Details for: ABR

Gene ID: 29

Symbol: ABR

Ensembl ID: ENSG00000159842

Description: ABR activator of RhoGEF and GTPase

Associated with

Cells (max top 100)

(Marker Score score is uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

  • Cell Name: mature microglial cell (CL0002629)
    Fold Change: 4.01
    Marker Score: 1449
  • Cell Name: pigmented epithelial cell (CL0000529)
    Fold Change: 3.23
    Marker Score: 13528
  • Cell Name: central nervous system macrophage (CL0000878)
    Fold Change: 3.22
    Marker Score: 1600
  • Cell Name: astrocyte of the cerebral cortex (CL0002605)
    Fold Change: 2.92
    Marker Score: 62237
  • Cell Name: mature astrocyte (CL0002627)
    Fold Change: 2.54
    Marker Score: 1671
  • Cell Name: sst GABAergic cortical interneuron (CL4023017)
    Fold Change: 2.49
    Marker Score: 49500
  • Cell Name: sncg GABAergic cortical interneuron (CL4023015)
    Fold Change: 2.46
    Marker Score: 18893
  • Cell Name: lamp5 GABAergic cortical interneuron (CL4023011)
    Fold Change: 2.45
    Marker Score: 36566
  • Cell Name: inhibitory interneuron (CL0000498)
    Fold Change: 2.38
    Marker Score: 11030
  • Cell Name: chandelier pvalb GABAergic cortical interneuron (CL4023036)
    Fold Change: 2.24
    Marker Score: 9288
  • Cell Name: corneal epithelial cell (CL0000575)
    Fold Change: 2.18
    Marker Score: 2413
  • Cell Name: pvalb GABAergic cortical interneuron (CL4023018)
    Fold Change: 2.17
    Marker Score: 80211
  • Cell Name: caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
    Fold Change: 2.15
    Marker Score: 8310
  • Cell Name: vip GABAergic cortical interneuron (CL4023016)
    Fold Change: 2.1
    Marker Score: 79899
  • Cell Name: near-projecting glutamatergic cortical neuron (CL4023012)
    Fold Change: 2.02
    Marker Score: 18978
  • Cell Name: pyramidal neuron (CL0000598)
    Fold Change: 2.01
    Marker Score: 3373
  • Cell Name: ciliary muscle cell (CL1000443)
    Fold Change: 2
    Marker Score: 4393
  • Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
    Fold Change: 1.97
    Marker Score: 121031
  • Cell Name: kidney capillary endothelial cell (CL1000892)
    Fold Change: 1.95
    Marker Score: 612
  • Cell Name: regular ventricular cardiac myocyte (CL0002131)
    Fold Change: 1.91
    Marker Score: 42696
  • Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
    Fold Change: 1.89
    Marker Score: 597
  • Cell Name: corticothalamic-projecting glutamatergic cortical neuron (CL4023013)
    Fold Change: 1.87
    Marker Score: 17742
  • Cell Name: cerebral cortex endothelial cell (CL1001602)
    Fold Change: 1.86
    Marker Score: 1112
  • Cell Name: OFF retinal ganglion cell (CL4023033)
    Fold Change: 1.84
    Marker Score: 769
  • Cell Name: L6b glutamatergic cortical neuron (CL4023038)
    Fold Change: 1.83
    Marker Score: 15688
  • Cell Name: dopaminergic neuron (CL0000700)
    Fold Change: 1.81
    Marker Score: 18707
  • Cell Name: lens epithelial cell (CL0002224)
    Fold Change: 1.72
    Marker Score: 2078
  • Cell Name: astrocyte (CL0000127)
    Fold Change: 1.7
    Marker Score: 1475
  • Cell Name: mononuclear cell (CL0000842)
    Fold Change: 1.64
    Marker Score: 529
  • Cell Name: regular atrial cardiac myocyte (CL0002129)
    Fold Change: 1.61
    Marker Score: 5738
  • Cell Name: Purkinje cell (CL0000121)
    Fold Change: 1.61
    Marker Score: 54213
  • Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
    Fold Change: 1.59
    Marker Score: 1804
  • Cell Name: cerebral cortex neuron (CL0010012)
    Fold Change: 1.59
    Marker Score: 4523.5
  • Cell Name: L5 extratelencephalic projecting glutamatergic cortical neuron (CL4023041)
    Fold Change: 1.58
    Marker Score: 2437
  • Cell Name: neuron (CL0000540)
    Fold Change: 1.51
    Marker Score: 6164
  • Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
    Fold Change: 1.45
    Marker Score: 423
  • Cell Name: anterior lens cell (CL0002223)
    Fold Change: 1.43
    Marker Score: 1930
  • Cell Name: ON retinal ganglion cell (CL4023032)
    Fold Change: 1.42
    Marker Score: 389
  • Cell Name: pigmented ciliary epithelial cell (CL0002303)
    Fold Change: 1.42
    Marker Score: 483
  • Cell Name: endothelial cell of vascular tree (CL0002139)
    Fold Change: 1.39
    Marker Score: 2019
  • Cell Name: vascular leptomeningeal cell (CL4023051)
    Fold Change: 1.38
    Marker Score: 1592
  • Cell Name: lung goblet cell (CL1000143)
    Fold Change: 1.37
    Marker Score: 395
  • Cell Name: epithelial cell of prostate (CL0002231)
    Fold Change: 1.34
    Marker Score: 931
  • Cell Name: basal epithelial cell of prostatic duct (CL0002236)
    Fold Change: 1.29
    Marker Score: 1142
  • Cell Name: lactocyte (CL0002325)
    Fold Change: 1.26
    Marker Score: 20246
  • Cell Name: GABAergic interneuron (CL0011005)
    Fold Change: 1.26
    Marker Score: 483
  • Cell Name: microglial cell (CL0000129)
    Fold Change: 1.24
    Marker Score: 2259
  • Cell Name: renal alpha-intercalated cell (CL0005011)
    Fold Change: 1.22
    Marker Score: 645
  • Cell Name: renal interstitial pericyte (CL1001318)
    Fold Change: 1.22
    Marker Score: 1161
  • Cell Name: secondary lens fiber (CL0002225)
    Fold Change: 1.21
    Marker Score: 710
  • Cell Name: peripheral nervous system neuron (CL2000032)
    Fold Change: 1.18
    Marker Score: 1324.5
  • Cell Name: Kupffer cell (CL0000091)
    Fold Change: 1.14
    Marker Score: 1143.5
  • Cell Name: myeloid leukocyte (CL0000766)
    Fold Change: 1.14
    Marker Score: 1376
  • Cell Name: contractile cell (CL0000183)
    Fold Change: 1.13
    Marker Score: 614
  • Cell Name: kidney proximal straight tubule epithelial cell (CL1000839)
    Fold Change: 1.12
    Marker Score: 2638
  • Cell Name: kidney interstitial fibroblast (CL1000692)
    Fold Change: 1.1
    Marker Score: 2112.5
  • Cell Name: enterocyte of epithelium of large intestine (CL0002071)
    Fold Change: 1.05
    Marker Score: 1045.5
  • Cell Name: alveolar type 2 fibroblast cell (CL4028006)
    Fold Change: 1.04
    Marker Score: 581
  • Cell Name: bladder urothelial cell (CL1001428)
    Fold Change: 1.04
    Marker Score: 1531
  • Cell Name: endothelial cell of pericentral hepatic sinusoid (CL0019022)
    Fold Change: 1.03
    Marker Score: 1101
  • Cell Name: cerebellar granule cell precursor (CL0002362)
    Fold Change: 1.01
    Marker Score: 564
  • Cell Name: colon epithelial cell (CL0011108)
    Fold Change: 1
    Marker Score: 3148
  • Cell Name: club cell (CL0000158)
    Fold Change: 1
    Marker Score: 1170
  • Cell Name: cerebral cortex GABAergic interneuron (CL0010011)
    Fold Change: 1
    Marker Score: 71682
  • Cell Name: forebrain radial glial cell (CL0013000)
    Fold Change: 1
    Marker Score: 47907
  • Cell Name: lung ciliated cell (CL1000271)
    Fold Change: 0.99
    Marker Score: 471
  • Cell Name: absorptive cell (CL0000212)
    Fold Change: 0.98
    Marker Score: 30386
  • Cell Name: brainstem motor neuron (CL2000047)
    Fold Change: 0.97
    Marker Score: 565
  • Cell Name: epicardial adipocyte (CL1000309)
    Fold Change: 0.97
    Marker Score: 469
  • Cell Name: basal cell (CL0000646)
    Fold Change: 0.96
    Marker Score: 1235
  • Cell Name: intestinal crypt stem cell of colon (CL0009043)
    Fold Change: 0.94
    Marker Score: 2397
  • Cell Name: smooth muscle cell of prostate (CL1000487)
    Fold Change: 0.94
    Marker Score: 239
  • Cell Name: tuft cell of colon (CL0009041)
    Fold Change: 0.92
    Marker Score: 476
  • Cell Name: endothelial cell of periportal hepatic sinusoid (CL0019021)
    Fold Change: 0.92
    Marker Score: 254
  • Cell Name: sympathetic neuron (CL0011103)
    Fold Change: 0.92
    Marker Score: 304
  • Cell Name: ciliated cell (CL0000064)
    Fold Change: 0.92
    Marker Score: 3157
  • Cell Name: intestinal epithelial cell (CL0002563)
    Fold Change: 0.91
    Marker Score: 1485
  • Cell Name: BEST4+ intestinal epithelial cell, human (CL4030026)
    Fold Change: 0.91
    Marker Score: 432
  • Cell Name: transit amplifying cell (CL0009010)
    Fold Change: 0.91
    Marker Score: 5217
  • Cell Name: abnormal cell (CL0001061)
    Fold Change: 0.9
    Marker Score: 2702
  • Cell Name: nasal mucosa goblet cell (CL0002480)
    Fold Change: 0.9
    Marker Score: 599
  • Cell Name: GABAergic neuron (CL0000617)
    Fold Change: 0.9
    Marker Score: 3734
  • Cell Name: intestinal crypt stem cell (CL0002250)
    Fold Change: 0.89
    Marker Score: 335.5
  • Cell Name: lymphoid lineage restricted progenitor cell (CL0000838)
    Fold Change: 0.89
    Marker Score: 534
  • Cell Name: podocyte (CL0000653)
    Fold Change: 0.87
    Marker Score: 323
  • Cell Name: neoplastic cell (CL0001063)
    Fold Change: 0.87
    Marker Score: 5292
  • Cell Name: connective tissue cell (CL0002320)
    Fold Change: 0.86
    Marker Score: 224
  • Cell Name: epithelial cell of small intestine (CL0002254)
    Fold Change: 0.85
    Marker Score: 307
  • Cell Name: papillary tips cell (CL1000597)
    Fold Change: 0.85
    Marker Score: 171
  • Cell Name: lymphocyte (CL0000542)
    Fold Change: 0.84
    Marker Score: 426
  • Cell Name: mesangial cell (CL0000650)
    Fold Change: 0.84
    Marker Score: 1016
  • Cell Name: cardiac neuron (CL0010022)
    Fold Change: 0.84
    Marker Score: 1043
  • Cell Name: kidney loop of Henle thin descending limb epithelial cell (CL1001111)
    Fold Change: 0.84
    Marker Score: 901
  • Cell Name: skeletal muscle fibroblast (CL0011027)
    Fold Change: 0.83
    Marker Score: 546
  • Cell Name: alveolar macrophage (CL0000583)
    Fold Change: 0.83
    Marker Score: 21220
  • Cell Name: corneal endothelial cell (CL0000132)
    Fold Change: 0.83
    Marker Score: 482
  • Cell Name: conjunctival epithelial cell (CL1000432)
    Fold Change: 0.82
    Marker Score: 865
  • Cell Name: osteoclast (CL0000092)
    Fold Change: 0.81
    Marker Score: 402
  • Cell Name: keratinocyte (CL0000312)
    Fold Change: 0.81
    Marker Score: 673
  • Cell Name: macrophage (CL0000235)
    Fold Change: 0.81
    Marker Score: 896

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Other Information

**Key characteristics:** - The ABR gene is a member of the RhoGEF family of guanosine triphosphate (GTP)-binding proteins. - It is a key regulator of cell death signaling pathways, including the cdc42 gtpase, nrage, nrif, and nade pathways. - It is also involved in the G alpha (12/13) signaling events, Gpcr downstream signaling, Guanyl-nucleotide exchange factor activity, and Nrage signals death through jnk, P75 ntr receptor-mediated signaling, Rac1 gtpase cycle, Rac2 gtpase cycle, Rac3 gtpase cycle, Rhoa gtpase cycle, Rhob gtpase cycle, Rho gtpase cycle, and signaling by gpcr. **Pathways and functions:** - Activation of the ABR gene leads to the activation of the RhoGEF and GTPase signaling pathways. - These pathways are involved in cell cycle regulation, apoptosis, and inflammation. - In the context of cell death, ABR signaling promotes cell death through the cdc42 gtpase, nrage, nrif, and nade pathways. - It also plays a role in promoting cell death in response to various stimuli, including ischemia, oxidative stress, and neurotoxic agents. **Clinical significance:** - Aberrant expression of the ABR gene has been linked to various neurological diseases, including multiple sclerosis, Parkinson's disease, and Alzheimer's disease. - Targeting the ABR gene has been explored as a therapeutic strategy for these diseases. - However, the development of effective anti-ABR therapies has proven challenging due to the complex and multifaceted nature of the disease.

Genular Protein ID: 2460095897

Symbol: ABR_HUMAN

Name: N/A

UniProtKB Accession Codes:

Q12979 B3KW89 B7Z6H7 D3DTH3 D3DTH4 F5H3S2 F5H8B3 Q13693 Q13694

Database IDs:

AGR 1 AlphaFoldDB 1 Antibodypedia 1 Bgee 1 BioGRID 1 BioGRID-ORCS 1 BioMuta 1 CCDS 4 CDD 4 CTD 1 ChiTaRS 1 DMDM 1 DNASU 1 DisGeNET 1 EMBL 12 EPD 1 Ensembl 11 ExpressionAtlas 1 GO 12 Gene3D 4 GeneCards 1 GeneTree 1 Genevisible 1 GenomeRNAi 1 HGNC 2 HOGENOM 1 HPA 1 InParanoid 1 IntAct 1 InterPro 11 KEGG 1 MANE-Select 1 MIM 1 MINT 1 MassIVE 1 MaxQB 1 NCBI Taxonomy 1 OMA 1 OpenTargets 1 OrthoDB 1 PANTHER 2 PIR 2 PRO 1 PROSITE 5 PROSITE-ProRule 4 PathwayCommons 1 PaxDb 1 PeptideAtlas 1 Pfam 4 PharmGKB 1 Pharos 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 4 Pumba 1 RNAct 1 Reactome 9 RefSeq 6 SAM 1 SIGNOR 1 SMART 4 SMR 1 STRING 1 SUPFAM 4 SignaLink 1 TreeFam 1 UCSC 1 UniProtKB 2 VEuPathDB 1 eggNOG 1 iPTMnet 1 jPOST 1 neXtProt 1

Citations:

PubMed ID: 8262969

Title: The human active breakpoint cluster region-related gene encodes a brain protein with homology to guanine nucleotide exchange proteins and GTPase-activating proteins.

PubMed ID: 8262969

DOI: 10.1016/s0021-9258(19)74248-3

PubMed ID: 14702039

Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.

PubMed ID: 14702039

DOI: 10.1038/ng1285

PubMed ID: 8349582

Title: Human ABR encodes a protein with GAPrac activity and homology to the DBL nucleotide exchange factor domain.

PubMed ID: 8349582

DOI: 10.1016/s0021-9258(19)85281-x

PubMed ID: 16625196

Title: DNA sequence of human chromosome 17 and analysis of rearrangement in the human lineage.

PubMed ID: 16625196

DOI: 10.1038/nature04689

PubMed ID: 2587217

Title: ABR, an active BCR-related gene.

PubMed ID: 2587217

DOI: 10.1093/nar/17.21.8821

PubMed ID: 7479768

Title: Abr and Bcr are multifunctional regulators of the Rho GTP-binding protein family.

PubMed ID: 7479768

DOI: 10.1073/pnas.92.22.10282

PubMed ID: 17116687

Title: Abr and Bcr, two homologous Rac GTPase-activating proteins, control multiple cellular functions of murine macrophages.

PubMed ID: 17116687

DOI: 10.1128/mcb.00756-06

PubMed ID: 20962234

Title: Regulation of synaptic Rac1 activity, long-term potentiation maintenance, and learning and memory by BCR and ABR Rac GTPase-activating proteins.

PubMed ID: 20962234

DOI: 10.1523/jneurosci.1711-10.2010

Sequence Information:

  • Length: 859
  • Mass: 97598
  • Checksum: 3A5BE3AD2455A194
  • Sequence:
    • MEPLSHRGLP RLSWIDTLYS NFSYGTDEYD GEGNEEQKGP PEGSETMPYI DESPTMSPQL 
SARSQGGGDG VSPTPPEGLA PGVEAGKGLE MRKLVLSGFL ASEEIYINQL EALLLPMKPL 
KATATTSQPV LTIQQIETIF YKIQDIYEIH KEFYDNLCPK VQQWDSQVTM GHLFQKLASQ 
LGVYKAFVDN YKVALETAEK CSQSNNQFQK ISEELKVKGP KDSKDSHTSV TMEALLYKPI 
DRVTRSTLVL HDLLKHTPVD HPDYPLLQDA LRISQNFLSS INEDIDPRRT AVTTPKGETR 
QLVKDGFLVE VSESSRKLRH VFLFTDVLLC AKLKKTSAGK HQQYDCKWYI PLADLVFPSP 
EESEASPQVH PFPDHELEDM KMKISALKSE IQKEKANKGQ SRAIERLKKK MFENEFLLLL 
NSPTIPFRIH NRNGKSYLFL LSSDYERSEW REAIQKLQKK DLQAFVLSSV ELQVLTGSCF 
KLRTVHNIPV TSNKDDDESP GLYGFLHVIV HSAKGFKQSA NLYCTLEVDS FGYFVSKAKT 
RVFRDTAEPK WDEEFEIELE GSQSLRILCY EKCYDKTKVN KDNNEIVDKI MGKGQIQLDP 
QTVETKNWHT DVIEMNGIKV EFSMKFTSRD MSLKRTPSKK QTGVFGVKIS VVTKRERSKV 
PYIVRQCVEE VEKRGIEEVG IYRISGVATD IQALKAVFDA NNKDILLMLS DMDINAIAGT 
LKLYFRELPE PLLTDRLYPA FMEGIALSDP AAKENCMMHL LRSLPDPNLI TFLFLLEHLK 
RVAEKEPINK MSLHNLATVF GPTLLRPSEV ESKAHLTSAA DIWSHDVMAQ VQVLLYYLQH 
PPISFAELKR NTLYFSTDV

Genular Protein ID: 3557649304

Symbol: I3L4Y1_HUMAN

Name: N/A

UniProtKB Accession Codes:

I3L4Y1

Database IDs:

ARBA 8 AlphaFoldDB 1 Antibodypedia 1 Bgee 1 CDD 4 CTD 1 ChiTaRS 1 EMBL 4 EPD 1 Ensembl 2 ExpressionAtlas 1 GO 6 Gene3D 5 GeneTree 1 HGNC 1 HOGENOM 1 InterPro 13 MassIVE 1 MaxQB 2 NCBI Taxonomy 1 PANTHER 2 PROSITE 9 Pfam 5 Proteomes 2 ProteomicsDB 1 RefSeq 1 SAM 2 SMART 4 SMR 1 SUPFAM 5 UCSC 1 VEuPathDB 1

Citations:

PubMed ID: 16625196

Title: DNA sequence of human chromosome 17 and analysis of rearrangement in the human lineage.

PubMed ID: 16625196

DOI: 10.1038/nature04689

Sequence Information:

  • Length: 1118
  • Mass: 126296
  • Checksum: 28E6E6C1624CA43A
  • Sequence:
    • MWDPRAFERR WRAEFPGAEA PVPRLESVRD AERELERRRL NLERLQQVLA EEQLKASLPQ 
AALARGGGGD SGEPGRPDPE AESPRGDPGR PDPEAESPRG DLPAGPGAAG EAGGGRSWAD 
AVHRQLLQPQ LRFRAREDDA PLGDPQAAPG TDEGGDGGDH DFEMVDFNEK FILSHWLVAP 
CRFGTRERAR SPRRWMHLIP GGRRPQRGTR DLEQREAEAK GRPGSPLAAE ETPGREHLPP 
WRRRRFLRVP ERDSPGHSSP ERDSDGSRHS SDREDDFSAD FSYGTDEYDG EGNEEQKGPP 
EGSETMPYID ESPTMSPQLS ARSQGGGDGV SPTPPEGLAP GVEAGKGLEM RKLVLSGFLA 
SEEIYINQLE ALLLPMKPLK ATATTSQPVL TIQQIETIFY KIQDIYEIHK EFYDNLCPKV 
QQWDSQVTMG HLFQKLASQL GVYKAFVDNY KVALETAEKC SQSNNQFQKI SEELKVKGPK 
DSKDSHTSVT MEALLYKPID RVTRSTLVLH DLLKHTPVDH PDYPLLQDAL RISQNFLSSI 
NEDIDPRRTA VTTPKGETRQ LVKDGFLVEV SESSRKLRHV FLFTDVLLCA KLKKTSAGKH 
QQYDCKWYIP LADLVFPSPE ESEASPQVHP FPDHELEDMK MKISALKSEI QKEKANKGQS 
RAIERLKKKM FENEFLLLLN SPTIPFRIHN RNGKSYLFLL SSDYERSEWR EAIQKLQKKD 
LQAFVLSSVE LQVLTGSCFK LRTVHNIPVT SNKDDDESPG LYGFLHVIVH SAKGFKQSAN 
LYCTLEVDSF GYFVSKAKTR VFRDTAEPKW DEEFEIELEG SQSLRILCYE KCYDKTKVNK 
DNNEIVDKIM GKGQIQLDPQ TVETKNWHTD VIEMNGIKVE FSMKFTSRDM SLKRTPSKKQ 
TGVFGVKISV VTKRERSKVP YIVRQCVEEV EKRGIEEVGI YRISGVATDI QALKAVFDAN 
NKDILLMLSD MDINAIAGTL KLYFRELPEP LLTDRLYPAF MEGIALSDPA AKENCMMHLL 
RSLPDPNLIT FLFLLEHLKR VAEKEPINKM SLHNLATVFG PTLLRPSEVE SKAHLTSAAD 
IWSHDVMAQV QVLLYYLQHP PISFAELKRN TLYFSTDV

Genular Protein ID: 1660933203

Symbol: B7Z7Z1_HUMAN

Name: N/A

UniProtKB Accession Codes:

B7Z7Z1

Database IDs:

ARBA 8 AlphaFoldDB 1 BioGRID-ORCS 1 CDD 4 CTD 1 DNASU 1 EMBL 2 GO 5 Gene3D 4 GenomeRNAi 1 InterPro 11 KEGG 1 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PROSITE 9 PeptideAtlas 1 Pfam 4 RefSeq 4 SAM 1 SMART 4 SUPFAM 4

Sequence Information:

  • Length: 813
  • Mass: 92397
  • Checksum: FE5F70FFF4B4F5C5
  • Sequence:
    • MPYIDESPTM SPQLSARSQG GGDGVSPTPP EGLAPGVEAG KGLEMRKLVL SGFLASEEIY 
INQLEALLLP MKPLKATATT SQPVLTIQQI ETIFYKIQDI YEIHKEFYDN LCPKVQQWDS 
QVTMGHLFQK LASQLGVYKA FVDNYKVALE TAEKCSQSNN QFQKISEELK VKGPKDSKDS 
HTSVTMEALL YKPIDRVTRS TLVLHDLLKH TPVDHPDYPL LQDALRISQN FLSSINEDID 
PRRTAVTTPK GETRQLVKDG FLVEVSESSR KLRHVFLFTD VLLCAKLKKT SAGKHQQYDC 
KWYIPLADLV FPSPEESEAS PQVHPFPDHE LEDMKMKISA LKSEIQKEKA NKGQSRAIER 
LKKKMFENEF LLLLNSPTIP FRIHNRNGKS YLFLLSSDYE RSEWREAIQK LQKKDLQAFV 
LSSVELQVLT GSCFKLRTVH NIPVTSNKDD DESPGLYGFL HVIVHSAKGF KQSANLYCTL 
EVDSFGYFVS KAKTRVFRDT AEPKWDEEFE IELEGSQSLR ILCYEKCYDK TKVNKDNNEI 
VDKIMGKGQI QLDPQTVETK NWHTDVIEMN GIKVEFSMKF TSRDMSLKRT PSKKQTGVFG 
VKISVVTKRE RSKVPYIVRQ CVEEVEKRGI EEVGIYRISG VATDIQALKA VFDANNKDIL 
LMLSDMDINA IAGTLKLYFR ELPEPLLTDR LYPAFMEGIA LSDPAAKENC MMHLLRSLPD 
PNLITFLFLL EHLKRVAEKE PINKMSLHNL ATAFGPTLLR PSEVESKAHL TSAADIWSHD 
VMAQVQVLLY YLQHPPISFA ELKRNTLYFS TDV

Genular Protein ID: 4175720552

Symbol: B7Z2X0_HUMAN

Name: N/A

UniProtKB Accession Codes:

B7Z2X0

Database IDs:

ARBA 8 AlphaFoldDB 1 BioGRID-ORCS 1 CDD 4 CTD 1 DNASU 1 EMBL 2 GO 5 Gene3D 4 GenomeRNAi 1 InterPro 11 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PROSITE 9 PeptideAtlas 1 Pfam 4 RefSeq 1 SMART 4 SUPFAM 4

Sequence Information:

  • Length: 769
  • Mass: 88075
  • Checksum: 967A05498C2E23F7
  • Sequence:
    • MRKLVLSGFL ASEEIYINQL EALLLPMKPL KATATTSQPV LTIQQIETIF YKIQDIYEIH 
KEFYDNLCPK VQQWDSQVTM GHLFQKLASQ LGVYKAFVDN YKVALETAEK CSQSNNQFQK 
ISEELKVKGP KDSKDSHTSV TMEALLYKPI DRVTRSTLVL HDLLKHTPVD HPDYPLLQDA 
LRISQNFLSS INEDIDPRRT AVTTPKGETR QLVKDGFLVE VSESSRKLRH VFLFTDVLLC 
AKLKKTSAGK HQQYDCKWYI PLADLVFPSP EESEASPQVH PFPDHELEDM KMKISALKSE 
IQKEKANKGQ SRAIERLKKK MFENEFLLLL NSPTIPFRIH NRNGKSYLFL LSSDYERSEW 
REAIQKLQKK DLQAFVLSSV ELQVLTGSCF KLRTVHNIPV TSNKDDDESP GLYGFLHVIV 
HSAKGFKQSA NLYCTLEVDS FGYFVSKAKT RVFRDTAEPK WDEEFEIELE GSQSLRILCY 
EKCYDKTKVN KDNNEIVDKI MGKGQIQLDP QTVETKNWHT DVIEMNGIKV EFSMKFTSRD 
MSLKRTPSKK QTGVFGVKIS VVTKRERSKV PYIVRQCVEE VEKRGIEEVG IYRISGVATD 
IQALKAVFDA NNKDILLMLS DMDINAIAGT LKLYFRELPE PLLTDRLYPA FMEGIALSDP 
AAKENCMMHL LRSLPDPNLI TFLFLLEHLK RVAEKEPINK MSLHNLATVF GPTLLRPSEV 
ESKAHLTSAA DIWSHDVMAQ VQVLLYYLQH PPISFAELKR NTLYFSTDV

Genular Protein ID: 1460877146

Symbol: Q6ZT60_HUMAN

Name: N/A

UniProtKB Accession Codes:

Q6ZT60

Database IDs:

ARBA 1 AlphaFoldDB 1 BioGRID-ORCS 1 CDD 1 CTD 1 DNASU 1 EMBL 2 GO 4 Gene3D 3 Genevisible 1 GenomeRNAi 1 InterPro 7 KEGG 1 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PROSITE 5 PeptideAtlas 1 Pfam 3 PharmGKB 1 RefSeq 6 SMART 1 SUPFAM 3

Sequence Information:

  • Length: 362
  • Mass: 41155
  • Checksum: 6DD596C803BFD4E7
  • Sequence:
    • MKPLKATATT SQPVLTIQQI ETIFYKIQDI YEIHKEFYDN LCPKVQQWDS QVTMGHLFQK 
LASQLGVYKA FVDNYKVALE TAEKCSQSNN QFQKISEELK VKGPKDSKDS HTSVTMEALL 
YKPIDRVTRS TLVLHDLLKH TPVDHPDYPL LQDALRISQN FLSSINEDID PRRTAVTTPK 
GETRQLVKDG FLVEVSESSR KLRHVFLFTD VLLCAKLKKT SAGKHQQYDC KWYIPLADLV 
FPSPEESEAS PQVHPFPDHE LEDMKMKISA LKSEIQKEVE KRGIEEVGIY RISGVATDIQ 
ALKAVFDANN KDILLMLSDM DINAIAGTLK LYFRELPEPL LTDRLRPCPT PTSSPSSSCW 
NT

Genular Protein ID: 4222051928

Symbol: B7Z683_HUMAN

Name: N/A

UniProtKB Accession Codes:

B7Z683

Database IDs:

ARBA 6 Antibodypedia 1 Bgee 1 BioGRID-ORCS 1 CDD 3 CTD 1 ChiTaRS 1 DNASU 1 EMBL 9 EPD 1 Ensembl 5 GO 5 Gene3D 4 GeneTree 1 GenomeRNAi 1 HGNC 1 InterPro 10 MassIVE 1 MaxQB 1 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PROSITE 8 Pfam 4 Proteomes 2 ProteomicsDB 1 RefSeq 2 SMART 3 SUPFAM 4 UCSC 1 VEuPathDB 1

Citations:

PubMed ID: 16625196

Title: DNA sequence of human chromosome 17 and analysis of rearrangement in the human lineage.

PubMed ID: 16625196

DOI: 10.1038/nature04689

Sequence Information:

  • Length: 641
  • Mass: 73517
  • Checksum: FE84A80387020D68
  • Sequence:
    • MEILLIIRFC CNCTYALLYK PIDRVTRSTL VLHDLLKHTP VDHPDYPLLQ DALRISQNFL 
SSINEDIDPR RTAVTTPKGE TRQLVKDGFL VEVSESSRKL RHVFLFTDVL LCAKLKKTSA 
GKHQQYDCKW YIPLADLVFP SPEESEASPQ VHPFPDHELE DMKMKISALK SEIQKEKANK 
GQSRAIERLK KKMFENEFLL LLNSPTIPFR IHNRNGKSYL FLLSSDYERS EWREAIQKLQ 
KKDLQAFVLS SVELQVLTGS CFKLRTVHNI PVTSNKDDDE SPGLYGFLHV IVHSAKGFKQ 
SANLYCTLEV DSFGYFVSKA KTRVFRDTAE PKWDEEFEIE LEGSQSLRIL CYEKCYDKTK 
VNKDNNEIVD KIMGKGQIQL DPQTVETKNW HTDVIEMNGI KVEFSMKFTS RDMSLKRTPS 
KKQTGVFGVK ISVVTKRERS KVPYIVRQCV EEVEKRGIEE VGIYRISGVA TDIQALKAVF 
DANNKDILLM LSDMDINAIA GTLKLYFREL PEPLLTDRLY PAFMEGIALS DPAAKENCMM 
HLLRSLPDPN LITFLFLLEH LKRVAEKEPI NKMSLHNLAT VFGPTLLRPS EVESKAHLTS 
AADIWSHDVM AQVQVLLYYL QHPPISFAEL KRNTLYFSTD V

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. For the full schema, download it here.