Details for: Mstn

Gene ID: 29152

Symbol: Mstn

Ensembl ID: ENSRNOG00000021294

Description: myostatin

Associated with

  • Cellular response to dexamethasone stimulus
    (GO:0071549)
  • Cellular response to hypoxia
    (GO:0071456)
  • Cytokine activity
    (GO:0005125)
  • Extracellular space
    (GO:0005615)
  • Growth factor activity
    (GO:0008083)
  • Heparin binding
    (GO:0008201)
  • Identical protein binding
    (GO:0042802)
  • Muscle cell cellular homeostasis
    (GO:0046716)
  • Myoblast migration involved in skeletal muscle regeneration
    (GO:0014839)
  • Negative regulation of insulin receptor signaling pathway
    (GO:0046627)
  • Negative regulation of muscle hypertrophy
    (GO:0014741)
  • Negative regulation of myoblast differentiation
    (GO:0045662)
  • Negative regulation of myoblast proliferation
    (GO:2000818)
  • Negative regulation of phosphatidylinositol 3-kinase/protein kinase b signal transduction
    (GO:0051898)
  • Negative regulation of satellite cell differentiation
    (GO:1902725)
  • Negative regulation of skeletal muscle satellite cell proliferation
    (GO:1902723)
  • Negative regulation of skeletal muscle tissue growth
    (GO:0048632)
  • Ovulation cycle process
    (GO:0022602)
  • Positive regulation of dna-templated transcription
    (GO:0045893)
  • Positive regulation of lamellipodium assembly
    (GO:0010592)
  • Positive regulation of macrophage chemotaxis
    (GO:0010759)
  • Protein homodimerization activity
    (GO:0042803)
  • Response to electrical stimulus
    (GO:0051602)
  • Response to estrogen
    (GO:0043627)
  • Response to ethanol
    (GO:0045471)
  • Response to glucocorticoid
    (GO:0051384)
  • Response to gravity
    (GO:0009629)
  • Response to muscle activity
    (GO:0014850)
  • Response to testosterone
    (GO:0033574)
  • Signaling receptor binding
    (GO:0005102)
  • Skeletal muscle atrophy
    (GO:0014732)
  • Skeletal muscle satellite cell differentiation
    (GO:0014816)
  • Skeletal muscle tissue regeneration
    (GO:0043403)
  • Transforming growth factor beta receptor signaling pathway
    (GO:0007179)

Other Information

Genular Protein ID: 1883221262

Symbol: GDF8_RAT

Name: Growth/differentiation factor 8

UniProtKB Accession Codes:

O35312

Database IDs:

ABCD 1 AGR 1 AlphaFoldDB 1 Bgee 1 CDD 1 CTD 1 EMBL 1 Ensembl 4 GO 34 Gene3D 2 GeneTree 1 Genevisible 1 GlyCosmos 1 GlyGen 1 HOGENOM 1 InParanoid 1 InterPro 5 KEGG 1 NCBI Taxonomy 1 OMA 1 OrthoDB 1 PANTHER 2 PRO 1 PROSITE 2 PaxDb 1 Pfam 2 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 RGD 1 RefSeq 1 SMART 1 SMR 1 STRING 1 SUPFAM 1 TreeFam 1 UCSC 1 UniProtKB 2 eggNOG 1

Citations:

PubMed ID: 9356471

Title: Double muscling in cattle due to mutations in the myostatin gene.

PubMed ID: 9356471

DOI: 10.1073/pnas.94.23.12457

Sequence Information:

  • Length: 376
  • Mass: 42829
  • Checksum: 933043D8C8C3294B
  • Sequence:
    • MIQKPQMYVY IYLFVLIAAG PVDLNEDSER EANVEKEGLC NACAWRQNTR YSRIEAIKIQ 
ILSKLRLETA PNISKDAIRQ LLPRAPPLRE LIDQYDVQRD DSSDGSLEDD DYHATTETII 
TMPTESDFLM QADGKPKCCF FKFSSKIQYN KVVKAQLWIY LRAVKTPTTV FVQILRLIKP 
MKDGTRYTGI RSLKLDMSPG TGIWQSIDVK TVLQNWLKQP ESNLGIEIKA LDENGHDLAV 
TFPGPGEDGL NPFLEVKVTD TPKRSRRDFG LDCDEHSTES RCCRYPLTVD FEAFGWDWII 
APKRYKANYC SGECEFVFLQ KYPHTHLVHQ ANPRGSAGPC CTPTKMSPIN MLYFNGKEQI 
IYGKIPAMVV DRCGCS

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.