Details for: Capn1

Gene ID: 29153

Symbol: Capn1

Ensembl ID: ENSRNOG00000020935

Description: calpain 1

Associated with

Other Information

Genular Protein ID: 1490713460

Symbol: CAN1_RAT

Name: Calcium-activated neutral proteinase 1

UniProtKB Accession Codes:

Database IDs:

Citations:

PubMed ID: 8950173

Title: Primary sequences of rat mu-calpain large and small subunits are, respectively, moderately and highly similar to those of human.

PubMed ID: 8950173

DOI: 10.1016/s0167-4781(96)00135-2

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 11893336

Title: A Ca(2+) switch aligns the active site of calpain.

PubMed ID: 11893336

DOI: 10.1016/s0092-8674(02)00659-1

PubMed ID: 14656436

Title: Crystal structure of a micro-like calpain reveals a partially activated conformation with low Ca2+ requirement.

PubMed ID: 14656436

DOI: 10.1016/j.str.2003.11.007

PubMed ID: 15491615

Title: Crystal structures of calpain-E64 and -leupeptin inhibitor complexes reveal mobile loops gating the active site.

PubMed ID: 15491615

DOI: 10.1016/j.jmb.2004.09.016

Sequence Information:

  • Length: 713
  • Mass: 82119
  • Checksum: 6E664600B0EFAEBB
  • Sequence:
  • MAEELITPVY CTGVSAQVQK QRDKELGLGR HENAIKYLGQ DYENLRARCL QNGVLFQDDA 
    FPPVSHSLGF KELGPNSSKT YGIKWKRPTE LLSNPQFIVD GATRTDICQG ALGDCWLLAA 
    IASLTLNETI LHRVVPYGQS FQEGYAGIFH FQLWQFGEWV DVVVDDLLPT KDGKLVFVHS 
    AQGNEFWSAL LEKAYAKVNG SYEALSGGCT SEAFEDFTGG VTEWYDLQKA PSDLYQIILK 
    ALERGSLLGC SINISDIRDL EAITFKNLVR GHAYSVTDAK QVTYQGQRVN LIRMRNPWGE 
    VEWKGPWSDN SYEWNKVDPY EREQLRVKME DGEFWMSFRD FIREFTKLEI CNLTPDALKS 
    RTLRNWNTTF YEGTWRRGST AGGCRNYPAT FWVNPQFKIR LEEVDDADDY DSRESGCSFL 
    LALMQKHRRR ERRFGRDMET IGFAVYQVPR ELAGQPVHLK RDFFLANASR AQSEHFINLR 
    EVSNRIRLPP GEYIVVPSTF EPNKEGDFLL RFFSEKKAGT QELDDQIQAN LPDEKVLSEE 
    EIDDNFKTLF SKLAGDDMEI SVKELQTILN RIISKHKDLR TNGFSLESCR SMVNLMDRDG 
    NGKLGLVEFN ILWNRIRNYL TIFRKFDLDK SGSMSAYEMR MAIEAAGFKL NKKLHELIIT 
    RYSEPDLAVD FDNFVCCLVR LETMFRFFKI LDTDLDGVVT FDLFKWLQLT MFA

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.