Drd3 | ENSRNOG00000060806 | NCBI 29238

Details for: Drd3

Gene ID: 29238

Symbol: Drd3

Ensembl ID: ENSRNOG00000060806

Description: dopamine receptor D3

Associated with

Amine ligand-binding receptors
(R-RNO-375280)
Class a/1 (rhodopsin-like receptors)
(R-RNO-373076)
Dopamine receptors
(R-RNO-390651)
G alpha (i) signalling events
(R-RNO-418594)
Gpcr downstream signalling
(R-RNO-388396)
Gpcr ligand binding
(R-RNO-500792)
Signaling by gpcr
(R-RNO-372790)
Signal transduction
(R-RNO-162582)
Acid secretion
(GO:0046717)
Adenylate cyclase-activating adrenergic receptor signaling pathway
(GO:0071880)
Adenylate cyclase-activating dopamine receptor signaling pathway
(GO:0007191)
Adenylate cyclase-inhibiting dopamine receptor signaling pathway
(GO:0007195)
Apical part of cell
(GO:0045177)
Arachidonic acid secretion
(GO:0050482)
Autophagy
(GO:0006914)
Behavioral response to cocaine
(GO:0048148)
Cell projection
(GO:0042995)
Circadian regulation of gene expression
(GO:0032922)
D1 dopamine receptor binding
(GO:0031748)
Dopamine neurotransmitter receptor activity
(GO:0004952)
Dopamine neurotransmitter receptor activity, coupled via gi/go
(GO:0001591)
Dopamine receptor signaling pathway
(GO:0007212)
Dopaminergic synapse
(GO:0098691)
Endocytic vesicle
(GO:0030139)
Gaba-ergic synapse
(GO:0098982)
Glutamatergic synapse
(GO:0098978)
G protein-coupled receptor activity
(GO:0004930)
G protein-coupled receptor internalization
(GO:0002031)
G protein-coupled receptor signaling pathway
(GO:0007186)
Intracellular calcium ion homeostasis
(GO:0006874)
Locomotory behavior
(GO:0007626)
Membrane
(GO:0016020)
Musculoskeletal movement, spinal reflex action
(GO:0050883)
Negative regulation of adenylate cyclase activity
(GO:0007194)
Negative regulation of apoptotic process
(GO:0043066)
Negative regulation of blood pressure
(GO:0045776)
Negative regulation of cytosolic calcium ion concentration
(GO:0051481)
Negative regulation of dopamine receptor signaling pathway
(GO:0060160)
Negative regulation of oligodendrocyte differentiation
(GO:0048715)
Negative regulation of phosphatidylinositol 3-kinase/protein kinase b signal transduction
(GO:0051898)
Negative regulation of protein secretion
(GO:0050709)
Negative regulation of synaptic transmission, glutamatergic
(GO:0051967)
Negative regulation of transcription by rna polymerase ii
(GO:0000122)
Negative regulation of voltage-gated calcium channel activity
(GO:1901386)
Oligodendrocyte differentiation
(GO:0048709)
Phosphatidylinositol 3-kinase/protein kinase b signal transduction
(GO:0043491)
Phospholipase c-activating dopamine receptor signaling pathway
(GO:0060158)
Plasma membrane
(GO:0005886)
Positive regulation of cell population proliferation
(GO:0008284)
Positive regulation of cytokinesis
(GO:0032467)
Positive regulation of dopamine receptor signaling pathway
(GO:0060161)
Positive regulation of mitotic nuclear division
(GO:0045840)
Positive regulation of transcription by rna polymerase ii
(GO:0045944)
Postsynaptic density membrane
(GO:0098839)
Prepulse inhibition
(GO:0060134)
Protein binding
(GO:0005515)
Protein domain specific binding
(GO:0019904)
Regulation of biological quality
(GO:0065008)
Regulation of blood volume by renin-angiotensin
(GO:0002016)
Regulation of circadian sleep/wake cycle, sleep
(GO:0045187)
Regulation of dopamine secretion
(GO:0014059)
Regulation of lipid metabolic process
(GO:0019216)
Regulation of locomotion
(GO:0040012)
Regulation of locomotion involved in locomotory behavior
(GO:0090325)
Regulation of multicellular organism growth
(GO:0040014)
Regulation of neurotransmitter uptake
(GO:0051580)
Regulation of postsynaptic neurotransmitter receptor internalization
(GO:0099149)
Regulation of potassium ion transport
(GO:0043266)
Response to amphetamine
(GO:0001975)
Response to cocaine
(GO:0042220)
Response to ethanol
(GO:0045471)
Response to histamine
(GO:0034776)
Response to morphine
(GO:0043278)
Response to xenobiotic stimulus
(GO:0009410)
Synaptic transmission, dopaminergic
(GO:0001963)
Visual learning
(GO:0008542)

Other Information

Proteins

D(3) dopamine receptor

Genular Protein ID: 3561909632

Symbol: DRD3_RAT

Name: D(3) dopamine receptor

UniProtKB Accession Codes:

P19020 P70647

Database IDs:

Citations:

PubMed ID: 1975644

Title: Molecular cloning and characterization of a novel dopamine receptor (D3) as a target for neuroleptics.

PubMed ID: 1975644

DOI: 10.1038/347146a0

PubMed ID: 2039532

Title: Shorter variants of the D3 dopamine receptor produced through various patterns of alternative splicing.

PubMed ID: 2039532

DOI: 10.1016/0006-291x(91)90469-n

PubMed ID: 8333859

Title: Characterization of a novel exon within the D3 receptor gene giving rise to an mRNA isoform expressed in rat brain.

PubMed ID: 8333859

DOI: 10.1006/bbrc.1993.1842

PubMed ID: 14499480

Title: CLIC6, a member of the intracellular chloride channel family, interacts with dopamine D(2)-like receptors.

PubMed ID: 14499480

DOI: 10.1016/s0169-328x(03)00283-3

PubMed ID: 1358063

Title: Molecular modelling of D2-like dopamine receptors.

PubMed ID: 1358063

DOI: 10.1042/bj2870277

Sequence Information:

Length: 446
Mass: 49516
Checksum: 180E36AFF217E9DB
Sequence:

MAPLSQISTH LNSTCGAENS TGVNRARPHA YYALSYCALI LAIIFGNGLV CAAVLRERAL 
QTTTNYLVVS LAVADLLVAT LVMPWVVYLE VTGGVWNFSR ICCDVFVTLD VMMCTASILN 
LCAISIDRYT AVVMPVHYQH GTGQSSCRRV ALMITAVWVL AFAVSCPLLF GFNTTGDPSI 
CSISNPDFVI YSSVVSFYVP FGVTVLVYAR IYIVLRQRQR KRILTRQNSQ CISIRPGFPQ 
QSSCLRLHPI RQFSIRARFL SDATGQMEHI EDKQYPQKCQ DPLLSHLQPP SPGQTHGGLK 
RYYSICQDTA LRHPSLEGGA GMSPVERTRN SLSPTMAPKL SLEVRKLSNG RLSTSLRLGP 
LQPRGVPLRE KKATQMVVIV LGAFIVCWLP FFLTHVLNTH CQACHVSPEL YRATTWLGYV 
NSALNPVIYT TFNVEFRKAF LKILSC

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: Drd3

Associated with

Other Information

Molecular cloning and characterization of a novel dopamine receptor (D3) as a target for neuroleptics. PubMed ID: 1975644

Shorter variants of the D3 dopamine receptor produced through various patterns of alternative splicing. PubMed ID: 2039532

Characterization of a novel exon within the D3 receptor gene giving rise to an mRNA isoform expressed in rat brain. PubMed ID: 8333859