10.1126/science.1112014

PubMed ID: 19468303

Title: Lineage-specific biology revealed by a finished genome assembly of the mouse.

PubMed ID: 19468303

DOI: 10.1371/journal.pbio.1000112

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 11956164

Title: Involvement of Rab27b in the regulated secretion of pituitary hormones.

PubMed ID: 11956164

DOI: 10.1210/endo.143.5.8823

PubMed ID: 11773082

Title: The Slp homology domain of synaptotagmin-like proteins 1-4 and Slac2 functions as a novel Rab27A binding domain.

PubMed ID: 11773082

DOI: 10.1074/jbc.m112414200

PubMed ID: 12101244

Title: Granuphilin modulates the exocytosis of secretory granules through interaction with syntaxin 1a.

PubMed ID: 12101244

DOI: 10.1128/mcb.22.15.5518-5526.2002

PubMed ID: 12590134

Title: Slp4-a/granuphilin-a inhibits dense-core vesicle exocytosis through interaction with the GDP-bound form of Rab27A in PC12 cells.

PubMed ID: 12590134

DOI: 10.1074/jbc.m213090200

PubMed ID: 17242355

Title: Large-scale phosphorylation analysis of mouse liver.

PubMed ID: 17242355

DOI: 10.1073/pnas.0609836104

PubMed ID: 21183079

Title: A tissue-specific atlas of mouse protein phosphorylation and expression.

PubMed ID: 21183079

DOI: 10.1016/j.cell.2010.12.001

PubMed ID: 23798443

Title: Structural basis of cargo recognitions for class V myosins.

PubMed ID: 23798443

DOI: 10.1073/pnas.1306768110

Sequence Information:

Length: 673
Mass: 76021
Checksum: 2AC218E2A4BE4C8D
Sequence:

MSEILDLSFL SEMERDLILG VLQRDEELRK ADEKRIRRLK NELLEIKRKG AKRGSQHYSD 
RTCARCQEGL GRLIPKSSTC VGCNHLVCRE CRVLESNGSW RCKVCSKEIE LKKATGDWFY 
DQKVNRFDYR TGSEIIRMSL RQKPAVNKRE TAGQSLLQQT QMGDIWPGRR IIQEQQQREQ 
SVLFEVPKTR SGKSALEAES ESLDSYTADS DSTSRRDSLD KSGLFPEWKK MSAPKSQVEK 
EIPPGNQNAV CGDEGDMVFK KNTKKVLRPS EYTKSVIDLR PEDVAQESGI LGDRSKSVPG 
LSVDMEEEEE EEEDIDHLVK LHRQKLARGS MQSGSSMSTL GSIMSIYSEA GDFGNISVTG 
KIAFSLKFEQ KTQTLVIHVK ECHQLAYADE AKKRSNPYVK TYLLPDKSRQ GKRKTSIKRD 
TINPLYDETF RYEISESLLA QRTLQFSVWH HGRFGRNTFL GEAEVHMDSW KLDKKLDHCL 
PLHGKISTES SPGLPAHKGE LVVSLKYIPA SKLPVGGDRK KSKGGEGGEL QVWIKEAKNL 
TAAKSGGTSD SFVKGYLLPM RNKASKRKTP VMKKTLSPHY NHTFVYNGVR LEDLQHMCLE 
LTVWDREPLA SNDFLGGVRL GVGTGISNGE VVDWMDSTGE EVSLWQKMRQ YPGSWAEGTL 
QLRSSMVKQK LGV

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: Sytl4

Associated with

Other Information

Novel rabphilin-3-like protein associates with insulin-containing granules in pancreatic beta cells. PubMed ID: 10497219

The transcriptional landscape of the mammalian genome. PubMed ID: 16141072

Lineage-specific biology revealed by a finished genome assembly of the mouse. PubMed ID: 19468303

The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). PubMed ID: 15489334

Involvement of Rab27b in the regulated secretion of pituitary hormones. PubMed ID: 11956164

The Slp homology domain of synaptotagmin-like proteins 1-4 and Slac2 functions as a novel Rab27A binding domain. PubMed ID: 11773082

Granuphilin modulates the exocytosis of secretory granules through interaction with syntaxin 1a. PubMed ID: 12101244

Slp4-a/granuphilin-a inhibits dense-core vesicle exocytosis through interaction with the GDP-bound form of Rab27A in PC12 cells. PubMed ID: 12590134

Large-scale phosphorylation analysis of mouse liver. PubMed ID: 17242355

A tissue-specific atlas of mouse protein phosphorylation and expression. PubMed ID: 21183079

Structural basis of cargo recognitions for class V myosins. PubMed ID: 23798443