Details for: Gch1

Gene ID: 29244

Symbol: Gch1

Ensembl ID: ENSRNOG00000011039

Description: GTP cyclohydrolase 1

Associated with

Other Information

Genular Protein ID: 4077256204

Symbol: GCH1_RAT

Name: GTP cyclohydrolase 1

UniProtKB Accession Codes:

Database IDs:

Citations:

PubMed ID: 1985963

Title: Cloning and sequencing of cDNA encoding rat GTP cyclohydrolase I. The first enzyme of the tetrahydrobiopterin biosynthetic pathway.

PubMed ID: 1985963

DOI: 10.1016/s0021-9258(17)35238-9

PubMed ID: 7802677

Title: Identification of a rabphilin-3A-interacting protein as GTP cyclohydrolase I in PC12 cells.

PubMed ID: 7802677

DOI: 10.1006/bbrc.1994.2822

PubMed ID: 2557335

Title: Purification and characterization of rat liver GTP cyclohydrolase I. Cooperative binding of GTP to the enzyme.

PubMed ID: 2557335

DOI: 10.1016/s0021-9258(20)88236-2

PubMed ID: 17057711

Title: GTP cyclohydrolase and tetrahydrobiopterin regulate pain sensitivity and persistence.

PubMed ID: 17057711

DOI: 10.1038/nm1490

PubMed ID: 22673903

Title: Quantitative maps of protein phosphorylation sites across 14 different rat organs and tissues.

PubMed ID: 22673903

DOI: 10.1038/ncomms1871

PubMed ID: 11818540

Title: Crystal structure of the stimulatory complex of GTP cyclohydrolase I and its feedback regulatory protein GFRP.

PubMed ID: 11818540

DOI: 10.1073/pnas.022646999

Sequence Information:

  • Length: 241
  • Mass: 27057
  • Checksum: 8226E3319816325B
  • Sequence:
  • MEKPRGVRCT NGFPERELPR PGASRPAEKS RPPEAKGAQP ADAWKAGRPR SEEDNELNLP 
    NLAAAYSSIL RSLGEDPQRQ GLLKTPWRAA TAMQFFTKGY QETISDVLND AIFDEDHDEM 
    VIVKDIDMFS MCEHHLVPFV GRVHIGYLPN KQVLGLSKLA RIVEIYSRRL QVQERLTKQI 
    AVAITEALQP AGVGVVIEAT HMCMVMRGVQ KMNSKTVTST MLGVFREDPK TREEFLTLIR 
    S

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.