Rnf4 | NCBI 29274 - Gene Details

Details for: Rnf4

Gene ID: 29274

Symbol: Rnf4

Description: ring finger protein 4

Associated with

Cellular response to arsenic-containing substance
(GO:0071243)
Cellular response to cytokine stimulus
(GO:0071345)
Cellular response to gamma radiation
(GO:0071480)
Cellular response to hydroxyurea
(GO:0072711)
Cellular response to testosterone stimulus
(GO:0071394)
Cytoplasm
(GO:0005737)
Dna binding
(GO:0003677)
Identical protein binding
(GO:0042802)
Male gonad development
(GO:0008584)
Microtubule end
(GO:1990752)
Negative regulation of protein localization to chromatin
(GO:0120186)
Nuclear androgen receptor binding
(GO:0050681)
Nuclear body
(GO:0016604)
Nuclear estrogen receptor binding
(GO:0030331)
Nucleoplasm
(GO:0005654)
Nucleosome binding
(GO:0031491)
Nucleus
(GO:0005634)
Pml body
(GO:0016605)
Positive regulation of dna-templated transcription
(GO:0045893)
Positive regulation of transcription by rna polymerase ii
(GO:0045944)
Proteasome-mediated ubiquitin-dependent protein catabolic process
(GO:0043161)
Protein autoubiquitination
(GO:0051865)
Protein binding
(GO:0005515)
Protein k6-linked ubiquitination
(GO:0085020)
Protein k11-linked ubiquitination
(GO:0070979)
Protein k48-linked ubiquitination
(GO:0070936)
Protein k63-linked ubiquitination
(GO:0070534)
Protein ubiquitination
(GO:0016567)
Regulation of kinetochore assembly
(GO:0090234)
Regulation of spindle assembly
(GO:0090169)
Response to arsenic-containing substance
(GO:0046685)
Response to estradiol
(GO:0032355)
Response to human chorionic gonadotropin
(GO:0044752)
Spermatogenesis
(GO:0007283)
Sumo polymer binding
(GO:0032184)
Tbp-class protein binding
(GO:0017025)
Transcription factor binding
(GO:0008134)
Ubiquitin-protein transferase activity
(GO:0004842)
Ubiquitin conjugating enzyme binding
(GO:0031624)
Ubiquitin protein ligase activity
(GO:0061630)
Zinc ion binding
(GO:0008270)

Other Information

Proteins

RNF4_RAT

Genular Protein ID: 3518746237

Symbol: RNF4_RAT

Name: N/A

UniProtKB Accession Codes:

O88846

Database IDs:

Citations:

PubMed ID: 9710597

Title: Identification of a novel RING finger protein as a coregulator in steroid receptor-mediated gene transcription.

PubMed ID: 9710597

DOI: 10.1128/mcb.18.9.5128

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 11319220

Title: The RING finger protein SNURF is a bifunctional protein possessing DNA binding activity.

PubMed ID: 11319220

DOI: 10.1074/jbc.m009891200

PubMed ID: 14987998

Title: Transcriptional coregulator SNURF (RNF4) possesses ubiquitin E3 ligase activity.

PubMed ID: 14987998

DOI: 10.1016/s0014-5793(04)00070-5

PubMed ID: 15707587

Title: SUMO-1 promotes association of SNURF (RNF4) with PML nuclear bodies.

PubMed ID: 15707587

DOI: 10.1016/j.yexcr.2004.10.029

PubMed ID: 18408734

Title: RNF4 is a poly-SUMO-specific E3 ubiquitin ligase required for arsenic-induced PML degradation.

PubMed ID: 18408734

DOI: 10.1038/ncb1716

PubMed ID: 20943951

Title: Arsenic-induced SUMO-dependent recruitment of RNF4 into PML nuclear bodies.

PubMed ID: 20943951

DOI: 10.1091/mbc.e10-05-0449

PubMed ID: 22673903

Title: Quantitative maps of protein phosphorylation sites across 14 different rat organs and tissues.

PubMed ID: 22673903

DOI: 10.1038/ncomms1871

PubMed ID: 20681948

Title: RING domain dimerization is essential for RNF4 function.

PubMed ID: 20681948

DOI: 10.1042/bj20100957

Sequence Information:

Length: 194
Mass: 21897
Checksum: 40C13970FC11DFF2
Sequence:

MSTRNPQRKR RGGAVNSRQT QKRTRETTST PEISLEAEPI ELVETVGDEI VDLTCESLEP 
VVVDLTHNDS VVIVEERRRP RRNGRRLRQD HADSCVVSSD DEELSKDKDV YVTTHTPRST 
KDEGTTGLRP SGTVSCPICM DGYSEIVQNG RLIVSTECGH VFCSQCLRDS LKNANTCPTC 
RKKINHKRYH PIYI

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: Rnf4

Associated with

Other Information

Identification of a novel RING finger protein as a coregulator in steroid receptor-mediated gene transcription. PubMed ID: 9710597

The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). PubMed ID: 15489334

The RING finger protein SNURF is a bifunctional protein possessing DNA binding activity. PubMed ID: 11319220

Transcriptional coregulator SNURF (RNF4) possesses ubiquitin E3 ligase activity. PubMed ID: 14987998

SUMO-1 promotes association of SNURF (RNF4) with PML nuclear bodies. PubMed ID: 15707587

RNF4 is a poly-SUMO-specific E3 ubiquitin ligase required for arsenic-induced PML degradation. PubMed ID: 18408734

Arsenic-induced SUMO-dependent recruitment of RNF4 into PML nuclear bodies. PubMed ID: 20943951

Quantitative maps of protein phosphorylation sites across 14 different rat organs and tissues. PubMed ID: 22673903

RING domain dimerization is essential for RNF4 function. PubMed ID: 20681948