Details for: ABR

Gene ID: 29

Symbol: ABR

Ensembl ID: ENSG00000159842

Description: ABR activator of RhoGEF and GTPase

Associated with

Cells (max top 100)

(Marker Scores and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

  • Cell Name: mature microglial cell (CL0002629)
    Fold Change: 4.01
    Marker Score: 1,449
  • Cell Name: pigmented epithelial cell (CL0000529)
    Fold Change: 3.23
    Marker Score: 13,528
  • Cell Name: central nervous system macrophage (CL0000878)
    Fold Change: 3.22
    Marker Score: 1,600
  • Cell Name: astrocyte of the cerebral cortex (CL0002605)
    Fold Change: 2.92
    Marker Score: 62,237
  • Cell Name: mature astrocyte (CL0002627)
    Fold Change: 2.54
    Marker Score: 1,671
  • Cell Name: sst GABAergic cortical interneuron (CL4023017)
    Fold Change: 2.49
    Marker Score: 49,500
  • Cell Name: sncg GABAergic cortical interneuron (CL4023015)
    Fold Change: 2.46
    Marker Score: 18,893
  • Cell Name: lamp5 GABAergic cortical interneuron (CL4023011)
    Fold Change: 2.45
    Marker Score: 36,566
  • Cell Name: inhibitory interneuron (CL0000498)
    Fold Change: 2.38
    Marker Score: 11,030
  • Cell Name: chandelier pvalb GABAergic cortical interneuron (CL4023036)
    Fold Change: 2.24
    Marker Score: 9,288
  • Cell Name: corneal epithelial cell (CL0000575)
    Fold Change: 2.18
    Marker Score: 2,413
  • Cell Name: pvalb GABAergic cortical interneuron (CL4023018)
    Fold Change: 2.17
    Marker Score: 80,211
  • Cell Name: caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
    Fold Change: 2.15
    Marker Score: 8,310
  • Cell Name: vip GABAergic cortical interneuron (CL4023016)
    Fold Change: 2.1
    Marker Score: 79,899
  • Cell Name: near-projecting glutamatergic cortical neuron (CL4023012)
    Fold Change: 2.02
    Marker Score: 18,978
  • Cell Name: pyramidal neuron (CL0000598)
    Fold Change: 2.01
    Marker Score: 3,373
  • Cell Name: ciliary muscle cell (CL1000443)
    Fold Change: 2
    Marker Score: 4,393
  • Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
    Fold Change: 1.97
    Marker Score: 121,031
  • Cell Name: kidney capillary endothelial cell (CL1000892)
    Fold Change: 1.95
    Marker Score: 612
  • Cell Name: regular ventricular cardiac myocyte (CL0002131)
    Fold Change: 1.91
    Marker Score: 42,696
  • Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
    Fold Change: 1.89
    Marker Score: 597
  • Cell Name: corticothalamic-projecting glutamatergic cortical neuron (CL4023013)
    Fold Change: 1.87
    Marker Score: 17,742
  • Cell Name: cerebral cortex endothelial cell (CL1001602)
    Fold Change: 1.86
    Marker Score: 1,112
  • Cell Name: OFF retinal ganglion cell (CL4023033)
    Fold Change: 1.84
    Marker Score: 769
  • Cell Name: L6b glutamatergic cortical neuron (CL4023038)
    Fold Change: 1.83
    Marker Score: 15,688
  • Cell Name: dopaminergic neuron (CL0000700)
    Fold Change: 1.81
    Marker Score: 18,707
  • Cell Name: lens epithelial cell (CL0002224)
    Fold Change: 1.72
    Marker Score: 2,078
  • Cell Name: astrocyte (CL0000127)
    Fold Change: 1.7
    Marker Score: 1,475
  • Cell Name: mononuclear cell (CL0000842)
    Fold Change: 1.64
    Marker Score: 529
  • Cell Name: regular atrial cardiac myocyte (CL0002129)
    Fold Change: 1.61
    Marker Score: 5,738
  • Cell Name: Purkinje cell (CL0000121)
    Fold Change: 1.61
    Marker Score: 54,213
  • Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
    Fold Change: 1.59
    Marker Score: 1,804
  • Cell Name: cerebral cortex neuron (CL0010012)
    Fold Change: 1.59
    Marker Score: 4,524
  • Cell Name: L5 extratelencephalic projecting glutamatergic cortical neuron (CL4023041)
    Fold Change: 1.58
    Marker Score: 2,437
  • Cell Name: neuron (CL0000540)
    Fold Change: 1.51
    Marker Score: 6,164
  • Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
    Fold Change: 1.45
    Marker Score: 423
  • Cell Name: anterior lens cell (CL0002223)
    Fold Change: 1.43
    Marker Score: 1,930
  • Cell Name: ON retinal ganglion cell (CL4023032)
    Fold Change: 1.42
    Marker Score: 389
  • Cell Name: pigmented ciliary epithelial cell (CL0002303)
    Fold Change: 1.42
    Marker Score: 483
  • Cell Name: endothelial cell of vascular tree (CL0002139)
    Fold Change: 1.39
    Marker Score: 2,019
  • Cell Name: vascular leptomeningeal cell (CL4023051)
    Fold Change: 1.38
    Marker Score: 1,592
  • Cell Name: lung goblet cell (CL1000143)
    Fold Change: 1.37
    Marker Score: 395
  • Cell Name: epithelial cell of prostate (CL0002231)
    Fold Change: 1.34
    Marker Score: 931
  • Cell Name: basal epithelial cell of prostatic duct (CL0002236)
    Fold Change: 1.29
    Marker Score: 1,142
  • Cell Name: lactocyte (CL0002325)
    Fold Change: 1.26
    Marker Score: 20,246
  • Cell Name: GABAergic interneuron (CL0011005)
    Fold Change: 1.26
    Marker Score: 483
  • Cell Name: microglial cell (CL0000129)
    Fold Change: 1.24
    Marker Score: 2,259
  • Cell Name: renal alpha-intercalated cell (CL0005011)
    Fold Change: 1.22
    Marker Score: 645
  • Cell Name: renal interstitial pericyte (CL1001318)
    Fold Change: 1.22
    Marker Score: 1,161
  • Cell Name: secondary lens fiber (CL0002225)
    Fold Change: 1.21
    Marker Score: 710
  • Cell Name: peripheral nervous system neuron (CL2000032)
    Fold Change: 1.18
    Marker Score: 1,325
  • Cell Name: Kupffer cell (CL0000091)
    Fold Change: 1.14
    Marker Score: 1,144
  • Cell Name: myeloid leukocyte (CL0000766)
    Fold Change: 1.14
    Marker Score: 1,376
  • Cell Name: contractile cell (CL0000183)
    Fold Change: 1.13
    Marker Score: 614
  • Cell Name: kidney proximal straight tubule epithelial cell (CL1000839)
    Fold Change: 1.12
    Marker Score: 2,638
  • Cell Name: kidney interstitial fibroblast (CL1000692)
    Fold Change: 1.1
    Marker Score: 2,113
  • Cell Name: enterocyte of epithelium of large intestine (CL0002071)
    Fold Change: 1.05
    Marker Score: 1,046
  • Cell Name: alveolar type 2 fibroblast cell (CL4028006)
    Fold Change: 1.04
    Marker Score: 581
  • Cell Name: bladder urothelial cell (CL1001428)
    Fold Change: 1.04
    Marker Score: 1,531
  • Cell Name: endothelial cell of pericentral hepatic sinusoid (CL0019022)
    Fold Change: 1.03
    Marker Score: 1,101
  • Cell Name: cerebellar granule cell precursor (CL0002362)
    Fold Change: 1.01
    Marker Score: 564
  • Cell Name: colon epithelial cell (CL0011108)
    Fold Change: 1
    Marker Score: 3,148
  • Cell Name: club cell (CL0000158)
    Fold Change: 1
    Marker Score: 1,170
  • Cell Name: cerebral cortex GABAergic interneuron (CL0010011)
    Fold Change: 1
    Marker Score: 71,682
  • Cell Name: forebrain radial glial cell (CL0013000)
    Fold Change: 1
    Marker Score: 47,907
  • Cell Name: lung ciliated cell (CL1000271)
    Fold Change: 0.99
    Marker Score: 471
  • Cell Name: absorptive cell (CL0000212)
    Fold Change: 0.98
    Marker Score: 30,386
  • Cell Name: brainstem motor neuron (CL2000047)
    Fold Change: 0.97
    Marker Score: 565
  • Cell Name: epicardial adipocyte (CL1000309)
    Fold Change: 0.97
    Marker Score: 469
  • Cell Name: basal cell (CL0000646)
    Fold Change: 0.96
    Marker Score: 1,235
  • Cell Name: intestinal crypt stem cell of colon (CL0009043)
    Fold Change: 0.94
    Marker Score: 2,397
  • Cell Name: smooth muscle cell of prostate (CL1000487)
    Fold Change: 0.94
    Marker Score: 239
  • Cell Name: tuft cell of colon (CL0009041)
    Fold Change: 0.92
    Marker Score: 476
  • Cell Name: endothelial cell of periportal hepatic sinusoid (CL0019021)
    Fold Change: 0.92
    Marker Score: 254
  • Cell Name: sympathetic neuron (CL0011103)
    Fold Change: 0.92
    Marker Score: 304
  • Cell Name: ciliated cell (CL0000064)
    Fold Change: 0.92
    Marker Score: 3,157
  • Cell Name: intestinal epithelial cell (CL0002563)
    Fold Change: 0.91
    Marker Score: 1,485
  • Cell Name: BEST4+ intestinal epithelial cell, human (CL4030026)
    Fold Change: 0.91
    Marker Score: 432
  • Cell Name: transit amplifying cell (CL0009010)
    Fold Change: 0.91
    Marker Score: 5,217
  • Cell Name: abnormal cell (CL0001061)
    Fold Change: 0.9
    Marker Score: 2,702
  • Cell Name: nasal mucosa goblet cell (CL0002480)
    Fold Change: 0.9
    Marker Score: 599
  • Cell Name: GABAergic neuron (CL0000617)
    Fold Change: 0.9
    Marker Score: 3,734
  • Cell Name: intestinal crypt stem cell (CL0002250)
    Fold Change: 0.89
    Marker Score: 336
  • Cell Name: lymphoid lineage restricted progenitor cell (CL0000838)
    Fold Change: 0.89
    Marker Score: 534
  • Cell Name: podocyte (CL0000653)
    Fold Change: 0.87
    Marker Score: 323
  • Cell Name: neoplastic cell (CL0001063)
    Fold Change: 0.87
    Marker Score: 5,292
  • Cell Name: connective tissue cell (CL0002320)
    Fold Change: 0.86
    Marker Score: 224
  • Cell Name: epithelial cell of small intestine (CL0002254)
    Fold Change: 0.85
    Marker Score: 307
  • Cell Name: papillary tips cell (CL1000597)
    Fold Change: 0.85
    Marker Score: 171
  • Cell Name: lymphocyte (CL0000542)
    Fold Change: 0.84
    Marker Score: 426
  • Cell Name: mesangial cell (CL0000650)
    Fold Change: 0.84
    Marker Score: 1,016
  • Cell Name: cardiac neuron (CL0010022)
    Fold Change: 0.84
    Marker Score: 1,043
  • Cell Name: kidney loop of Henle thin descending limb epithelial cell (CL1001111)
    Fold Change: 0.84
    Marker Score: 901
  • Cell Name: skeletal muscle fibroblast (CL0011027)
    Fold Change: 0.83
    Marker Score: 546
  • Cell Name: alveolar macrophage (CL0000583)
    Fold Change: 0.83
    Marker Score: 21,220
  • Cell Name: corneal endothelial cell (CL0000132)
    Fold Change: 0.83
    Marker Score: 482
  • Cell Name: conjunctival epithelial cell (CL1000432)
    Fold Change: 0.82
    Marker Score: 865
  • Cell Name: osteoclast (CL0000092)
    Fold Change: 0.81
    Marker Score: 402
  • Cell Name: keratinocyte (CL0000312)
    Fold Change: 0.81
    Marker Score: 673
  • Cell Name: macrophage (CL0000235)
    Fold Change: 0.81
    Marker Score: 896

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Marker Score to the Marker Score Threshold, indicating how much the gene expression has changed compared to a baseline.
Marker Score: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Marker Score to the Marker Score Threshold, indicating how much the gene expression has changed compared to a baseline.
Marker Score: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Marker Score to the Marker Score Threshold, indicating how much the gene expression has changed compared to a baseline.
Marker Score: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Other Information

**Key Characteristics:** ABR is a highly conserved protein that belongs to the Rho GEF family. It is primarily expressed in mature microglial cells, pigmented epithelial cells, central nervous system macrophages, astrocytes, and specific subsets of GABAergic cortical interneurons. ABR's ability to activate Rho GTPases is essential for its role in regulating small GTPase-mediated signal transduction. The gene's expression is tightly regulated, and its dysregulation has been implicated in various neurological disorders, including neurodegenerative diseases and synaptic dysfunction. **Pathways and Functions:** ABR's activation of Rho GTPases leads to the regulation of various signaling pathways, including: 1. **Axon guidance**: ABR's activation of RhoA and Rac1 promotes the formation of axonal projections and guidance, which is essential for neural development and regeneration. 2. **Cell death signaling**: ABR's activation of RhoA and Rac2 regulates cell death signaling via the NrgE/NrF/NrE3 pathway, which is involved in the regulation of apoptosis and necroptosis. 3. **Synaptic transmission**: ABR's activation of Rac1 and Rac3 regulates glutamatergic synaptic transmission, which is essential for neural communication and learning. 4. **G protein-coupled receptor signaling**: ABR's activation of RhoA and Rac1 regulates signaling events initiated by G protein-coupled receptors (GPCRs), which are involved in various cellular processes, including cell growth, differentiation, and survival. **Clinical Significance:** Dysregulation of ABR's function has been implicated in various neurological disorders, including: 1. **Neurodegenerative diseases**: ABR's dysregulation has been linked to neurodegenerative diseases, such as Alzheimer's disease, Parkinson's disease, and Huntington's disease, which are characterized by synaptic dysfunction and neuronal death. 2. **Synaptic dysfunction**: ABR's dysregulation has been implicated in synaptic dysfunction, which is a hallmark of various neurological disorders, including autism spectrum disorder, schizophrenia, and attention deficit hyperactivity disorder. 3. **Cancer**: ABR's dysregulation has been linked to cancer, particularly in the context of glioblastoma, where ABR's activation of RhoA and Rac1 promotes tumor growth and invasion. In conclusion, ABR is a critical regulator of Rho GTPase signaling in the central nervous system, and its dysregulation has been implicated in various neurological disorders. Further research is necessary to fully elucidate the role of ABR in normal and pathological processes, and to explore its potential as a therapeutic target for the treatment of neurological diseases.

Genular Protein ID: 2460095897

Symbol: ABR_HUMAN

Name: N/A

UniProtKB Accession Codes:

Database IDs:

Citations:

PubMed ID: 8262969

Title: The human active breakpoint cluster region-related gene encodes a brain protein with homology to guanine nucleotide exchange proteins and GTPase-activating proteins.

PubMed ID: 8262969

DOI: 10.1016/s0021-9258(19)74248-3

PubMed ID: 14702039

Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.

PubMed ID: 14702039

DOI: 10.1038/ng1285

PubMed ID: 8349582

Title: Human ABR encodes a protein with GAPrac activity and homology to the DBL nucleotide exchange factor domain.

PubMed ID: 8349582

DOI: 10.1016/s0021-9258(19)85281-x

PubMed ID: 16625196

Title: DNA sequence of human chromosome 17 and analysis of rearrangement in the human lineage.

PubMed ID: 16625196

DOI: 10.1038/nature04689

PubMed ID: 2587217

Title: ABR, an active BCR-related gene.

PubMed ID: 2587217

DOI: 10.1093/nar/17.21.8821

PubMed ID: 7479768

Title: Abr and Bcr are multifunctional regulators of the Rho GTP-binding protein family.

PubMed ID: 7479768

DOI: 10.1073/pnas.92.22.10282

PubMed ID: 17116687

Title: Abr and Bcr, two homologous Rac GTPase-activating proteins, control multiple cellular functions of murine macrophages.

PubMed ID: 17116687

DOI: 10.1128/mcb.00756-06

PubMed ID: 20962234

Title: Regulation of synaptic Rac1 activity, long-term potentiation maintenance, and learning and memory by BCR and ABR Rac GTPase-activating proteins.

PubMed ID: 20962234

DOI: 10.1523/jneurosci.1711-10.2010

Sequence Information:

  • Length: 859
  • Mass: 97598
  • Checksum: 3A5BE3AD2455A194
  • Sequence:
  • MEPLSHRGLP RLSWIDTLYS NFSYGTDEYD GEGNEEQKGP PEGSETMPYI DESPTMSPQL 
    SARSQGGGDG VSPTPPEGLA PGVEAGKGLE MRKLVLSGFL ASEEIYINQL EALLLPMKPL 
    KATATTSQPV LTIQQIETIF YKIQDIYEIH KEFYDNLCPK VQQWDSQVTM GHLFQKLASQ 
    LGVYKAFVDN YKVALETAEK CSQSNNQFQK ISEELKVKGP KDSKDSHTSV TMEALLYKPI 
    DRVTRSTLVL HDLLKHTPVD HPDYPLLQDA LRISQNFLSS INEDIDPRRT AVTTPKGETR 
    QLVKDGFLVE VSESSRKLRH VFLFTDVLLC AKLKKTSAGK HQQYDCKWYI PLADLVFPSP 
    EESEASPQVH PFPDHELEDM KMKISALKSE IQKEKANKGQ SRAIERLKKK MFENEFLLLL 
    NSPTIPFRIH NRNGKSYLFL LSSDYERSEW REAIQKLQKK DLQAFVLSSV ELQVLTGSCF 
    KLRTVHNIPV TSNKDDDESP GLYGFLHVIV HSAKGFKQSA NLYCTLEVDS FGYFVSKAKT 
    RVFRDTAEPK WDEEFEIELE GSQSLRILCY EKCYDKTKVN KDNNEIVDKI MGKGQIQLDP 
    QTVETKNWHT DVIEMNGIKV EFSMKFTSRD MSLKRTPSKK QTGVFGVKIS VVTKRERSKV 
    PYIVRQCVEE VEKRGIEEVG IYRISGVATD IQALKAVFDA NNKDILLMLS DMDINAIAGT 
    LKLYFRELPE PLLTDRLYPA FMEGIALSDP AAKENCMMHL LRSLPDPNLI TFLFLLEHLK 
    RVAEKEPINK MSLHNLATVF GPTLLRPSEV ESKAHLTSAA DIWSHDVMAQ VQVLLYYLQH 
    PPISFAELKR NTLYFSTDV

Genular Protein ID: 3557649304

Symbol: I3L4Y1_HUMAN

Name: N/A

UniProtKB Accession Codes:

Database IDs:

Citations:

PubMed ID: 16625196

Title: DNA sequence of human chromosome 17 and analysis of rearrangement in the human lineage.

PubMed ID: 16625196

DOI: 10.1038/nature04689

Sequence Information:

  • Length: 1118
  • Mass: 126296
  • Checksum: 28E6E6C1624CA43A
  • Sequence:
  • MWDPRAFERR WRAEFPGAEA PVPRLESVRD AERELERRRL NLERLQQVLA EEQLKASLPQ 
    AALARGGGGD SGEPGRPDPE AESPRGDPGR PDPEAESPRG DLPAGPGAAG EAGGGRSWAD 
    AVHRQLLQPQ LRFRAREDDA PLGDPQAAPG TDEGGDGGDH DFEMVDFNEK FILSHWLVAP 
    CRFGTRERAR SPRRWMHLIP GGRRPQRGTR DLEQREAEAK GRPGSPLAAE ETPGREHLPP 
    WRRRRFLRVP ERDSPGHSSP ERDSDGSRHS SDREDDFSAD FSYGTDEYDG EGNEEQKGPP 
    EGSETMPYID ESPTMSPQLS ARSQGGGDGV SPTPPEGLAP GVEAGKGLEM RKLVLSGFLA 
    SEEIYINQLE ALLLPMKPLK ATATTSQPVL TIQQIETIFY KIQDIYEIHK EFYDNLCPKV 
    QQWDSQVTMG HLFQKLASQL GVYKAFVDNY KVALETAEKC SQSNNQFQKI SEELKVKGPK 
    DSKDSHTSVT MEALLYKPID RVTRSTLVLH DLLKHTPVDH PDYPLLQDAL RISQNFLSSI 
    NEDIDPRRTA VTTPKGETRQ LVKDGFLVEV SESSRKLRHV FLFTDVLLCA KLKKTSAGKH 
    QQYDCKWYIP LADLVFPSPE ESEASPQVHP FPDHELEDMK MKISALKSEI QKEKANKGQS 
    RAIERLKKKM FENEFLLLLN SPTIPFRIHN RNGKSYLFLL SSDYERSEWR EAIQKLQKKD 
    LQAFVLSSVE LQVLTGSCFK LRTVHNIPVT SNKDDDESPG LYGFLHVIVH SAKGFKQSAN 
    LYCTLEVDSF GYFVSKAKTR VFRDTAEPKW DEEFEIELEG SQSLRILCYE KCYDKTKVNK 
    DNNEIVDKIM GKGQIQLDPQ TVETKNWHTD VIEMNGIKVE FSMKFTSRDM SLKRTPSKKQ 
    TGVFGVKISV VTKRERSKVP YIVRQCVEEV EKRGIEEVGI YRISGVATDI QALKAVFDAN 
    NKDILLMLSD MDINAIAGTL KLYFRELPEP LLTDRLYPAF MEGIALSDPA AKENCMMHLL 
    RSLPDPNLIT FLFLLEHLKR VAEKEPINKM SLHNLATVFG PTLLRPSEVE SKAHLTSAAD 
    IWSHDVMAQV QVLLYYLQHP PISFAELKRN TLYFSTDV

Genular Protein ID: 1660933203

Symbol: B7Z7Z1_HUMAN

Name: N/A

UniProtKB Accession Codes:

Database IDs:

Sequence Information:

  • Length: 813
  • Mass: 92397
  • Checksum: FE5F70FFF4B4F5C5
  • Sequence:
  • MPYIDESPTM SPQLSARSQG GGDGVSPTPP EGLAPGVEAG KGLEMRKLVL SGFLASEEIY 
    INQLEALLLP MKPLKATATT SQPVLTIQQI ETIFYKIQDI YEIHKEFYDN LCPKVQQWDS 
    QVTMGHLFQK LASQLGVYKA FVDNYKVALE TAEKCSQSNN QFQKISEELK VKGPKDSKDS 
    HTSVTMEALL YKPIDRVTRS TLVLHDLLKH TPVDHPDYPL LQDALRISQN FLSSINEDID 
    PRRTAVTTPK GETRQLVKDG FLVEVSESSR KLRHVFLFTD VLLCAKLKKT SAGKHQQYDC 
    KWYIPLADLV FPSPEESEAS PQVHPFPDHE LEDMKMKISA LKSEIQKEKA NKGQSRAIER 
    LKKKMFENEF LLLLNSPTIP FRIHNRNGKS YLFLLSSDYE RSEWREAIQK LQKKDLQAFV 
    LSSVELQVLT GSCFKLRTVH NIPVTSNKDD DESPGLYGFL HVIVHSAKGF KQSANLYCTL 
    EVDSFGYFVS KAKTRVFRDT AEPKWDEEFE IELEGSQSLR ILCYEKCYDK TKVNKDNNEI 
    VDKIMGKGQI QLDPQTVETK NWHTDVIEMN GIKVEFSMKF TSRDMSLKRT PSKKQTGVFG 
    VKISVVTKRE RSKVPYIVRQ CVEEVEKRGI EEVGIYRISG VATDIQALKA VFDANNKDIL 
    LMLSDMDINA IAGTLKLYFR ELPEPLLTDR LYPAFMEGIA LSDPAAKENC MMHLLRSLPD 
    PNLITFLFLL EHLKRVAEKE PINKMSLHNL ATAFGPTLLR PSEVESKAHL TSAADIWSHD 
    VMAQVQVLLY YLQHPPISFA ELKRNTLYFS TDV

Genular Protein ID: 4175720552

Symbol: B7Z2X0_HUMAN

Name: N/A

UniProtKB Accession Codes:

Database IDs:

Sequence Information:

  • Length: 769
  • Mass: 88075
  • Checksum: 967A05498C2E23F7
  • Sequence:
  • MRKLVLSGFL ASEEIYINQL EALLLPMKPL KATATTSQPV LTIQQIETIF YKIQDIYEIH 
    KEFYDNLCPK VQQWDSQVTM GHLFQKLASQ LGVYKAFVDN YKVALETAEK CSQSNNQFQK 
    ISEELKVKGP KDSKDSHTSV TMEALLYKPI DRVTRSTLVL HDLLKHTPVD HPDYPLLQDA 
    LRISQNFLSS INEDIDPRRT AVTTPKGETR QLVKDGFLVE VSESSRKLRH VFLFTDVLLC 
    AKLKKTSAGK HQQYDCKWYI PLADLVFPSP EESEASPQVH PFPDHELEDM KMKISALKSE 
    IQKEKANKGQ SRAIERLKKK MFENEFLLLL NSPTIPFRIH NRNGKSYLFL LSSDYERSEW 
    REAIQKLQKK DLQAFVLSSV ELQVLTGSCF KLRTVHNIPV TSNKDDDESP GLYGFLHVIV 
    HSAKGFKQSA NLYCTLEVDS FGYFVSKAKT RVFRDTAEPK WDEEFEIELE GSQSLRILCY 
    EKCYDKTKVN KDNNEIVDKI MGKGQIQLDP QTVETKNWHT DVIEMNGIKV EFSMKFTSRD 
    MSLKRTPSKK QTGVFGVKIS VVTKRERSKV PYIVRQCVEE VEKRGIEEVG IYRISGVATD 
    IQALKAVFDA NNKDILLMLS DMDINAIAGT LKLYFRELPE PLLTDRLYPA FMEGIALSDP 
    AAKENCMMHL LRSLPDPNLI TFLFLLEHLK RVAEKEPINK MSLHNLATVF GPTLLRPSEV 
    ESKAHLTSAA DIWSHDVMAQ VQVLLYYLQH PPISFAELKR NTLYFSTDV

Genular Protein ID: 1460877146

Symbol: Q6ZT60_HUMAN

Name: N/A

UniProtKB Accession Codes:

Database IDs:

Sequence Information:

  • Length: 362
  • Mass: 41155
  • Checksum: 6DD596C803BFD4E7
  • Sequence:
  • MKPLKATATT SQPVLTIQQI ETIFYKIQDI YEIHKEFYDN LCPKVQQWDS QVTMGHLFQK 
    LASQLGVYKA FVDNYKVALE TAEKCSQSNN QFQKISEELK VKGPKDSKDS HTSVTMEALL 
    YKPIDRVTRS TLVLHDLLKH TPVDHPDYPL LQDALRISQN FLSSINEDID PRRTAVTTPK 
    GETRQLVKDG FLVEVSESSR KLRHVFLFTD VLLCAKLKKT SAGKHQQYDC KWYIPLADLV 
    FPSPEESEAS PQVHPFPDHE LEDMKMKISA LKSEIQKEVE KRGIEEVGIY RISGVATDIQ 
    ALKAVFDANN KDILLMLSDM DINAIAGTLK LYFRELPEPL LTDRLRPCPT PTSSPSSSCW 
    NT

Genular Protein ID: 4222051928

Symbol: B7Z683_HUMAN

Name: N/A

UniProtKB Accession Codes:

Database IDs:

Citations:

PubMed ID: 16625196

Title: DNA sequence of human chromosome 17 and analysis of rearrangement in the human lineage.

PubMed ID: 16625196

DOI: 10.1038/nature04689

Sequence Information:

  • Length: 641
  • Mass: 73517
  • Checksum: FE84A80387020D68
  • Sequence:
  • MEILLIIRFC CNCTYALLYK PIDRVTRSTL VLHDLLKHTP VDHPDYPLLQ DALRISQNFL 
    SSINEDIDPR RTAVTTPKGE TRQLVKDGFL VEVSESSRKL RHVFLFTDVL LCAKLKKTSA 
    GKHQQYDCKW YIPLADLVFP SPEESEASPQ VHPFPDHELE DMKMKISALK SEIQKEKANK 
    GQSRAIERLK KKMFENEFLL LLNSPTIPFR IHNRNGKSYL FLLSSDYERS EWREAIQKLQ 
    KKDLQAFVLS SVELQVLTGS CFKLRTVHNI PVTSNKDDDE SPGLYGFLHV IVHSAKGFKQ 
    SANLYCTLEV DSFGYFVSKA KTRVFRDTAE PKWDEEFEIE LEGSQSLRIL CYEKCYDKTK 
    VNKDNNEIVD KIMGKGQIQL DPQTVETKNW HTDVIEMNGI KVEFSMKFTS RDMSLKRTPS 
    KKQTGVFGVK ISVVTKRERS KVPYIVRQCV EEVEKRGIEE VGIYRISGVA TDIQALKAVF 
    DANNKDILLM LSDMDINAIA GTLKLYFREL PEPLLTDRLY PAFMEGIALS DPAAKENCMM 
    HLLRSLPDPN LITFLFLLEH LKRVAEKEPI NKMSLHNLAT VFGPTLLRPS EVESKAHLTS 
    AADIWSHDVM AQVQVLLYYL QHPPISFAEL KRNTLYFSTD V

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.