Details for: Nsun2

Gene ID: 28114

Symbol: Nsun2

Ensembl ID: ENSMUSG00000021595

Description: NOL1/NOP2/Sun domain family member 2

Associated with

Other Information

Genular Protein ID: 3730967121

Symbol: NSUN2_MOUSE

Name: N/A

UniProtKB Accession Codes:

Database IDs:

Citations:

PubMed ID: 16713953

Title: The RNA methyltransferase Misu (NSun2) mediates Myc-induced proliferation and is upregulated in tumors.

PubMed ID: 16713953

DOI: 10.1016/j.cub.2006.04.027

PubMed ID: 16141072

Title: The transcriptional landscape of the mammalian genome.

PubMed ID: 16141072

DOI: 10.1126/science.1112014

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 15345747

Title: Phosphoproteomic analysis of the developing mouse brain.

PubMed ID: 15345747

DOI: 10.1074/mcp.m400085-mcp200

PubMed ID: 17242355

Title: Large-scale phosphorylation analysis of mouse liver.

PubMed ID: 17242355

DOI: 10.1073/pnas.0609836104

PubMed ID: 19144319

Title: The phagosomal proteome in interferon-gamma-activated macrophages.

PubMed ID: 19144319

DOI: 10.1016/j.immuni.2008.11.006

PubMed ID: 19596847

Title: The nucleolar RNA methyltransferase Misu (NSun2) is required for mitotic spindle stability.

PubMed ID: 19596847

DOI: 10.1083/jcb.200810180

PubMed ID: 21183079

Title: A tissue-specific atlas of mouse protein phosphorylation and expression.

PubMed ID: 21183079

DOI: 10.1016/j.cell.2010.12.001

PubMed ID: 22144916

Title: The RNA-methyltransferase Misu (NSun2) poises epidermal stem cells to differentiate.

PubMed ID: 22144916

DOI: 10.1371/journal.pgen.1002403

PubMed ID: 22885326

Title: RNA cytosine methylation by Dnmt2 and NSun2 promotes tRNA stability and protein synthesis.

PubMed ID: 22885326

DOI: 10.1038/nsmb.2357

PubMed ID: 23871666

Title: NSun2-mediated cytosine-5 methylation of vault noncoding RNA determines its processing into regulatory small RNAs.

PubMed ID: 23871666

DOI: 10.1016/j.celrep.2013.06.029

PubMed ID: 23401851

Title: The mouse cytosine-5 RNA methyltransferase NSun2 is a component of the chromatoid body and required for testis differentiation.

PubMed ID: 23401851

DOI: 10.1128/mcb.01523-12

PubMed ID: 23806337

Title: SIRT5-mediated lysine desuccinylation impacts diverse metabolic pathways.

PubMed ID: 23806337

DOI: 10.1016/j.molcel.2013.06.001

PubMed ID: 28341602

Title: Cytosolic YB-1 and NSUN2 are the only proteins recognizing specific motifs present in mRNAs enriched in exosomes.

PubMed ID: 28341602

DOI: 10.1016/j.bbapap.2017.03.010

PubMed ID: 31276587

Title: NSUN2 introduces 5-methylcytosines in mammalian mitochondrial tRNAs.

PubMed ID: 31276587

DOI: 10.1093/nar/gkz559

PubMed ID: 31287866

Title: Mammalian NSUN2 introduces 5-methylcytidines into mitochondrial tRNAs.

PubMed ID: 31287866

DOI: 10.1093/nar/gkz575

PubMed ID: 31199786

Title: Cytosine-5 RNA methylation links protein synthesis to cell metabolism.

PubMed ID: 31199786

DOI: 10.1371/journal.pbio.3000297

Sequence Information:

  • Length: 757
  • Mass: 85452
  • Checksum: 73B06947DEC50298
  • Sequence:
  • MGRRARGRRF QQPPQPEGEE DASDGGRKRG QAGWEGGYPE IVKENKLFEH YYQELKIVPE 
    GEWDQFMESL REPLPATLRI TGYKSHAKEI LHCLKNKYFK ELEDLEVDGQ KVEVPQPLSW 
    YPEELAWHTN LSRKILRKSP LLAKFHQFLV SETESGNISR QEAVSMIPPL LLNVEPHHKI 
    LDMCAAPGSK TTQLIEMLHA DMSVPFPEGF VIANDVDNKR CYLLVHQAKR LSSPCIMVVN 
    HDASSIPRLT VDVDGRKEIL FYDRILCDVP CSGDGTMRKN IDVWKKWTTL NSLQLHGLQL 
    RIATRGAEQL AEGGRMVYST CSLNPVEDEA VIAALLEKSE GALELADVSA ELPGLKWMPG 
    VSQWKVMTRD GQWFADWHEV PQGRHTQIRP TMFPPTDLEK LQAMHLERCL RILPHHQNTG 
    GFFVAVLVKK APMPWNKRQP KVQNKSAEAR EPRVSSHVAA TEGNPSDQSE LESQMITGAG 
    DSETAHNTEN TESNEKKDGV CGPPPSKKMK LFGFKEDPFV FIPEDDPLFP PIEKFYALDP 
    SFPRMNLLTR TTEGKKRQLY MVSKELRNVL LNNSEKMKVI NTGIKVWCRN NSGEEFDCAF 
    RLAQEGIYTL YPFINSRIIT VSMEDVKTLL TQENPFFRKL SSEAYSQVKD LAKGSVVLKY 
    EPDSANPDTL QCPIVLCGWR GKASIRTFVP KNERLHYLRM MGLEVLGEKK KEGVILTNEN 
    AASPEQPGDE DAKQTAQDPC VPDSVPGCDA AAAEPSR

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.