Details for: Abca7
Associated with
Other Information
Genular Protein ID: 3879148525
Symbol: ABCA7_MOUSE
Name: ATP-binding cassette sub-family A member 7
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 11435699
Title: Comparative analysis of the promoter structure and genomic organization of the human and mouse ABCA7 gene encoding a novel ABCA transporter.
PubMed ID: 11435699
DOI: 10.1159/000056914
PubMed ID: 10708515
Title: Identification of 18 mouse ABC genes and characterization of the ABC superfamily in Mus musculus.
PubMed ID: 10708515
PubMed ID: 12917409
Title: ATP-binding cassette transporter A7 (ABCA7) binds apolipoprotein A-I and mediates cellular phospholipid but not cholesterol efflux.
PubMed ID: 12917409
PubMed ID: 16445568
Title: Acute digoxin loading reduces ABCA8A mRNA expression in the mouse liver.
PubMed ID: 16445568
PubMed ID: 15550377
Title: Abca7 null mice retain normal macrophage phosphatidylcholine and cholesterol efflux activity despite alterations in adipose mass and serum cholesterol levels.
PubMed ID: 15550377
PubMed ID: 16908670
Title: ATP-binding cassette transporter A7 enhances phagocytosis of apoptotic cells and associated ERK signaling in macrophages.
PubMed ID: 16908670
PubMed ID: 19144319
Title: The phagosomal proteome in interferon-gamma-activated macrophages.
PubMed ID: 19144319
PubMed ID: 21183079
Title: A tissue-specific atlas of mouse protein phosphorylation and expression.
PubMed ID: 21183079
PubMed ID: 20495215
Title: Helical apolipoproteins of high-density lipoprotein enhance phagocytosis by stabilizing ATP-binding cassette transporter A7.
PubMed ID: 20495215
DOI: 10.1194/jlr.m006049
PubMed ID: 26260791
Title: ATP-binding cassette transporter A7 (ABCA7) loss of function alters Alzheimer amyloid processing.
PubMed ID: 26260791
PubMed ID: 27472885
Title: ABCA7 Mediates Phagocytic Clearance of Amyloid-beta in the Brain.
PubMed ID: 27472885
DOI: 10.3233/jad-160456
PubMed ID: 27030769
Title: ABCA7 Deficiency Accelerates Amyloid-beta Generation and Alzheimer's Neuronal Pathology.
PubMed ID: 27030769
PubMed ID: 28091533
Title: ATP Binding Cassette Transporter ABCA7 Regulates NKT Cell Development and Function by Controlling CD1d Expression and Lipid Raft Content.
PubMed ID: 28091533
DOI: 10.1038/srep40273
Sequence Information:
- Length: 2159
- Mass: 236884
- Checksum: CD2BE3FE0D8B822B
- Sequence:
MALGTQLMLL LWKNYTYRRR QPIQLLVELL WPLFLFFILV AVRHSHPPLE HHECHFPNKP LPSAGTVPWL QGLVCNVNNS CFQHPTPGEK PGVLSNFKDS LISRLLADTR TVLGGHSIQD MLDALGKLIP VLRAVGGGAR PQESDQPTSQ GSVTKLLEKI LQRASLDPVL GQAQDSMRKF SDAIRDLAQE LLTLPSLMEL RALLRRPRGS AGSLELVSEA LCSTKGPSSP GGLSLNWYEA NQLNEFMGPE VAPALPDNSL SPACSEFVGT LDDHPVSRLL WRRLKPLILG KILFAPDTNF TRKLMAQVNQ TFEELALLRD LHELWGVLGP QIFNFMNDST NVAMLQRLLD VGGTGQRQQT PRAQKKLEAI KDFLDPSRGG YSWREAHADM GRLAGILGQM MECVSLDKLE AVPSEEALVS RALELLGERR LWAGIVFLSP EHPLDPSELS SPALSPGHLR FKIRMDIDDV TRTNKIRDKF WDPGPSADPF MDLRYVWGGF VYLQDLLEQA AVRVLGGGNS RTGLYLQQMP HPCYVDDVFL RVLSRSLPLF LTLAWIYSVA LTVKAVVREK ETRLRETMRA MGLSRAVLWL GWFLSCLGPF LVSAALLVLV LKLGNILPYS HPVVIFLFLA AFAVATVAQS FLLSAFFSRA NLAAACGGLA YFALYLPYVL CVAWRERLHL GGLLAASLLS PVAFGFGCES LALLEEQGDG AQWHNLGTGP AEDVFSLAQV SAFLLLDAVI YGLALWYLEA VCPGQYGIPE PWNFPFRRSY WCGPGPPKSS VLAPAPQDPK VLVEEPPLGL VPGVSIRGLK KHFRGCPQPA LQGLNLDFYE GHITAFLGHN GAGKTTTLSI LSGLFPPSSG SASILGHDVQ TNMAAIRPHL GICPQYNVLF DMLTVEEHVW FYGRLKGVSA AAMGPERERL IRDVGLTLKR DTQTRHLSGG MQRKLSVAIA FVGGSRVVIM DEPTAGVDPA SRRGIWELLL KYREGRTLIL STHHLDEAEL LGDRVAMVAG GSLCCCGSPL FLRRHLGCGY YLTLVKSSQS LVTHDAKGDS EDPRREKKSD GNGRTSDTAF TRGTSDKSNQ APAPGAVPIT PSTARILELV QQHVPGAQLV EDLPHELLLV LPYAGALDGS FAMVFQELDQ QLELLGLTGY GISDTNLEEI FLKVVEDAHR EGGDSRPQLH LRTCTPQPPT GPEASVLENG ELAPQGLAPN AAQVQGWTLT CQQLRALLHK RFLLARRSRR GLFAQVVLPA LFVGLALFFS LIVPPFGQYP PLQLSPAMYG PQVSFFSEDA PGDPNRMKLL EALLGEAGLQ EPSMQDKDAR GSECTHSLAC YFTVPEVPPD VASILASGNW TPESPSPACQ CSQPGARRLL PDCPAGAGGP PPPQAVAGLG EVVQNLTGRN VSDFLVKTYP SLVRRGLKTK KWVDEVRYGG FSLGGRDPDL PTGHEVVRTL AEIRALLSPQ PGNALDRILN NLTQWALGLD ARNSLKIWFN NKGWHAMVAF VNRANNGLLH ALLPSGPVRH AHSITTLNHP LNLTKEQLSE ATLIASSVDV LVSICVVFAM SFVPASFTLV LIEERITRAK HLQLVSGLPQ TLYWLGNFLW DMCNYLVAVC IVVFIFLAFQ QRAYVAPENL PALLLLLLLY GWSITPLMYP ASFFFSVPST AYVVLTCINL FIGINSSMAT FVLELLSDQN LQEVSRILKQ VFLIFPHFCL GRGLIDMVRN QAMADAFERL GDKQFQSPLR WDIIGKNLLA MMAQGPLFLL ITLLLQHRNR LLPQSKPRLL PPLGEEDEDV AQERERVTKG ATQGDVLVLR DLTKVYRGQR NPAVDRLCLG IPPGECFGLL GVNGAGKTST FRMVTGDTLP SSGEAVLAGH NVAQERSAAH RSMGYCPQSD AIFDLLTGRE HLELFARLRG VPEAQVAQTA LSGLVRLGLP SYADRPAGTY SGGNKRKLAT ALALVGDPAV VFLDEPTTGM DPSARRFLWN SLLSVVREGR SVVLTSHSME ECEALCTRLA IMVNGRFRCL GSSQHLKGRF GAGHTLTLRV PPDQPEPAIA FIRITFPGAE LREVHGSRLR FQLPPGGRCT LTRVFRELAA QGRAHGVEDF SVSQTTLEEV FLYFSKDQGE EEESSRQEAE EEEVSKPGRQ HPKRVSRFLE DPSSVETMI
Genular Protein ID: 3995951303
Symbol: E9Q6G4_MOUSE
Name: N/A
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 19144319
Title: The phagosomal proteome in interferon-gamma-activated macrophages.
PubMed ID: 19144319
PubMed ID: 19468303
Title: Lineage-specific biology revealed by a finished genome assembly of the mouse.
PubMed ID: 19468303
PubMed ID: 21183079
Title: A tissue-specific atlas of mouse protein phosphorylation and expression.
PubMed ID: 21183079
PubMed ID: 21750661
Title: Modernizing reference genome assemblies.
PubMed ID: 21750661
Sequence Information:
- Length: 2167
- Mass: 237749
- Checksum: 92834AD98550C08A
- Sequence:
MALGTQLMLL LWKNYTYRRR QPIQLLVELL WPLFLFFILV AVRHSHPPLE HHECHFPNKP LPSAGTVPWL QGLVCNVNNS CFQHPTPGEK PGVLSNFKDS LISRLLADTR TVLGGHSIQD MLDALGKLIP VLRAVGGGAR PQESDQPTSQ GSVTKLLEKI LQRASLDPVL GQAQDSMRKF SDAIRDLAQE LLTLPSLMEL RALLRRPRGS AGSLELVSEA LCSTKGPSSP GGLSLNWYEA NQLNEFMGPE VAPALPDNSL SPACSEFVGT LDDHPVSRLL WRRLKPLILG KILFAPDTNF TRKLMAQVNQ TFEELALLRD LHELWGVLGP QIFNFMNDST NVAMLQRLLD VGGTGQRQQT PRAQKKLEAI KDFLDPSRGG YSWREAHADM GRLAGILGQM MECVSLDKLE AVPSEEALVS RALELLGERR LWAGIVFLSP EHPLDPSELS SPALSPGHLR FKIRMDIDDV TRTNKIRDKF WDPGPSADPF MDLRYVWGGF VYLQDLLEQA AVRVLGGGNS RTGLYLQQMP HPCYVDDVFL RVLSRSLPLF LTLAWIYSVA LTVKAVVREK ETRLRETMRA MGLSRAVLWL GWFLSCLGPF LVSAALLVLV LKLGNILPYS HPVVIFLFLA AFAVATVAQS FLLSAFFSRA NLAAACGGLA YFALYLPYVL CVAWRERLHL GGLLAASLLS PVAFGFGCES LALLEEQGDG AQWHNLGTGP AEDVFSLAQV SAFLLLDAVI YGLALWYLEA VCPGQYGIPE PWNFPFRRSY WCGPGPPKSS VLAPAPQDPK VLVEEPPLGL VPGVSIRGLK KHFRGCPQPA LQGLNLDFYE GHITAFLGHN GAGKTTTLSI LSGLFPPSSG SASILGHDVQ TNMAAIRPHL GICPQYNVLF DMLTVEEHVW FYGRLKGVSA AAMGPERERL IRDVGLTLKR DTQTRHLSGG MQRKLSVAIA FVGGSRVVIM DEPTAGVDPA SRRGIWELLL KYREGRTLIL STHHLDEAEL LGDRVAMVAG GSLCCCGSPL FLRRHLGCGY YLTLVKSSQS LVTHDAKGDS EDPRREKKSD GNGRTSDTAF TRGTSDKSNQ APAPGAVPIT PSTARILELV QQHVPGAQLV EDLPHELLLV LPYAGALDGS FAMVFQELDQ QLELLGLTGY GISDTNLEEI FLKVVEDAHR EGGDSRPQLH LRTCTPQPPT GPEASVLENG ELAKLVLDPQ APQGLAPNAA QVQGWTLTCQ QLRALLHKRF LLARRSRRGL FAQVVLPALF VGLALFFSLI VPPFGQYPPL QLSPAMYGPQ VSFFSEDAPG DPNRMKLLEA LLGEAGLQEP SMQDKDARGS ECTHSLACYF TVPEVPPDVA SILASGNWTP ESPSPACQCS QPGARRLLPD CPAGAGGPPP PQAVAGLGEV VQNLTGRNVS DFLVKTYPSL VRRGLKTKKW VDEVRYGGFS LGGRDPDLPT GHEVVRTLAE IRALLSPQPG NALDRILNNL TQWALGLDAR NSLKIWFNNK GWHAMVAFVN RANNGLLHAL LPSGPVRHAH SITTLNHPLN LTKEQLSEAT LIASSVDVLV SICVVFAMSF VPASFTLVLI EERITRAKHL QLVSGLPQTL YWLGNFLWDM CNYLVAVCIV VFIFLAFQQR AYVAPENLPA LLLLLLLYGW SITPLMYPAS FFFSVPSTAY VVLTCINLFI GINSSMATFV LELLSDQNLQ EVSRILKQVF LIFPHFCLGR GLIDMVRNQA MADAFERLGD KQFQSPLRWD IIGKNLLAMM AQGPLFLLIT LLLQHRNRLL PQSKPRLLPP LGEEDEDVAQ ERERVTKGAT QGDVLVLRDL TKVYRGQRNP AVDRLCLGIP PGECFGLLGV NGAGKTSTFR MVTGDTLPSS GEAVLAGHNV AQERSAAHRS MGYCPQSDAI FDLLTGREHL ELFARLRGVP EAQVAQTALS GLVRLGLPSY ADRPAGTYSG GNKRKLATAL ALVGDPAVVF LDEPTTGMDP SARRFLWNSL LSVVREGRSV VLTSHSMEEC EALCTRLAIM VNGRFRCLGS SQHLKGRFGA GHTLTLRVPP DQPEPAIAFI RITFPGAELR EVHGSRLRFQ LPPGGRCTLT RVFRELAAQG RAHGVEDFSV SQTTLEEVFL YFSKDQGEEE ESSRQEAEEE EVSKPGRQHP KRVSRFLEDP SSVETMI
Database document:
This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.