Eif3b | ENSMUSG00000056076 | NCBI 27979

Details for: Eif3b

Gene ID: 27979

Symbol: Eif3b

Ensembl ID: ENSMUSG00000056076

Description: eukaryotic translation initiation factor 3, subunit B

Associated with

Activation of the mrna upon binding of the cap-binding complex and eifs, and subsequent binding to 43s
(R-MMU-72662)
Cap-dependent translation initiation
(R-MMU-72737)
Eukaryotic translation initiation
(R-MMU-72613)
Formation of a pool of free 40s subunits
(R-MMU-72689)
Formation of the ternary complex, and subsequently, the 43s complex
(R-MMU-72695)
Gtp hydrolysis and joining of the 60s ribosomal subunit
(R-MMU-72706)
L13a-mediated translational silencing of ceruloplasmin expression
(R-MMU-156827)
Metabolism of proteins
(R-MMU-392499)
Ribosomal scanning and start codon recognition
(R-MMU-72702)
Translation initiation complex formation
(R-MMU-72649)
Cytoplasm
(GO:0005737)
Cytoplasmic stress granule
(GO:0010494)
Eukaryotic translation initiation factor 3 complex
(GO:0005852)
Eukaryotic translation initiation factor 3 complex, eif3m
(GO:0071541)
Ires-dependent viral translational initiation
(GO:0075522)
Nucleic acid binding
(GO:0003676)
Protein binding
(GO:0005515)
Regulation of translational initiation
(GO:0006446)
Rna binding
(GO:0003723)
Synapse
(GO:0045202)
Translation
(GO:0006412)
Translational initiation
(GO:0006413)
Translation initiation factor activity
(GO:0003743)
Translation initiation factor binding
(GO:0031369)
Viral translational termination-reinitiation
(GO:0075525)

Other Information

Proteins

eIF3 p116

Genular Protein ID: 3733485276

Symbol: EIF3B_MOUSE

Name: eIF3 p116

UniProtKB Accession Codes:

Q8JZQ9 Q922K2

Database IDs:

Citations:

PubMed ID: 12038979

Title: Embryonic lethality of mutant mice deficient in the p116 gene.

PubMed ID: 12038979

DOI: 10.1093/oxfordjournals.jbchem.a003172

PubMed ID: 16141072

Title: The transcriptional landscape of the mammalian genome.

PubMed ID: 16141072

DOI: 10.1126/science.1112014

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 15345747

Title: Phosphoproteomic analysis of the developing mouse brain.

PubMed ID: 15345747

DOI: 10.1074/mcp.m400085-mcp200

PubMed ID: 16541103

Title: mTOR-dependent stimulation of the association of eIF4G and eIF3 by insulin.

PubMed ID: 16541103

DOI: 10.1038/sj.emboj.7601047

PubMed ID: 16452087

Title: Comprehensive identification of phosphorylation sites in postsynaptic density preparations.

PubMed ID: 16452087

DOI: 10.1074/mcp.t500041-mcp200

PubMed ID: 17581632

Title: Reconstitution reveals the functional core of mammalian eIF3.

PubMed ID: 17581632

DOI: 10.1038/sj.emboj.7601765

PubMed ID: 17622165

Title: A differential phosphoproteomic analysis of retinoic acid-treated P19 cells.

PubMed ID: 17622165

DOI: 10.1021/pr070122r

PubMed ID: 17242355

Title: Large-scale phosphorylation analysis of mouse liver.

PubMed ID: 17242355

DOI: 10.1073/pnas.0609836104

PubMed ID: 18630941

Title: Specific phosphopeptide enrichment with immobilized titanium ion affinity chromatography adsorbent for phosphoproteome analysis.

PubMed ID: 18630941

DOI: 10.1021/pr800223m

PubMed ID: 19144319

Title: The phagosomal proteome in interferon-gamma-activated macrophages.

PubMed ID: 19144319

DOI: 10.1016/j.immuni.2008.11.006

PubMed ID: 19131326

Title: Large scale localization of protein phosphorylation by use of electron capture dissociation mass spectrometry.

PubMed ID: 19131326

DOI: 10.1074/mcp.m800451-mcp200

PubMed ID: 21183079

Title: A tissue-specific atlas of mouse protein phosphorylation and expression.

PubMed ID: 21183079

DOI: 10.1016/j.cell.2010.12.001

Sequence Information:

Length: 803
Mass: 91370
Checksum: D770AC70BFE9832F
Sequence:

MQDAENVAVP EAAEERAEPA RQQPASESPP TDEAAGSGGS EVGQTEDAEE DAEAGPEPEV 
RAKPAAQSEE ETATSPAASP TPQSAERSPS QEPSAPGKAE AVGEQARGHP SAGAEEEGGS 
DGSAAEAEPR ALENGEADEP SFSDPEDFVD DVSEEELLGD VLKDRPQEAD GIDSVIVVDN 
VPQVGPDRLE KLKNVIHKIF SKFGKIINDY YPEEDGKTKG YIFLEYASPA HAVDAVKNAD 
GYKLDKQHTF RVNLFTDFDK YMTISDEWDI PEKQPFKDLG NLRYWLEEAE CRDQYSVIFE 
SGDRTSIFWN DVKDPVSIEE RARWTETYVR WSPKGTYLAT FHQRGIALWG GDKFKQIQRF 
SHQGVQLIDF SPCERYLVTF SPLMDTQDDP QAIIIWDILT GHKKRGFHCE SSAHWPIFKW 
SHDGKFFARM TLDTLSIYET PSMGLLDKKS LKISGIKDFS WSPGGNIIAF WVPEDKDIPA 
RVTLMQLPTR QEIRVRNLFN VVDCKLHWQK NGDYLCVKVD RTPKGTQGVV TNFEIFRMRE 
KQVPVDVVEM KETIIAFAWE PNGSKFAVLH GEAPRISVSF YHVKSNGKIE LIKMFDKQQA 
NTIFWSPQGQ FVVLAGLRSM NGALAFVDTS DCTVMNIAEH YMASDVEWDP TGRYVVTSVS 
WWSHKVDNAY WLWTFQGRLL QKNNKDRFCQ LLWRPRPPTL LSQDQIKQIK KDLKKYSKIF 
EQKDRLSQSK ASKELVERRR TMMEDFRQYR KMAQELYMKQ KNERLELRGG VDTDELDSNV 
DDWEEETIEF FVTEEVIPLG SQE

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: Eif3b

Associated with

Other Information

Embryonic lethality of mutant mice deficient in the p116 gene. PubMed ID: 12038979

The transcriptional landscape of the mammalian genome. PubMed ID: 16141072

The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). PubMed ID: 15489334

Phosphoproteomic analysis of the developing mouse brain. PubMed ID: 15345747

mTOR-dependent stimulation of the association of eIF4G and eIF3 by insulin. PubMed ID: 16541103

Comprehensive identification of phosphorylation sites in postsynaptic density preparations. PubMed ID: 16452087

Reconstitution reveals the functional core of mammalian eIF3. PubMed ID: 17581632

A differential phosphoproteomic analysis of retinoic acid-treated P19 cells. PubMed ID: 17622165

Large-scale phosphorylation analysis of mouse liver. PubMed ID: 17242355

Specific phosphopeptide enrichment with immobilized titanium ion affinity chromatography adsorbent for phosphoproteome analysis. PubMed ID: 18630941

The phagosomal proteome in interferon-gamma-activated macrophages. PubMed ID: 19144319

Large scale localization of protein phosphorylation by use of electron capture dissociation mass spectrometry. PubMed ID: 19131326

A tissue-specific atlas of mouse protein phosphorylation and expression. PubMed ID: 21183079