Snca | ENSRNOG00000008656 | NCBI 29219

Details for: Snca

Gene ID: 29219

Symbol: Snca

Ensembl ID: ENSRNOG00000008656

Description: synuclein alpha

Associated with

Antiviral mechanism by ifn-stimulated genes
(R-RNO-1169410)
Cytokine signaling in immune system
(R-RNO-1280215)
Immune system
(R-RNO-168256)
Interferon signaling
(R-RNO-913531)
Pkr-mediated signaling
(R-RNO-9833482)
Actin binding
(GO:0003779)
Adult locomotory behavior
(GO:0008344)
Alpha-tubulin binding
(GO:0043014)
Arachidonic acid binding
(GO:0050544)
Behavioral response to cocaine
(GO:0048148)
Beta-tubulin binding
(GO:0048487)
Calcium ion binding
(GO:0005509)
Calcium ion homeostasis
(GO:0055074)
Cellular response to fibroblast growth factor stimulus
(GO:0044344)
Cellular response to oxidative stress
(GO:0034599)
Chemical synaptic transmission
(GO:0007268)
Copper ion binding
(GO:0005507)
Cuprous ion binding
(GO:1903136)
Cysteine-type endopeptidase inhibitor activity involved in apoptotic process
(GO:0043027)
Dopamine biosynthetic process
(GO:0042416)
Dopamine metabolic process
(GO:0042417)
Dynein complex binding
(GO:0070840)
Enzyme binding
(GO:0019899)
Fatty acid binding
(GO:0005504)
Fatty acid metabolic process
(GO:0006631)
Ferrous iron binding
(GO:0008198)
Histone binding
(GO:0042393)
Hsp70 protein binding
(GO:0030544)
Identical protein binding
(GO:0042802)
Kinesin binding
(GO:0019894)
Lipid binding
(GO:0008289)
Localization
(GO:0051179)
Magnesium ion binding
(GO:0000287)
Microglial cell activation
(GO:0001774)
Microtubule binding
(GO:0008017)
Mitochondrial atp synthesis coupled electron transport
(GO:0042775)
Mitochondrial membrane organization
(GO:0007006)
Molecular adaptor activity
(GO:0060090)
Negative regulation of apoptotic process
(GO:0043066)
Negative regulation of dopamine metabolic process
(GO:0045963)
Negative regulation of dopamine uptake involved in synaptic transmission
(GO:0051585)
Negative regulation of exocytosis
(GO:0045920)
Negative regulation of microtubule polymerization
(GO:0031115)
Negative regulation of neuron apoptotic process
(GO:0043524)
Negative regulation of norepinephrine uptake
(GO:0051622)
Negative regulation of platelet-derived growth factor receptor signaling pathway
(GO:0010642)
Negative regulation of protein phosphorylation
(GO:0001933)
Negative regulation of serotonin uptake
(GO:0051612)
Neuron apoptotic process
(GO:0051402)
Neurotransmitter secretion
(GO:0007269)
Neutral lipid metabolic process
(GO:0006638)
Oxidoreductase activity
(GO:0016491)
Phospholipase binding
(GO:0043274)
Phospholipase d inhibitor activity
(GO:0060961)
Phospholipid binding
(GO:0005543)
Phospholipid metabolic process
(GO:0006644)
Phosphoprotein binding
(GO:0051219)
Positive regulation of endocytosis
(GO:0045807)
Positive regulation of exocytosis
(GO:0045921)
Positive regulation of inflammatory response
(GO:0050729)
Positive regulation of neurotransmitter secretion
(GO:0001956)
Positive regulation of peptidyl-serine phosphorylation
(GO:0033138)
Positive regulation of receptor recycling
(GO:0001921)
Positive regulation of release of sequestered calcium ion into cytosol
(GO:0051281)
Positive regulation of snare complex assembly
(GO:0035543)
Positive regulation of synaptic transmission
(GO:0050806)
Protein binding
(GO:0005515)
Protein complex oligomerization
(GO:0051259)
Protein destabilization
(GO:0031648)
Protein domain specific binding
(GO:0019904)
Protein tetramerization
(GO:0051262)
Receptor internalization
(GO:0031623)
Regulation of acyl-coa biosynthetic process
(GO:0050812)
Regulation of dopamine secretion
(GO:0014059)
Regulation of glutamate secretion
(GO:0014048)
Regulation of locomotion
(GO:0040012)
Regulation of long-term neuronal synaptic plasticity
(GO:0048169)
Regulation of macrophage activation
(GO:0043030)
Regulation of neuronal synaptic plasticity
(GO:0048168)
Regulation of neuron apoptotic process
(GO:0043523)
Regulation of neurotransmitter secretion
(GO:0046928)
Regulation of norepinephrine uptake
(GO:0051621)
Response to cocaine
(GO:0042220)
Response to iron(ii) ion
(GO:0010040)
Response to lipopolysaccharide
(GO:0032496)
Response to magnesium ion
(GO:0032026)
Response to type ii interferon
(GO:0034341)
Response to xenobiotic stimulus
(GO:0009410)
Snare binding
(GO:0000149)
Snare complex assembly
(GO:0035493)
Synapse organization
(GO:0050808)
Synaptic transmission, dopaminergic
(GO:0001963)
Synaptic vesicle endocytosis
(GO:0048488)
Synaptic vesicle exocytosis
(GO:0016079)
Synaptic vesicle priming
(GO:0016082)
Synaptic vesicle transport
(GO:0048489)
Tau protein binding
(GO:0048156)
Zinc ion binding
(GO:0008270)

Other Information

Proteins

Alpha-synuclein
A6KF07_RAT

Genular Protein ID: 3317756448

Symbol: SYUA_RAT

Name: Alpha-synuclein

UniProtKB Accession Codes:

P37377 P37378 Q53YM9

Database IDs:

Citations:

PubMed ID: 1661825

Title: The rat brain synucleins; family of proteins transiently associated with neuronal membrane.

PubMed ID: 1661825

DOI: 10.1016/0169-328x(91)90043-w

PubMed ID: 3411354

Title: Synuclein: a neuron-specific protein localized to the nucleus and presynaptic nerve terminal.

PubMed ID: 3411354

DOI: 10.1523/jneurosci.08-08-02804.1988

PubMed ID: 10582622

Title: Increased expression of rat synuclein in the substantia nigra pars compacta identified by mRNA differential display in a model of developmental target injury.

PubMed ID: 10582622

DOI: 10.1046/j.1471-4159.1999.0732586.x

PubMed ID: 12665621

Title: Alpha-synuclein maps to a quantitative trait locus for alcohol preference and is differentially expressed in alcohol-preferring and - nonpreferring rats.

PubMed ID: 12665621

DOI: 10.1073/pnas.0737182100

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 12408865

Title: The UCH-L1 gene encodes two opposing enzymatic activities that affect alpha-synuclein degradation and Parkinson's disease susceptibility.

PubMed ID: 12408865

DOI: 10.1016/s0092-8674(02)01012-7

PubMed ID: 22673903

Title: Quantitative maps of protein phosphorylation sites across 14 different rat organs and tissues.

PubMed ID: 22673903

DOI: 10.1038/ncomms1871

Sequence Information:

Length: 140
Mass: 14515
Checksum: 1FFD19CD3B9E636C
Sequence:

MDVFMKGLSK AKEGVVAAAE KTKQGVAEAA GKTKEGVLYV GSKTKEGVVH GVTTVAEKTK 
EQVTNVGGAV VTGVTAVAQK TVEGAGNIAA ATGFVKKDQM GKGEEGYPQE GILEDMPVDP 
SSEAYEMPSE EGYQDYEPEA

Genular Protein ID: 2587689083

Symbol: A6KF07_RAT

Name: N/A

UniProtKB Accession Codes:

A6KF07

Database IDs:

Sequence Information:

Length: 149
Mass: 15755
Checksum: 972D3414A95EA9DE
Sequence:

MDVFMKGLSK AKEGVVAAAE KTKQGVAEAA GKTKEGVLYV GSKTKEGVVH GVTTVAEKTK 
EQVTNVGGAV VTGVTAVAQK TVEGAGNIAA ATGFVKKDQM GKGYPMGECT NHPPRLIALR 
VKSRYREHSW RPRKQLSLAC VVMDPFLPT

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: Snca

Associated with

Other Information

The rat brain synucleins; family of proteins transiently associated with neuronal membrane. PubMed ID: 1661825

Synuclein: a neuron-specific protein localized to the nucleus and presynaptic nerve terminal. PubMed ID: 3411354

Increased expression of rat synuclein in the substantia nigra pars compacta identified by mRNA differential display in a model of developmental target injury. PubMed ID: 10582622

Alpha-synuclein maps to a quantitative trait locus for alcohol preference and is differentially expressed in alcohol-preferring and - nonpreferring rats. PubMed ID: 12665621

The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). PubMed ID: 15489334

The UCH-L1 gene encodes two opposing enzymatic activities that affect alpha-synuclein degradation and Parkinson's disease susceptibility. PubMed ID: 12408865

Quantitative maps of protein phosphorylation sites across 14 different rat organs and tissues. PubMed ID: 22673903