Details for: Sh2d3c

Gene ID: 27387

Symbol: Sh2d3c

Ensembl ID: ENSMUSG00000059013

Description: SH2 domain containing 3C

Associated with

Other Information

Genular Protein ID: 2883819214

Symbol: SH2D3_MOUSE

Name: SH2 domain-containing protein 3C

UniProtKB Accession Codes:

Database IDs:

Citations:

PubMed ID: 10542222

Title: A novel signaling intermediate, SHEP1, directly couples Eph receptors to R-Ras and Rap1A.

PubMed ID: 10542222

DOI: 10.1074/jbc.274.45.31941

PubMed ID: 10692442

Title: Chat, a Cas/HEF1-associated adaptor protein that integrates multiple signaling pathways.

PubMed ID: 10692442

DOI: 10.1074/jbc.275.9.6404

PubMed ID: 12486027

Title: A novel hematopoietic adaptor protein, Chat-H, positively regulates T cell receptor-mediated interleukin-2 production by Jurkat cells.

PubMed ID: 12486027

DOI: 10.1074/jbc.m207942200

PubMed ID: 16141072

Title: The transcriptional landscape of the mammalian genome.

PubMed ID: 16141072

DOI: 10.1126/science.1112014

PubMed ID: 19468303

Title: Lineage-specific biology revealed by a finished genome assembly of the mouse.

PubMed ID: 19468303

DOI: 10.1371/journal.pbio.1000112

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 15272013

Title: SHEP1 function in cell migration is impaired by a single amino acid mutation that disrupts association with the scaffolding protein cas but not with Ras GTPases.

PubMed ID: 15272013

DOI: 10.1074/jbc.m402929200

PubMed ID: 17174122

Title: The hematopoietic isoform of Cas-Hef1-associated signal transducer regulates chemokine-induced inside-out signaling and T cell trafficking.

PubMed ID: 17174122

DOI: 10.1016/j.immuni.2006.09.014

PubMed ID: 19144319

Title: The phagosomal proteome in interferon-gamma-activated macrophages.

PubMed ID: 19144319

DOI: 10.1016/j.immuni.2008.11.006

PubMed ID: 21183079

Title: A tissue-specific atlas of mouse protein phosphorylation and expression.

PubMed ID: 21183079

DOI: 10.1016/j.cell.2010.12.001

PubMed ID: 20505138

Title: The adaptor protein Sh2d3c is critical for marginal zone B cell development and function.

PubMed ID: 20505138

DOI: 10.4049/jimmunol.1000096

PubMed ID: 20881139

Title: The SRC homology 2 domain protein Shep1 plays an important role in the penetration of olfactory sensory axons into the forebrain.

PubMed ID: 20881139

DOI: 10.1523/jneurosci.3289-10.2010

PubMed ID: 20956287

Title: SHEP1 partners with CasL to promote marginal zone B-cell maturation.

PubMed ID: 20956287

DOI: 10.1073/pnas.1007558107

Sequence Information:

  • Length: 854
  • Mass: 94323
  • Checksum: FA8FC2FDEAE32FF5
  • Sequence:
  • MTEMPKKTGR KFKFFKFKGL GSLSNLPRSF SLRRSSASAS IRSCPEPDTF EATQDDMVTL 
    PKSPPAYARS SDMYSHMGTM PRPNIKKAQK QQAVQKAQEV SRESHLVSRR LPEPPDLEAA 
    KEAGEGTEAL LEDTAPSAVE VDPMRELEDL TVDTEKEQVP GDVSPERTAA ELEAAGDYVK 
    FSKEKYILDS SPEKLHKELE EELKLSSTDL RSHAWYHGRI PREVSETLVQ RNGDFLIRDS 
    LTSLGDYVLT CRWHNQALHF KINKVVVKAG ESYTHIRYLF EQESFDHVPA LVRYHVGSRK 
    AVSEQSGAII YCPVNRTFPL RYLEASYGLS QGSSKTASPA SPSGSKGSHM KRRSITMTDG 
    LTTDKVTRSD GCPNSTSLPH PRDSIRNCAL SMDQIPDLHS PLSPISESPS SPAYSTVTRV 
    HAPSATPSTS AQPASPVARR SSEPQLCPGN TPKPPGESDR APHASPSHTL CKASPSPSLS 
    SYSDPDSGHY CQLQPPVRGS REQAAGETPR KARGSGERQK ELLENGVSDG EWGKTFTVPV 
    VEATSSFNLA TFQSQLIPKE NRPLEVALLR KVKELLSEVD ARTLARHVTK VDCLVARILG 
    VTKEMQTLMG VRWGMELLTL PHGRQLRLDL LERFHTMSIM LAVDILGCTG SAEERAALLH 
    KTIQLAAELR GTMGNMFSFA AVMGALEMAQ ISRLEQTWMT LRQRHTEGAI LYEKKLKPFL 
    KSLNEGKEGP PLSNTTFPHV LPFITLLECD SAPAEGPEPW GSTEHGVEVV LAHLEAARTV 
    AHHGGLYHTN AEVKLQGFQA RPELLEVFST EFQMRLLWGS QGANSSQAWR YEKFDKVLTA 
    LSHKLEPAIR SSEL

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.