Details for: Capn2

Gene ID: 29154

Symbol: Capn2

Ensembl ID: ENSRNOG00000034015

Description: calpain 2

Associated with

Other Information

Genular Protein ID: 1957066514

Symbol: CAN2_RAT

Name: Calpain-2 catalytic subunit

UniProtKB Accession Codes:

Database IDs:

Citations:

PubMed ID: 8218419

Title: Molecular cloning and bacterial expression of cDNA for rat calpain II 80 kDa subunit.

PubMed ID: 8218419

DOI: 10.1016/0167-4781(93)90040-k

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 11342050

Title: Ca(2+)-induced structural changes in rat m-calpain revealed by partial proteolysis.

PubMed ID: 11342050

DOI: 10.1016/s0167-4838(00)00286-7

PubMed ID: 11102442

Title: Calpain mutants with increased Ca2+ sensitivity and implications for the role of the C(2)-like domain.

PubMed ID: 11102442

DOI: 10.1074/jbc.m007352200

PubMed ID: 7635186

Title: Active site residues in m-calpain: identification by site-directed mutagenesis.

PubMed ID: 7635186

DOI: 10.1016/0014-5793(95)00691-2

PubMed ID: 10601010

Title: Crystal structure of calpain reveals the structural basis for Ca(2+)-dependent protease activity and a novel mode of enzyme activation.

PubMed ID: 10601010

DOI: 10.1093/emboj/18.24.6880

PubMed ID: 19020622

Title: Concerted multi-pronged attack by calpastatin to occlude the catalytic cleft of heterodimeric calpains.

PubMed ID: 19020622

DOI: 10.1038/nature07353

PubMed ID: 19020623

Title: Calcium-bound structure of calpain and its mechanism of inhibition by calpastatin.

PubMed ID: 19020623

DOI: 10.1038/nature07451

Sequence Information:

  • Length: 700
  • Mass: 79919
  • Checksum: 296B0DC3BEEF5B90
  • Sequence:
  • MAGIAMKLAK DREAAEGLGS HERAIKYLNQ DYETLRNECL EAGALFQDPS FPALPSSLGF 
    KELGPYSSKT RGIEWKRPTE ICADPQFIIG GATRTDICQG ALGDCWLLAA IASLTLNEEI 
    LARVVPLDQS FQENYAGIFH FQFWQYGEWV EVVVDDRLPT KDGELLFVHS AEGSEFWSAL 
    LEKAYAKING CYEALSGGAT TEGFEDFTGG IAEWYELRKP PPNLFKIIQK ALEKGSLLGC 
    SIDITSAADS EAVTYQKLVK GHAYSVTGAE EVESSGSLQK LIRIRNPWGQ VEWTGKWNDN 
    CPSWNTVDPE VRANLTERQE DGEFWMSFSD FLRHYSRLEI CNLTPDTLTC DSYKKWKLTK 
    MDGNWRRGST AGGCRNYPNT FWMNPQYLIK LEEEDEDDED GERGCTFLVG LIQKHRRRQR 
    KMGEDMHTIG FGIYEVPEEL TGQTNIHLSK NFFLTTRARE RSDTFINLRE VLNRFKLPPG 
    EYVLVPSTFE PHKNGDFCIR VFSEKKADYQ TVDDEIEANI EEIEANEEDI GDGFRRLFAQ 
    LAGEDAEISA FELQTILRRV LAKREDIKSD GFSIETCKIM VDMLDEDGSG KLGLKEFYIL 
    WTKIQKYQKI YREIDVDRSG TMNSYEMRKA LEEAGFKLPC QLHQVIVARF ADDELIIDFD 
    NFVRCLVRLE ILFKIFKQLD PENTGTIQLD LISWLSFSVL

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.