Details for: Adora2b

Gene ID: 29316

Symbol: Adora2b

Ensembl ID: ENSRNOG00000002922

Description: adenosine A2B receptor

Associated with

  • Adenosine p1 receptors
    (R-RNO-417973)
  • Class a/1 (rhodopsin-like receptors)
    (R-RNO-373076)
  • Gpcr ligand binding
    (R-RNO-500792)
  • Metabolism of proteins
    (R-RNO-392499)
  • Nucleotide-like (purinergic) receptors
    (R-RNO-418038)
  • Signaling by gpcr
    (R-RNO-372790)
  • Signal transduction
    (R-RNO-162582)
  • Surfactant metabolism
    (R-RNO-5683826)
  • Adenylate cyclase-activating g protein-coupled receptor signaling pathway
    (GO:0007189)
  • Cell surface
    (GO:0009986)
  • Cellular response to extracellular stimulus
    (GO:0031668)
  • Cgmp-mediated signaling
    (GO:0019934)
  • Glutamatergic synapse
    (GO:0098978)
  • G protein-coupled adenosine receptor activity
    (GO:0001609)
  • G protein-coupled adenosine receptor signaling pathway
    (GO:0001973)
  • G protein-coupled receptor activity
    (GO:0004930)
  • Mast cell degranulation
    (GO:0043303)
  • Negative regulation of cell population proliferation
    (GO:0008285)
  • Negative regulation of collagen biosynthetic process
    (GO:0032966)
  • Plasma membrane
    (GO:0005886)
  • Positive regulation of camp-mediated signaling
    (GO:0043950)
  • Positive regulation of catecholamine secretion
    (GO:0033605)
  • Positive regulation of cell population proliferation
    (GO:0008284)
  • Positive regulation of cgmp-mediated signaling
    (GO:0010753)
  • Positive regulation of chemokine production
    (GO:0032722)
  • Positive regulation of chronic inflammatory response to non-antigenic stimulus
    (GO:0002882)
  • Positive regulation of endothelial cell migration
    (GO:0010595)
  • Positive regulation of endothelial cell proliferation
    (GO:0001938)
  • Positive regulation of interleukin-6 production
    (GO:0032755)
  • Positive regulation of mast cell degranulation
    (GO:0043306)
  • Positive regulation of norepinephrine secretion
    (GO:0010701)
  • Positive regulation of steroid biosynthetic process
    (GO:0010893)
  • Positive regulation of vascular endothelial growth factor production
    (GO:0010575)
  • Presynaptic modulation of chemical synaptic transmission
    (GO:0099171)
  • Regulation of cell communication
    (GO:0010646)
  • Regulation of glucose metabolic process
    (GO:0010906)
  • Regulation of signaling
    (GO:0023051)
  • Relaxation of vascular associated smooth muscle
    (GO:0060087)
  • Response to angiotensin
    (GO:1990776)
  • Schaffer collateral - ca1 synapse
    (GO:0098685)
  • Synapse
    (GO:0045202)
  • Vasodilation
    (GO:0042311)

Other Information

Genular Protein ID: 1953884886

Symbol: AA2BR_RAT

Name: Adenosine receptor A2b

UniProtKB Accession Codes:

P29276

Database IDs:

AGR 1 AlphaFoldDB 1 BindingDB 1 CTD 1 ChEBI 4 ChEMBL 1 DrugCentral 1 EMBL 1 GO 32 Gene3D 1 GlyCosmos 1 GlyGen 1 GuidetoPHARMACOLOGY 1 InParanoid 1 IntAct 1 InterPro 4 KEGG 1 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PIR 1 PRINTS 3 PRO 1 PROSITE 2 PROSITE-ProRule 1 PaxDb 1 Pfam 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 RGD 1 Reactome 2 RefSeq 1 SMART 1 SMR 1 STRING 1 SUPFAM 1 UCSC 1 UniProtKB 1 eggNOG 1

Citations:

PubMed ID: 1584214

Title: Molecular cloning and expression of the cDNA for a novel A2-adenosine receptor subtype.

PubMed ID: 1584214

DOI: 10.1210/mend.6.3.1584214

PubMed ID: 1333049

Title: RFL9 encodes an A2b-adenosine receptor.

PubMed ID: 1333049

DOI: 10.1210/mend.6.10.1333049

Sequence Information:

  • Length: 332
  • Mass: 36367
  • Checksum: F0ABAB5CCACA8858
  • Sequence:
    • MQLETQDALY VALELVIAAL AVAGNVLVCA AVGASSALQT PTNYFLVSLA TADVAVGLFA 
IPFAITISLG FCTDFHSCLF LACFVLVLTQ SSIFSLLAVA VDRYLAIRVP LRYKGLVTGT 
RARGIIAVLW VLAFGIGLTP FLGWNSKDRA TSNCTEPGDG ITNKSCCPVK CLFENVVPMS 
YMVYFNFFGC VLPPLLIMMV IYIKIFMVAC KQLQHMELME HSRTTLQREI HAAKSLAMIV 
GIFALCWLPV HAINCITLFH PALAKDKPKW VMNVAILLSH ANSVVNPIVY AYRNRDFRYS 
FHRIISRYVL CQTDTKGGSG QAGGQSTFSL SL

Genular Protein ID: 2371866953

Symbol: A6HF93_RAT

Name: N/A

UniProtKB Accession Codes:

A6HF93 B1WBR3

Database IDs:

ARBA 12 Bgee 1 CTD 1 EMBL 2 Ensembl 2 GO 4 Gene3D 1 GeneTree 1 HOGENOM 1 InterPro 4 KEGG 1 NCBI Taxonomy 1 OMA 1 OrthoDB 1 PANTHER 2 PRINTS 3 PROSITE 3 Pfam 1 Proteomes 2 RGD 2 RefSeq 1 RuleBase 1 SMART 1 SMR 1 SUPFAM 1 TreeFam 1

Citations:

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 15057822

Title: Genome sequence of the Brown Norway rat yields insights into mammalian evolution.

PubMed ID: 15057822

DOI: 10.1038/nature02426

Sequence Information:

  • Length: 332
  • Mass: 36353
  • Checksum: F0ABAB5CD3E22ACB
  • Sequence:
    • MQLETQDALY VALELVIAAL AVAGNVLVCA AVGASSALQT PTNYFLVSLA TADVAVGLFA 
IPFAITISLG FCTDFHSCLF LACFVLVLTQ SSIFSLLAVA VDRYLAIRVP LRYKGLVTGT 
RARGIIAVLW VLAFGIGLTP FLGWNSKDRA TSNCTEPGDG ITNKSCCPVK CLFENVVPMS 
YMVYFNFFGC VLPPLLIMMV IYIKIFMVAC KQLQHMELME HSRTTLQREI HAAKSLAMIV 
GIFALCWLPV HAINCITLFH PALAKDKPKW VMNVAILLSH ANSVVNPVVY AYRNRDFRYS 
FHRIISRYVL CQTDTKGGSG QAGGQSTFSL SL

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.