Jag1 | ENSRNOG00000007443 | NCBI 29146

Details for: Jag1

Gene ID: 29146

Symbol: Jag1

Ensembl ID: ENSRNOG00000007443

Description: jagged canonical Notch ligand 1

Associated with

Notch3 activation and transmission of signal to the nucleus
(R-RNO-9013507)
Rac1 gtpase cycle
(R-RNO-9013149)
Rho gtpase cycle
(R-RNO-9012999)
Signaling by notch
(R-RNO-157118)
Signaling by notch3
(R-RNO-9012852)
Signaling by rho gtpases
(R-RNO-194315)
Signaling by rho gtpases, miro gtpases and rhobtb3
(R-RNO-9716542)
Signal transduction
(R-RNO-162582)
Adherens junction
(GO:0005912)
Animal organ morphogenesis
(GO:0009887)
Animal organ regeneration
(GO:0031100)
Aorta morphogenesis
(GO:0035909)
Apical part of cell
(GO:0045177)
Apical plasma membrane
(GO:0016324)
Blood vessel remodeling
(GO:0001974)
Calcium ion binding
(GO:0005509)
Camera-type eye development
(GO:0043010)
Cardiac neural crest cell development involved in outflow tract morphogenesis
(GO:0061309)
Cardiac right ventricle morphogenesis
(GO:0003215)
Cardiac septum morphogenesis
(GO:0060411)
Cell fate determination
(GO:0001709)
Ciliary body morphogenesis
(GO:0061073)
Distal tubule development
(GO:0072017)
Endocardial cushion cell development
(GO:0061444)
Inhibition of neuroepithelial cell differentiation
(GO:0002085)
Inner ear auditory receptor cell differentiation
(GO:0042491)
Inner ear development
(GO:0048839)
Loop of henle development
(GO:0072070)
Membrane
(GO:0016020)
Molecular adaptor activity
(GO:0060090)
Morphogenesis of an epithelial sheet
(GO:0002011)
Negative regulation of cell-cell adhesion
(GO:0022408)
Negative regulation of cell-matrix adhesion
(GO:0001953)
Negative regulation of cell differentiation
(GO:0045596)
Negative regulation of cell migration
(GO:0030336)
Negative regulation of endothelial cell differentiation
(GO:0045602)
Negative regulation of fat cell differentiation
(GO:0045599)
Negative regulation of neuron differentiation
(GO:0045665)
Negative regulation of stem cell differentiation
(GO:2000737)
Nephron development
(GO:0072006)
Nervous system development
(GO:0007399)
Neuroendocrine cell differentiation
(GO:0061101)
Neuronal stem cell population maintenance
(GO:0097150)
Neuron differentiation
(GO:0030182)
Notch binding
(GO:0005112)
Notch signaling pathway
(GO:0007219)
Phospholipid binding
(GO:0005543)
Plasma membrane
(GO:0005886)
Podocyte development
(GO:0072015)
Positive regulation of cardiac epithelial to mesenchymal transition
(GO:0062043)
Positive regulation of gene expression
(GO:0010628)
Positive regulation of myeloid cell differentiation
(GO:0045639)
Positive regulation of notch signaling pathway
(GO:0045747)
Positive regulation of osteoblast differentiation
(GO:0045669)
Positive regulation of transcription by rna polymerase ii
(GO:0045944)
Protein binding
(GO:0005515)
Pulmonary artery morphogenesis
(GO:0061156)
Pulmonary valve morphogenesis
(GO:0003184)
Receptor ligand activity
(GO:0048018)
Regulation of cell population proliferation
(GO:0042127)
Regulation of epithelial cell proliferation
(GO:0050678)
Regulation of reproductive process
(GO:2000241)
Response to muramyl dipeptide
(GO:0032495)
T cell mediated immunity
(GO:0002456)
Wound healing
(GO:0042060)

Other Information

Proteins

Protein jagged-1

Genular Protein ID: 1315867146

Symbol: JAG1_RAT

Name: Protein jagged-1

UniProtKB Accession Codes:

Q63722 P70640

Database IDs:

Citations:

PubMed ID: 7697721

Title: Jagged: a mammalian ligand that activates Notch1.

PubMed ID: 7697721

DOI: 10.1016/0092-8674(95)90294-5

PubMed ID: 28089369

Title: Deciphering the fringe-mediated notch code: identification of activating and inhibiting sites allowing discrimination between ligands.

PubMed ID: 28089369

DOI: 10.1016/j.devcel.2016.12.013

Sequence Information:

Length: 1219
Mass: 134326
Checksum: 65D4CFC238A0E204
Sequence:

MRSPRTRGRP GRPLSLLLAL LCALRAKVCG ASGQFELEIL SMQNVNGELQ NGNCCGGARN 
PGDRKCTRDE CDTYFKVCLK EYQSRVTAGG PCSFGSGSTP VIGGNTFNLK ASRGNDRNRI 
VLPFSFAWPR SYTLLVEAWD SSNDTIQPDS IIEKASHSGM INPSRQWQTL KQNTGIAHFE 
YQIRVTCDDH YYGFGCNKFC RPRDDFFGHY ACDQNGNKTC MEGWMGPECN KAICRQGCSP 
KHGSCKLPGD CRCQYGWQGL YCDKCIPHPG CVHGTCNEPW QCLCETNWGG QLCDKDLNYC 
GTHQPCLNRG TCSNTGPDKY QCSCPEGYSG PNCEIAEHAC LSDPCHNRGS CKETSSGFEC 
ECSPGWTGPT CSTNIDDCSP NNCSHGGTCQ DLVNGFKCVC PPQWTGKTCQ LDANECEAKP 
CVNARSCKNL IASYYCDCLP GWMGQNCDIN INDCLGQCQN DASCRDLVNG YRCICPPGYA 
GDHCERDIDE CASNPCLNGG HCQNEINRFQ CLCPTGFSGN LCQLDIDYCE PNPCQNGAQC 
YNRASDYFCK CPEDYEGKNC SHLKDHCRTT PCEVIDSCTV AMASNDTPEG VRYISSNVCG 
PHGKCKSESG GKFTCDCNKG FTGTYCHENI NDCEGNPCTN GGTCIDGVNS YKCICSDGWE 
GAHCENNIND CSQNPCHYGG TCRDLVNDFY CDCKNGWKGK TCHSRDSQCD EATCNNGGTC 
YDEVDTFKCM CPGGWEGTTC NIARNSSCLP NPCHNGGTCV VNGDSFTCVC KEGWEGPICT 
QNTNDCSPHP CYNSGTCVDG DNWYRCECAP GFAGPDCRIN INECQSSPCA FGATCVDEIN 
GYQCICPPGH SGAKCHEVSG RSCITMGRVI LDGAKWDDDC NTCQCLNGRV ACSKVWCGPR 
PCRLHKGHGE CPNGQSCIPV LDDQCFVRPC TGAGECRSSS LQPVKTKCTS DSYYQDNCAN 
ITFTFNKEMM SPGLTTEHIC SELRNLNILK NVSAEYSIYI ACEPSLSANN EIHVAISAED 
IRDDGNPVKE ITDKIIDLVS KRDGNSSLIA AVAEVRVQRR PLKNRTDFLV PLLSSVLTVA 
WVCCLVTAFY WCVRKRRRKP SSHTHSAPED NTTNNVREQL NQIKNPIEKH GANTVPIKDY 
ENKNSKMSKI RTHNSEVEED DMDKHQQKVR FAKQPVYTLV DREEKVPQRT PTKHPNWTNK 
QDNRDLESAQ SLNRMEYIV

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.