Axin2 | ENSRNOG00000055010 | NCBI 29134

Details for: Axin2

Gene ID: 29134

Symbol: Axin2

Ensembl ID: ENSRNOG00000055010

Description: axin 2

Associated with

Degradation of axin
(R-RNO-4641257)
Deubiquitination
(R-RNO-5688426)
Metabolism of proteins
(R-RNO-392499)
Post-translational protein modification
(R-RNO-597592)
Signaling by wnt
(R-RNO-195721)
Signal transduction
(R-RNO-162582)
Tcf dependent signaling in response to wnt
(R-RNO-201681)
Ub-specific processing proteases
(R-RNO-5689880)
Aortic valve morphogenesis
(GO:0003180)
Beta-catenin binding
(GO:0008013)
Beta-catenin destruction complex
(GO:0030877)
Bone mineralization
(GO:0030282)
Canonical wnt signaling pathway
(GO:0060070)
Cell development
(GO:0048468)
Cell population proliferation
(GO:0008283)
Cellular response to dexamethasone stimulus
(GO:0071549)
Cellular response to organic cyclic compound
(GO:0071407)
Centrosome
(GO:0005813)
Chondrocyte differentiation involved in endochondral bone morphogenesis
(GO:0003413)
Cytoplasm
(GO:0005737)
Dorsal/ventral axis specification
(GO:0009950)
Enzyme binding
(GO:0019899)
I-smad binding
(GO:0070411)
Intramembranous ossification
(GO:0001957)
Maintenance of dna repeat elements
(GO:0043570)
Mitral valve morphogenesis
(GO:0003183)
Molecular adaptor activity
(GO:0060090)
Mrna stabilization
(GO:0048255)
Negative regulation of canonical wnt signaling pathway
(GO:0090090)
Negative regulation of cell population proliferation
(GO:0008285)
Negative regulation of osteoblast differentiation
(GO:0045668)
Negative regulation of osteoblast proliferation
(GO:0033689)
Negative regulation of wnt signaling pathway
(GO:0030178)
Nucleus
(GO:0005634)
Odontogenesis
(GO:0042476)
Osteoblast differentiation
(GO:0001649)
Osteoblast proliferation
(GO:0033687)
Plasma membrane
(GO:0005886)
Positive regulation of epithelial to mesenchymal transition
(GO:0010718)
Positive regulation of fat cell differentiation
(GO:0045600)
Positive regulation of proteasomal ubiquitin-dependent protein catabolic process
(GO:0032436)
Positive regulation of protein kinase activity
(GO:0045860)
Positive regulation of protein phosphorylation
(GO:0001934)
Protein-containing complex
(GO:0032991)
Protein kinase binding
(GO:0019901)
Protein localization
(GO:0008104)
Regulation of centromeric sister chromatid cohesion
(GO:0070602)
Regulation of chondrocyte development
(GO:0061181)
Regulation of extracellular matrix organization
(GO:1903053)
Regulation of mismatch repair
(GO:0032423)
Regulation of wnt signaling pathway
(GO:0030111)
Response to steroid hormone
(GO:0048545)
Secondary heart field specification
(GO:0003139)
Somitogenesis
(GO:0001756)
Stem cell proliferation
(GO:0072089)
Ubiquitin protein ligase binding
(GO:0031625)
Wnt signaling pathway
(GO:0016055)

Other Information

Proteins

Axin-2

Genular Protein ID: 203463679

Symbol: AXIN2_RAT

Name: Axin-2

UniProtKB Accession Codes:

O70240

Database IDs:

Citations:

PubMed ID: 9566905

Title: Axil, a member of the Axin family, interacts with both glycogen synthase kinase 3beta and beta-catenin and inhibits axis formation of Xenopus embryos.

PubMed ID: 9566905

DOI: 10.1128/mcb.18.5.2867

Sequence Information:

Length: 838
Mass: 92948
Checksum: 45B825C13BA07F37
Sequence:

MSSAVLVTLL PDPSSSFRED APRPPVPGEE GETPPCQPSV GKVQSTKPMP VSSNARRNED 
GLGEPEGRAS PDSPLTRWTK SLHSLLGDQD GAYLFRTFLE REKCVDTLDF WFACNGFRQM 
NLKDTKTLRV AKAIYKRYIE NNSVVSKQLK PATKTYIRDG IKKQQIGSVM FDQAQTEIQA 
VMEENAYQVF LTSDIYLEYV RSGGENTAYM SNGGLGSLKV LCGYLPTLNE EEEWTCADLK 
CKLSPTVVGL SSKTLRATAS VRSTETAENG FRSFKRSEPV NPYHVGSGYV FAPATSANDS 
ELSSDALTDD SMSMTDSSVD GIPPYRMGSK KQLQREMHRS VKANGQVSLP HFPRTHRLPK 
EMTPVEPAAF AAELISRLEK LKLELESRHS LEERLQQIRE DEEKEGSEQA LSSRDGAPVQ 
HPLALLPSGS YEEDPQTILD DHLSRVLKTP GCQSPGVGRY SPRSRSPDHH HHHHQQCHAL 
LPTGGKLPPE AACPLLGGKS FLTKQTTKHV HHHYIHHHAV PKTKEEIEAE ATQRVRCLCP 
GGTDYYCYSK CKSHSKPPEP LPGEQFCGSR GGTLPKRNTK GTEPGLALPA REGGMSSAAG 
APQLPGEEGD RSQDVWQWML ESERQSKSKP HSTQSIRKSY PLESARAPPG ERVSRHHLLG 
ASGHPRSAAR AHPFTQDPAM PPLTPPNTLA QLEEACRRLA EVSKPQKQRC CVASQQRDRN 
HPATGQAGPT SFSNPSLASE DHKEPKRLAS VHALQASELI VTYFFCGEEI PYRRMLKAQS 
LTLGHFKEQL SKKGNYRYYF KKASDEFACG AVFEEIWDDE TVLPMYEGRI LGKVERID

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: Axin2

Associated with

Other Information

Axil, a member of the Axin family, interacts with both glycogen synthase kinase 3beta and beta-catenin and inhibits axis formation of Xenopus embryos. PubMed ID: 9566905

Database document:

PubMed ID: 9566905