Hpn | ENSRNOG00000021097 | NCBI 29135

Details for: Hpn

Gene ID: 29135

Symbol: Hpn

Ensembl ID: ENSRNOG00000021097

Description: hepsin

Associated with

Met receptor activation
(R-RNO-6806942)
Signaling by met
(R-RNO-6806834)
Signaling by mst1
(R-RNO-8852405)
Signaling by receptor tyrosine kinases
(R-RNO-9006934)
Signal transduction
(R-RNO-162582)
Apical plasma membrane
(GO:0016324)
Basement membrane disassembly
(GO:0034769)
Cell-cell junction
(GO:0005911)
Cell surface
(GO:0009986)
Cholesterol homeostasis
(GO:0042632)
Cochlea morphogenesis
(GO:0090103)
Cytoplasm
(GO:0005737)
Detection of mechanical stimulus involved in sensory perception of sound
(GO:0050910)
Endoplasmic reticulum membrane
(GO:0005789)
Epithelium development
(GO:0060429)
Membrane
(GO:0016020)
Negative regulation of apoptotic process
(GO:0043066)
Negative regulation of epithelial cell proliferation
(GO:0050680)
Negative regulation of epithelial to mesenchymal transition
(GO:0010719)
Neuronal cell body
(GO:0043025)
Nuclear membrane
(GO:0031965)
Peptidase activity
(GO:0008233)
Pilomotor reflex
(GO:0097195)
Plasma membrane
(GO:0005886)
Positive regulation by host of viral transcription
(GO:0043923)
Positive regulation of cell growth
(GO:0030307)
Positive regulation of gene expression
(GO:0010628)
Positive regulation of hepatocyte proliferation
(GO:2000347)
Positive regulation of plasminogen activation
(GO:0010756)
Positive regulation of thyroid hormone generation
(GO:2000611)
Potassium ion transmembrane transport
(GO:0071805)
Proteolysis
(GO:0006508)
Regulation of cell shape
(GO:0008360)
Response to thyroid hormone
(GO:0097066)
Sensory perception of sound
(GO:0007605)
Serine-type endopeptidase activity
(GO:0004252)
Serine-type exopeptidase activity
(GO:0070008)
Serine-type peptidase activity
(GO:0008236)

Other Information

Proteins

Serine protease hepsin

Genular Protein ID: 3490101489

Symbol: HEPS_RAT

Name: Serine protease hepsin

UniProtKB Accession Codes:

Q05511

Database IDs:

Citations:

PubMed ID: 8318546

Title: Cloning and sequence analysis of rat hepsin, a cell surface serine proteinase.

PubMed ID: 8318546

DOI: 10.1016/0167-4781(93)90137-3

PubMed ID: 17918732

Title: An integrated genetic and functional analysis of the role of type II transmembrane serine proteases (TMPRSSs) in hearing loss.

PubMed ID: 17918732

DOI: 10.1002/humu.20617

Sequence Information:

Length: 416
Mass: 44926
Checksum: E5A9F8FA9550E180
Sequence:

MAKEGGRTAP CCSRPKVAAL TVGTLLFLTG IGAASWAIVT ILLRSDQEPL YQVQLSPGDS 
RLLVLDKTEG TWRLLCSSRS NARVAGLGCE EMGFLRALAH SELDVRTAGA NGTSGFFCVD 
EGGLPLAQRL LDVISVCDCP RGRFLTATCQ DCGRRKLPVD RIVGGQDSSL GRWPWQVSLR 
YDGTHLCGGS LLSGDWVLTA AHCFPERNRV LSRWRVFAGA VARTSPHAVQ LGVQAVIYHG 
GYLPFRDPTI DENSNDIALV HLSSSLPLTE YIQPVCLPAA GQALVDGKVC TVTGWGNTQF 
YGQQAVVLQE ARVPIISNEV CNSPDFYGNQ IKPKMFCAGY PEGGIDACQG DSGGHFVCED 
RISGTSRWRL CGIVSWGTGC ALARKPGVYT KVIDFREWIF QAIKTHSEAT GMVTQP

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.