Details for: Capns1

Gene ID: 29156

Symbol: Capns1

Ensembl ID: ENSRNOG00000067065

Description: calpain, small subunit 1

Associated with

Other Information

Genular Protein ID: 3253864929

Symbol: CPNS1_RAT

Name: Calpain small subunit 1

UniProtKB Accession Codes:

Q64537 P97572 Q4V795

Database IDs:

AGR 1 AlphaFoldDB 1 BRENDA 1 CDD 1 CTD 1 ChEBI 16 DIP 1 EMBL 3 Ensembl 3 EvolutionaryTrace 1 GO 8 Gene3D 1 InParanoid 1 IntAct 1 InterPro 3 KEGG 1 MINT 1 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PDB 15 PDBsum 8 PIR 1 PRO 1 PROSITE 2 PROSITE-ProRule 1 PaxDb 1 Pfam 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 RGD 1 Reactome 1 RefSeq 2 SMR 1 STRING 1 SUPFAM 1 UCSC 1 UniProtKB 2 eggNOG 1 iPTMnet 1 jPOST 1

Citations:

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 8950173

Title: Primary sequences of rat mu-calpain large and small subunits are, respectively, moderately and highly similar to those of human.

PubMed ID: 8950173

DOI: 10.1016/s0167-4781(96)00135-2

PubMed ID: 7982961

Title: Active recombinant rat calpain II. Bacterially produced large and small subunits associate both in vivo and in vitro.

PubMed ID: 7982961

DOI: 10.1016/s0021-9258(18)43835-5

PubMed ID: 9228945

Title: Structure of a calpain Ca(2+)-binding domain reveals a novel EF-hand and Ca(2+)-induced conformational changes.

PubMed ID: 9228945

DOI: 10.1038/nsb0797-532

PubMed ID: 14579356

Title: A second binding site revealed by C-terminal truncation of calpain small subunit, a penta-EF-hand protein.

PubMed ID: 14579356

DOI: 10.1002/prot.10453

PubMed ID: 15476820

Title: Activation of calpain by Ca2+: roles of the large subunit N-terminal and domain III-IV linker peptides.

PubMed ID: 15476820

DOI: 10.1016/j.jmb.2004.08.073

PubMed ID: 19020623

Title: Calcium-bound structure of calpain and its mechanism of inhibition by calpastatin.

PubMed ID: 19020623

DOI: 10.1038/nature07451

PubMed ID: 19020622

Title: Concerted multi-pronged attack by calpastatin to occlude the catalytic cleft of heterodimeric calpains.

PubMed ID: 19020622

DOI: 10.1038/nature07353

Sequence Information:

  • Length: 270
  • Mass: 28570
  • Checksum: 63609614CD4D3EB7
  • Sequence:
    • MFLVNSFLKG GGGGGGGGGL GGGLGNVLGG LISGAAGGGG GGGGGGGMGL GGGGGGGGTA 
MRILGGVISA ISEAAAQYNP EPPPPRSHYS NIEANESEEE RQFRKLFVQL AGDDMEVSAT 
ELMNILNKVV TRHPDLKTDG FGIDTCRSMV AVMDSDTTGK LGFEEFKYLW NNIKKWQGIY 
KRFDTDRSGT IGSNELPGAF EAAGFHLNQH IYSMIIRRYS DETGNMDFDN FISCLVRLDA 
MFRAFRSLDK NGTGQIQVNI QEWLQLTMYS

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.