Tomm70a | ENSMUSG00000022752 | NCBI 28185

Details for: Tomm70a

Gene ID: 28185

Symbol: Tomm70a

Ensembl ID: ENSMUSG00000022752

Description: translocase of outer mitochondrial membrane 70A

Associated with

Autophagy
(R-MMU-9612973)
Ddx58/ifih1-mediated induction of interferon-alpha/beta
(R-MMU-168928)
Deubiquitination
(R-MMU-5688426)
Immune system
(R-MMU-168256)
Innate immune system
(R-MMU-168249)
Macroautophagy
(R-MMU-1632852)
Metabolism of proteins
(R-MMU-392499)
Mitophagy
(R-MMU-5205647)
Pink1-prkn mediated mitophagy
(R-MMU-5205685)
Post-translational protein modification
(R-MMU-597592)
Selective autophagy
(R-MMU-9663891)
Ub-specific processing proteases
(R-MMU-5689880)
Activation of innate immune response
(GO:0002218)
Cellular response to virus
(GO:0098586)
Membrane
(GO:0016020)
Mitochondrial membrane
(GO:0031966)
Mitochondrial outer membrane
(GO:0005741)
Mitochondrion
(GO:0005739)
Mitochondrion targeting sequence binding
(GO:0030943)
Molecular adaptor activity
(GO:0060090)
Negative regulation of cell growth involved in cardiac muscle cell development
(GO:0061052)
Positive regulation of defense response to virus by host
(GO:0002230)
Positive regulation of interferon-beta production
(GO:0032728)
Positive regulation of protein targeting to mitochondrion
(GO:1903955)
Protein binding
(GO:0005515)
Protein import into mitochondrial matrix
(GO:0030150)
Protein insertion into mitochondrial inner membrane
(GO:0045039)
Protein targeting to mitochondrion
(GO:0006626)
Protein transmembrane transporter activity
(GO:0008320)
Regulation of apoptotic process
(GO:0042981)

Other Information

Proteins

Mitochondrial precursor proteins import receptor

Genular Protein ID: 206453337

Symbol: TOM70_MOUSE

Name: Mitochondrial precursor proteins import receptor

UniProtKB Accession Codes:

Q9CZW5 Q8BNI6

Database IDs:

Citations:

PubMed ID: 16141072

Title: The transcriptional landscape of the mammalian genome.

PubMed ID: 16141072

DOI: 10.1126/science.1112014

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 16476741

Title: Stomach-specific calpain, nCL-2, localizes in mucus cells and proteolyzes the beta-subunit of coatomer complex, beta-COP.

PubMed ID: 16476741

DOI: 10.1074/jbc.m509244200

PubMed ID: 17208939

Title: Mitochondrial phosphoproteome revealed by an improved IMAC method and MS/MS/MS.

PubMed ID: 17208939

DOI: 10.1074/mcp.m600218-mcp200

PubMed ID: 18630941

Title: Specific phosphopeptide enrichment with immobilized titanium ion affinity chromatography adsorbent for phosphoproteome analysis.

PubMed ID: 18630941

DOI: 10.1021/pr800223m

PubMed ID: 19144319

Title: The phagosomal proteome in interferon-gamma-activated macrophages.

PubMed ID: 19144319

DOI: 10.1016/j.immuni.2008.11.006

PubMed ID: 19131326

Title: Large scale localization of protein phosphorylation by use of electron capture dissociation mass spectrometry.

PubMed ID: 19131326

DOI: 10.1074/mcp.m800451-mcp200

PubMed ID: 21183079

Title: A tissue-specific atlas of mouse protein phosphorylation and expression.

PubMed ID: 21183079

DOI: 10.1016/j.cell.2010.12.001

PubMed ID: 20628368

Title: Tom70 mediates activation of interferon regulatory factor 3 on mitochondria.

PubMed ID: 20628368

DOI: 10.1038/cr.2010.103

Sequence Information:

Length: 611
Mass: 67590
Checksum: 5103C658D8BF9C53
Sequence:

MAASKPIEAA MAAAAAPGSG NGVGGGGGTA GPGSGAGTLP RWHVALAIGA PLLLGAGAMY 
LWSRRRRRRE AGGRGDASGL KRNSERKTPE GRASPALGSG HHDGSGDSLE MSSLDRAQAA 
KNKGNKYFKA GKYEQAIQCY TEAISLCPTE KNVDLSTFYQ NRAAAFEQLQ KWKEVAQDCT 
KAVELNPKYV KALFRRAKAH EKLDNKKECL EDVTAVCILE GFQNEQSMLL ADKVLKLLGK 
ENAKEKYKNR EPLMPSPQFI KSYFSSFTDD IISQPMLKGE KSDEDKDKEG EALEVKENSG 
YLKAKQYMEE ENYDKIISEC SKEIDAQGKY MAEALLLRAT FYLLIGSANA AKPDLDKVIS 
LKEANVKLRA NALIKRGTMC MQQQQPMLST QDFNMAAEID PMNSDVYHHR GQLKILLDLV 
EEAVADFDAC IRLRPKFALA QAQKCFALYR QAYTANNSSQ VQAAMKGFEE IIKKFPRCAE 
GYALYAQALT DQQQFGKADE MYDKCIDLEP DNATTYVHKG LLQLQWKQDL DKGLELISKA 
IEIDNKCDFA YETMGTIEVQ RGNMEKAIDM FNKAINLAKS EMEMAHLYSL CDAAHAQTEV 
AKKYGLKPPT L

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: Tomm70a

Associated with

Other Information

The transcriptional landscape of the mammalian genome. PubMed ID: 16141072

The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). PubMed ID: 15489334

Stomach-specific calpain, nCL-2, localizes in mucus cells and proteolyzes the beta-subunit of coatomer complex, beta-COP. PubMed ID: 16476741

Mitochondrial phosphoproteome revealed by an improved IMAC method and MS/MS/MS. PubMed ID: 17208939

Specific phosphopeptide enrichment with immobilized titanium ion affinity chromatography adsorbent for phosphoproteome analysis. PubMed ID: 18630941

The phagosomal proteome in interferon-gamma-activated macrophages. PubMed ID: 19144319

Large scale localization of protein phosphorylation by use of electron capture dissociation mass spectrometry. PubMed ID: 19131326

A tissue-specific atlas of mouse protein phosphorylation and expression. PubMed ID: 21183079

Tom70 mediates activation of interferon regulatory factor 3 on mitochondria. PubMed ID: 20628368