Naglu | ENSMUSG00000001751 | NCBI 27419

Details for: Naglu

Gene ID: 27419

Symbol: Naglu

Ensembl ID: ENSMUSG00000001751

Description: alpha-N-acetylglucosaminidase (Sanfilippo disease IIIB)

Associated with

Glycosaminoglycan metabolism
(R-MMU-1630316)
Heparan sulfate/heparin (hs-gag) metabolism
(R-MMU-1638091)
Hs-gag degradation
(R-MMU-2024096)
Metabolism
(R-MMU-1430728)
Metabolism of carbohydrates
(R-MMU-71387)
Adult behavior
(GO:0030534)
Alpha-n-acetylglucosaminidase activity
(GO:0004561)
Amyloid precursor protein metabolic process
(GO:0042982)
Aorta development
(GO:0035904)
Aorta morphogenesis
(GO:0035909)
Astrocyte activation
(GO:0048143)
Astrocyte differentiation
(GO:0048708)
Autophagy
(GO:0006914)
Cardiac muscle cell development
(GO:0055013)
Cell surface receptor signaling pathway via stat
(GO:0097696)
Cellular lipid catabolic process
(GO:0044242)
Cellular response to organic cyclic compound
(GO:0071407)
Cellular response to oxidative stress
(GO:0034599)
Cerebellar purkinje cell layer development
(GO:0021680)
Collagen metabolic process
(GO:0032963)
Cone retinal bipolar cell differentiation
(GO:1904390)
Cytoplasm organization
(GO:0007028)
Determination of adult lifespan
(GO:0008340)
Endothelium development
(GO:0003158)
Exploration behavior
(GO:0035640)
Extracellular exosome
(GO:0070062)
Ganglioside metabolic process
(GO:0001573)
Gene expression
(GO:0010467)
Glycoprotein metabolic process
(GO:0009100)
Glycosaminoglycan metabolic process
(GO:0030203)
Golgi organization
(GO:0007030)
Hair follicle morphogenesis
(GO:0031069)
Heart development
(GO:0007507)
Heart valve development
(GO:0003170)
Heparan sulfate proteoglycan catabolic process
(GO:0030200)
Heparan sulfate proteoglycan metabolic process
(GO:0030201)
Heparin metabolic process
(GO:0030202)
Hormone metabolic process
(GO:0042445)
Inflammatory response
(GO:0006954)
Inner ear receptor cell development
(GO:0060119)
Left ventricular cardiac muscle tissue morphogenesis
(GO:0003220)
Limb development
(GO:0060173)
Liver development
(GO:0001889)
Locomotor rhythm
(GO:0045475)
Locomotory behavior
(GO:0007626)
Lysosomal lumen
(GO:0043202)
Lysosome organization
(GO:0007040)
Maintenance of blood-brain barrier
(GO:0035633)
Microglia differentiation
(GO:0014004)
Microglial cell activation
(GO:0001774)
Middle ear morphogenesis
(GO:0042474)
Mitral valve morphogenesis
(GO:0003183)
Motor behavior
(GO:0061744)
Multicellular organismal-level iron ion homeostasis
(GO:0060586)
Nerve development
(GO:0021675)
Neurogenesis
(GO:0022008)
Neuroinflammatory response
(GO:0150076)
Proteasome-mediated ubiquitin-dependent protein catabolic process
(GO:0043161)
Protein metabolic process
(GO:0019538)
Protein oxidation
(GO:0018158)
Protein processing
(GO:0016485)
Proteoglycan metabolic process
(GO:0006029)
Response to disaccharide
(GO:0034285)
Response to lipopolysaccharide
(GO:0032496)
Response to wounding
(GO:0009611)
Retina development in camera-type eye
(GO:0060041)
Retinal rod cell development
(GO:0046548)
Rod bipolar cell differentiation
(GO:1904389)
Sequestering of iron ion
(GO:0097577)
Superoxide metabolic process
(GO:0006801)
Toll-like receptor 4 signaling pathway
(GO:0034142)
Vacuole
(GO:0005773)
Vacuole organization
(GO:0007033)
Vasculature development
(GO:0001944)
Vesicle tethering
(GO:0099022)

Other Information

Proteins

O88325_MOUSE

Genular Protein ID: 2486437741

Symbol: O88325_MOUSE

Name: N/A

UniProtKB Accession Codes:

O88325

Database IDs:

Citations:

PubMed ID: 10349636

Title: High-efficiency full-length cDNA cloning.

PubMed ID: 10349636

DOI: 10.1016/S0076-6879(99)03004-9

PubMed ID: 10588735

Title: Mouse model of Sanfilippo syndrome type B produced by targeted disruption of the gene encoding alpha-N-acetylglucosaminidase.

PubMed ID: 10588735

DOI: 10.1073/pnas.96.25.14505

PubMed ID: 11042159

Title: Normalization and subtraction of cap-trapper-selected cDNAs to prepare full-length cDNA libraries for rapid discovery of new genes.

PubMed ID: 11042159

DOI: 10.1101/gr.145100

PubMed ID: 11076861

Title: RIKEN integrated sequence analysis (RISA) system--384-format sequencing pipeline with 384 multicapillary sequencer.

PubMed ID: 11076861

DOI: 10.1101/gr.152600

PubMed ID: 11217851

Title: Functional annotation of a full-length mouse cDNA collection.

PubMed ID: 11217851

DOI: 10.1038/35055500

PubMed ID: 12466851

Title: Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs.

PubMed ID: 12466851

DOI: 10.1038/nature01266

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 16141073

Title: Antisense Transcription in the Mammalian Transcriptome.

PubMed ID: 16141073

DOI: 10.1126/science.1112009

PubMed ID: 19468303

Title: Lineage-specific biology revealed by a finished genome assembly of the mouse.

PubMed ID: 19468303

DOI: 10.1371/journal.pbio.1000112

PubMed ID: 21183079

Title: A tissue-specific atlas of mouse protein phosphorylation and expression.

PubMed ID: 21183079

DOI: 10.1016/j.cell.2010.12.001

PubMed ID: 21750661

Title: Modernizing reference genome assemblies.

PubMed ID: 21750661

Sequence Information:

Length: 739
Mass: 82596
Checksum: 01C71966557CDE27
Sequence:

MEAAGLAVIL GFLLLAGGSV GDEAREAKAV RELVVRLLGP GPAANFLVSV ERALADESGL 
DTYSLSGGGG VPVLVRGSTG VAAAAGLHRY LRDFCGCQVA WSSAQLHLPW PLPAVPDGLT 
ETTPNRYRYY QNVCTHSYSF VWWDWARWEQ EIDWMALNGI NLALAWNGQE AIWQRVYLAL 
GLTQSEIDTY FTGPAFLAWG RMGNLHTWDG PLPRSWHLSQ VYLQHRILDR MRSFGMIPVL 
PAFAGHVPKA ITRVFPQVNV IKLGSWGHFN CSYSCSFLLA PGDPMFPLIG NLFLRELTKE 
FGTDHIYGAD TFNEMQPPFS DPSYLAATTA AVYEAMVTVD PDAVWLLQGW LFQHQPQFWG 
PSQIRAVLEA VPRGRLLVLD LFAESHPVYM HTASFHGQPF IWCMLHNFGG NHGLFGALED 
VNRGPQAARL FPNSTMVGTG IAPEGIGQNE VVYALMAELG WRKDPVPDLM AWVSSFAIRR 
YGVSQPDAVA AWKLLLRSVY NCSGEACSGH NRSPLVKRPS LQMSTAVWYN RSDVFEAWRL 
LLTAAPNLTT SPAFRYDLLD VTRQAVQELV SLCYEEARTA YLKQELDLLL RAGGLLVYKL 
LPTLDELLAS SSHFLLGTWL DQARKAAVSE AEAQFYEQNS RYQITLWGPE GNILDYANKQ 
LAGLVADYYQ PRWCLFLGTL AHSLARGVPF QQHEFEKNVF PLEQAFVYNK KRYPSQPRGD 
TVDLSKKIFL KYHPQPDSL

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: Naglu

Associated with

Other Information

High-efficiency full-length cDNA cloning. PubMed ID: 10349636

Mouse model of Sanfilippo syndrome type B produced by targeted disruption of the gene encoding alpha-N-acetylglucosaminidase. PubMed ID: 10588735

Normalization and subtraction of cap-trapper-selected cDNAs to prepare full-length cDNA libraries for rapid discovery of new genes. PubMed ID: 11042159

RIKEN integrated sequence analysis (RISA) system--384-format sequencing pipeline with 384 multicapillary sequencer. PubMed ID: 11076861

Functional annotation of a full-length mouse cDNA collection. PubMed ID: 11217851

Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. PubMed ID: 12466851

The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). PubMed ID: 15489334

Antisense Transcription in the Mammalian Transcriptome. PubMed ID: 16141073

Lineage-specific biology revealed by a finished genome assembly of the mouse. PubMed ID: 19468303

A tissue-specific atlas of mouse protein phosphorylation and expression. PubMed ID: 21183079

Modernizing reference genome assemblies. PubMed ID: 21750661