Details for: ABO

Gene ID: 28

Symbol: ABO

Ensembl ID: ENSG00000175164

Description: ABO, alpha 1-3-N-acetylgalactosaminyltransferase and alpha 1-3-galactosyltransferase

Associated with

Other Information

Genular Protein ID: 1625791966

Symbol: BGAT_HUMAN

Name: Histo-blood group ABO system transferase

UniProtKB Accession Codes:

Database IDs:

Citations:

PubMed ID: 2104828

Title: Cloning and characterization of DNA complementary to human UDP-GalNAc: Fuc alpha 1-->2Gal alpha 1-->3GalNAc transferase (histo-blood group A transferase) mRNA.

PubMed ID: 2104828

DOI: 10.1016/s0021-9258(19)40170-1

PubMed ID: 2333095

Title: Molecular genetic basis of the histo-blood group ABO system.

PubMed ID: 2333095

DOI: 10.1038/345229a0

PubMed ID: 7598760

Title: Genomic cloning of the human histo-blood group ABO locus.

PubMed ID: 7598760

DOI: 10.1006/bbrc.1995.1044

PubMed ID: 7779106

Title:

PubMed ID: 7779106

DOI: 10.1006/bbrc.1995.1817

PubMed ID: 16533287

Title: A weak blood group A phenotype caused by a translation-initiator mutation in the ABO gene.

PubMed ID: 16533287

DOI: 10.1111/j.1537-2995.2006.00740.x

PubMed ID: 17764507

Title: Weak blood group B phenotypes may be caused by variations in the CCAAT-binding factor/NF-Y enhancer region of the ABO gene.

PubMed ID: 17764507

DOI: 10.1111/j.1537-2995.2007.01475.x

PubMed ID: 18513251

Title: Aberrant intracellular trafficking of a variant B glycosyltransferase.

PubMed ID: 18513251

DOI: 10.1111/j.1537-2995.2008.01782.x

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 12829588

Title: The nature of diversity and diversification at the ABO locus.

PubMed ID: 12829588

DOI: 10.1182/blood-2003-03-0955

PubMed ID: 8839869

Title: Molecular genetic analysis of variant phenotypes of the ABO blood group system.

PubMed ID: 8839869

PubMed ID: 9800297

Title: Heterogeneity of the blood group Ax allele: genetic recombination of common alleles can result in the Ax phenotype.

PubMed ID: 9800297

DOI: 10.1046/j.1365-3148.1998.00161.x

PubMed ID: 15104652

Title: Evolution of the O alleles of the human ABO blood group gene.

PubMed ID: 15104652

DOI: 10.1111/j.1537-2995.2004.03346.x

PubMed ID: 1449469

Title: Animal histo-blood group ABO genes.

PubMed ID: 1449469

DOI: 10.1016/0006-291x(92)91538-2

PubMed ID: 2121736

Title: Sugar-nucleotide donor specificity of histo-blood group A and B transferases is based on amino acid substitutions.

PubMed ID: 2121736

DOI: 10.1016/s0021-9258(17)30652-x

PubMed ID: 10462501

Title: The molecular basis for the B(A) allele: an amino acid alteration in the human histoblood group B alpha-(1,3)-galactosyltransferase increases its intrinsic alpha-(1,3)-N-acetylgalactosaminyltransferase activity.

PubMed ID: 10462501

DOI: 10.1006/bbrc.1999.1246

PubMed ID: 12198488

Title: The structural basis for specificity in human ABO(H) blood group biosynthesis.

PubMed ID: 12198488

DOI: 10.1038/nsb832

PubMed ID: 12529355

Title: A single point mutation reverses the donor specificity of human blood group B-synthesizing galactosyltransferase.

PubMed ID: 12529355

DOI: 10.1074/jbc.m212002200

PubMed ID: 12972418

Title: The influence of an intramolecular hydrogen bond in differential recognition of inhibitory acceptor analogs by human ABO(H) blood group A and B glycosyltransferases.

PubMed ID: 12972418

DOI: 10.1074/jbc.m308770200

PubMed ID: 15475562

Title: Structural basis for the inactivity of human blood group O2 glycosyltransferase.

PubMed ID: 15475562

DOI: 10.1074/jbc.m410245200

PubMed ID: 16326711

Title: Differential recognition of the type I and II H antigen acceptors by the human ABO(H) blood group A and B glycosyltransferases.

PubMed ID: 16326711

DOI: 10.1074/jbc.m507620200

PubMed ID: 17259183

Title: Structural effects of naturally occurring human blood group B galactosyltransferase mutations adjacent to the DXD motif.

PubMed ID: 17259183

DOI: 10.1074/jbc.m610998200

Sequence Information:

  • Length: 354
  • Mass: 40934
  • Checksum: A03DA16E630C1608
  • Sequence:
  • MAEVLRTLAG KPKCHALRPM ILFLIMLVLV LFGYGVLSPR SLMPGSLERG FCMAVREPDH 
    LQRVSLPRMV YPQPKVLTPC RKDVLVVTPW LAPIVWEGTF NIDILNEQFR LQNTTIGLTV 
    FAIKKYVAFL KLFLETAEKH FMVGHRVHYY VFTDQPAAVP RVTLGTGRQL SVLEVRAYKR 
    WQDVSMRRME MISDFCERRF LSEVDYLVCV DVDMEFRDHV GVEILTPLFG TLHPGFYGSS 
    REAFTYERRP QSQAYIPKDE GDFYYLGGFF GGSVQEVQRL TRACHQAMMV DQANGIEAVW 
    HDESHLNKYL LRHKPTKVLS PEYLWDQQLL GWPAVLRKLR FTAVPKNHQA VRNP

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.