Details for: Abcg5

Gene ID: 27409

Symbol: Abcg5

Ensembl ID: ENSMUSG00000040505

Description: ATP binding cassette subfamily G member 5

Associated with

Other Information

Genular Protein ID: 599798829

Symbol: ABCG5_MOUSE

Name: N/A

UniProtKB Accession Codes:

Database IDs:

Citations:

PubMed ID: 11138003

Title: Identification of a gene, ABCG5, important in the regulation of dietary cholesterol absorption.

PubMed ID: 11138003

DOI: 10.1038/83799

PubMed ID: 11907139

Title: Molecular cloning, genomic organization, genetic variations, and characterization of murine sterolin genes Abcg5 and Abcg8.

PubMed ID: 11907139

PubMed ID: 12949731

Title: FXR and ABCG5/ABCG8 as determinants of cholesterol gallstone formation from quantitative trait locus mapping in mice.

PubMed ID: 12949731

DOI: 10.1016/s0016-5085(03)01053-9

PubMed ID: 16141072

Title: The transcriptional landscape of the mammalian genome.

PubMed ID: 16141072

DOI: 10.1126/science.1112014

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 11099417

Title: Accumulation of dietary cholesterol in sitosterolemia caused by mutations in adjacent ABC transporters.

PubMed ID: 11099417

DOI: 10.1126/science.290.5497.1771

PubMed ID: 12208867

Title: Coexpression of ATP-binding cassette proteins ABCG5 and ABCG8 permits their transport to the apical surface.

PubMed ID: 12208867

DOI: 10.1172/jci16000

PubMed ID: 12444248

Title: Disruption of Abcg5 and Abcg8 in mice reveals their crucial role in biliary cholesterol secretion.

PubMed ID: 12444248

DOI: 10.1073/pnas.252582399

PubMed ID: 14504269

Title: ABCG5 and ABCG8 are obligate heterodimers for protein trafficking and biliary cholesterol excretion.

PubMed ID: 14504269

DOI: 10.1074/jbc.m310223200

PubMed ID: 12777468

Title: Endotoxin down-regulates ABCG5 and ABCG8 in mouse liver and ABCA1 and ABCG1 in J774 murine macrophages: differential role of LXR.

PubMed ID: 12777468

DOI: 10.1194/jlr.m300100-jlr200

PubMed ID: 15040800

Title: A mouse model of sitosterolemia: absence of Abcg8/sterolin-2 results in failure to secrete biliary cholesterol.

PubMed ID: 15040800

DOI: 10.1186/1741-7015-2-5

PubMed ID: 15054092

Title: Missense mutations in ABCG5 and ABCG8 disrupt heterodimerization and trafficking.

PubMed ID: 15054092

DOI: 10.1074/jbc.m402634200

PubMed ID: 14657202

Title: Selective sterol accumulation in ABCG5/ABCG8-deficient mice.

PubMed ID: 14657202

DOI: 10.1194/jlr.m300377-jlr200

PubMed ID: 16352607

Title: Functional asymmetry of nucleotide-binding domains in ABCG5 and ABCG8.

PubMed ID: 16352607

DOI: 10.1074/jbc.m512277200

PubMed ID: 16867993

Title: Sterol transfer by ABCG5 and ABCG8: in vitro assay and reconstitution.

PubMed ID: 16867993

DOI: 10.1074/jbc.m605603200

PubMed ID: 18402465

Title: Purification and reconstitution of sterol transfer by native mouse ABCG5 and ABCG8.

PubMed ID: 18402465

DOI: 10.1021/bi800292v

PubMed ID: 19846887

Title: The mouse mutation 'thrombocytopenia and cardiomyopathy' (trac) disrupts Abcg5: a spontaneous single gene model for human hereditary phytosterolemia/sitosterolemia.

PubMed ID: 19846887

DOI: 10.1182/blood-2009-05-219808

PubMed ID: 21183079

Title: A tissue-specific atlas of mouse protein phosphorylation and expression.

PubMed ID: 21183079

DOI: 10.1016/j.cell.2010.12.001

PubMed ID: 25378657

Title: Relative roles of ABCG5/ABCG8 in liver and intestine.

PubMed ID: 25378657

DOI: 10.1194/jlr.m054544

Sequence Information:

  • Length: 652
  • Mass: 73244
  • Checksum: 80CE37ADCC19771E
  • Sequence:
  • MGELPFLSPE GARGPHINRG SLSSLEQGSV TGTEARHSLG VLHVSYSVSN RVGPWWNIKS 
    CQQKWDRQIL KDVSLYIESG QIMCILGSSG SGKTTLLDAI SGRLRRTGTL EGEVFVNGCE 
    LRRDQFQDCF SYVLQSDVFL SSLTVRETLR YTAMLALCRS SADFYNKKVE AVMTELSLSH 
    VADQMIGSYN FGGISSGERR RVSIAAQLLQ DPKVMMLDEP TTGLDCMTAN QIVLLLAELA 
    RRDRIVIVTI HQPRSELFQH FDKIAILTYG ELVFCGTPEE MLGFFNNCGY PCPEHSNPFD 
    FYMDLTSVDT QSREREIETY KRVQMLECAF KESDIYHKIL ENIERARYLK TLPTVPFKTK 
    DPPGMFGKLG VLLRRVTRNL MRNKQAVIMR LVQNLIMGLF LIFYLLRVQN NTLKGAVQDR 
    VGLLYQLVGA TPYTGMLNAV NLFPMLRAVS DQESQDGLYH KWQMLLAYVL HVLPFSVIAT 
    VIFSSVCYWT LGLYPEVARF GYFSAALLAP HLIGEFLTLV LLGIVQNPNI VNSIVALLSI 
    SGLLIGSGFI RNIQEMPIPL KILGYFTFQK YCCEILVVNE FYGLNFTCGG SNTSMLNHPM 
    CAITQGVQFI EKTCPGATSR FTANFLILYG FIPALVILGI VIFKVRDYLI SR

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.