Details for: Prmt5

Gene ID: 27374

Symbol: Prmt5

Ensembl ID: ENSMUSG00000023110

Description: protein arginine N-methyltransferase 5

Associated with

Other Information

Genular Protein ID: 3024459659

Symbol: ANM5_MOUSE

Name: Protein arginine N-methyltransferase 5

UniProtKB Accession Codes:

Database IDs:

Citations:

PubMed ID: 16141072

Title: The transcriptional landscape of the mammalian genome.

PubMed ID: 16141072

DOI: 10.1126/science.1112014

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 10531356

Title: The human homologue of the yeast proteins Skb1 and Hsl7p interacts with Jak kinases and contains protein methyltransferase activity.

PubMed ID: 10531356

DOI: 10.1074/jbc.274.44.31531

PubMed ID: 15485929

Title: Human SWI/SNF-associated PRMT5 methylates histone H3 arginine 8 and negatively regulates expression of ST7 and NM23 tumor suppressor genes.

PubMed ID: 15485929

DOI: 10.1128/mcb.24.21.9630-9645.2004

PubMed ID: 16699504

Title: Blimp1 associates with Prmt5 and directs histone arginine methylation in mouse germ cells.

PubMed ID: 16699504

DOI: 10.1038/ncb1413

PubMed ID: 19584108

Title: Proteomic analysis of murine Piwi proteins reveals a role for arginine methylation in specifying interaction with Tudor family members.

PubMed ID: 19584108

DOI: 10.1101/gad.1814809

PubMed ID: 21183079

Title: A tissue-specific atlas of mouse protein phosphorylation and expression.

PubMed ID: 21183079

DOI: 10.1016/j.cell.2010.12.001

PubMed ID: 19858291

Title: Friend of Prmt1, a novel chromatin target of protein arginine methyltransferases.

PubMed ID: 19858291

DOI: 10.1128/mcb.00645-09

PubMed ID: 21917714

Title: Protein arginine methyltransferase 5 regulates ERK1/2 signal transduction amplitude and cell fate through CRAF.

PubMed ID: 21917714

DOI: 10.1126/scisignal.2001936

PubMed ID: 22872859

Title: Five friends of methylated chromatin target of protein-arginine-methyltransferase[prmt]-1 (chtop), a complex linking arginine methylation to desumoylation.

PubMed ID: 22872859

DOI: 10.1074/mcp.m112.017194

PubMed ID: 22193545

Title: The histone- and PRMT5-associated protein COPR5 is required for myogenic differentiation.

PubMed ID: 22193545

DOI: 10.1038/cdd.2011.193

PubMed ID: 23133559

Title: Role of type II protein arginine methyltransferase 5 in the regulation of Circadian Per1 gene.

PubMed ID: 23133559

DOI: 10.1371/journal.pone.0048152

PubMed ID: 28263986

Title: TDRD6 mediates early steps of spliceosome maturation in primary spermatocytes.

PubMed ID: 28263986

DOI: 10.1371/journal.pgen.1006660

Sequence Information:

  • Length: 637
  • Mass: 72680
  • Checksum: E8014CA172B30543
  • Sequence:
  • MAAMAVGGAG GSRVSSGRDL NCVPEIADTL GAVAKQGFDF LCMPVFHPRF KREFIQEPAK 
    NRPGPQTRSD LLLSGRDWNT LIVGKLSPWI HPDSKVEKIR RNSEAAMLQE LNFGAYLGLP 
    AFLLPLNQED NTNLARVLTN HIHTGHHSSM FWMRVPLVAP EDLRDDVIAN APTTHTEEYS 
    GEEKTWMWWH NFRTLCDYSK RIAVALEIGA DLPSNHVIDR WLGEPIKAAI LPTSIFLTNK 
    KGFPVLSKVQ QRLIFRLLKL EVQFIITGTN HHSEKEFCSY LQYLEYLSQN RPPPNAYELF 
    AKGYEDYLQS PLQPLMDNLE SQTYEVFEKD PIKYSQYQQA IYKCLLDRVP EEEKETNVQV 
    LMVLGAGRGP LVNASLRAAK QAERRIRLYA VEKNPNAVVT LENWQFEEWG SQVTVVSSDM 
    REWVAPEKAD IIVSELLGSF ADNELSPECL DGAQHFLKDD GVSIPGEYTS FLAPISSSKL 
    YNEVRACREK DRDPEAQFEM PYVVRLHNFH QLSAPKPCFT FSHPNRDPMI DNNRYCTLEF 
    PVEVNTVLHG FAGYFETVLY RDITLSIRPE THSPGMFSWF PIFFPIKQPI TVHEGQNICV 
    RFWRCSNSKK VWYEWAVTAP VCSSIHNPTG RSYTIGL

Genular Protein ID: 3785823061

Symbol: A0A0R4J049_MOUSE

Name: N/A

UniProtKB Accession Codes:

Database IDs:

Citations:

PubMed ID: 19468303

Title: Lineage-specific biology revealed by a finished genome assembly of the mouse.

PubMed ID: 19468303

DOI: 10.1371/journal.pbio.1000112

PubMed ID: 21183079

Title: A tissue-specific atlas of mouse protein phosphorylation and expression.

PubMed ID: 21183079

DOI: 10.1016/j.cell.2010.12.001

PubMed ID: 21750661

Title: Modernizing reference genome assemblies.

PubMed ID: 21750661

Sequence Information:

  • Length: 637
  • Mass: 72738
  • Checksum: F0E986699B0B42C0
  • Sequence:
  • MAAMAVGGAG GSRVSSGRDL NCVPEIADTL GAVAKQGFDF LCMPVFHPRF KREFIQEPAK 
    NRPGPQTRSD LLLSGRDWNT LIVGKLSPWI HPDSKVEKIR RNSEAAMLQE LNFGAYLGLP 
    AFLLPLNQED NTNLARVLTN HIHTGHHSSM FWMRVPLVAP EDLRDDVIEN APTTHTEEYS 
    GEEKTWMWWH NFRTLCDYSK RIAVALEIGA DLPSNHVIDR WLGEPIKAAI LPTSIFLTNK 
    KGFPVLSKVQ QRLIFRLLKL EVQFIITGTN HHSEKEFCSY LQYLEYLSQN RPPPNAYELF 
    AKGYEDYLQS PLQPLMDNLE SQTYEVFEKD PIKYSQYQQA IYKCLLDRVP EEEKETNVQV 
    LMVLGAGRGP LVNASLRAAK QAERRIRLYA VEKNPNAVVT LENWQFEEWG SQVTVVSSDM 
    REWVAPEKAD IIVSELLGSF ADNELSPECL DGAQHFLKDD GVSIPGEYTS FLAPISSSKL 
    YNEVRACREK DRDPEAQFEM PYVVRLHNFH QLSAPKPCFT FSHPNRDPMI DNNRYCTLEF 
    PVEVNTVLHG FAGYFETVLY RDITLSIRPE THSPGMFSWF PIFFPIKQPI TVHEGQNICV 
    RFWRCSNSKK VWYEWAVTAP VCSSIHNPTG RSYTIGL

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.