Details for: Gpx4

Gene ID: 29328

Symbol: Gpx4

Ensembl ID: ENSRNOG00000013604

Description: glutathione peroxidase 4

Associated with

Other Information

Genular Protein ID: 3002678860

Symbol: GPX4_RAT

Name: N/A

UniProtKB Accession Codes:

Database IDs:

Citations:

PubMed ID: 7592947

Title: Rat phospholipid-hydroperoxide glutathione peroxidase. cDNA cloning and identification of multiple transcription and translation start sites.

PubMed ID: 7592947

DOI: 10.1074/jbc.270.45.26993

PubMed ID: 14575705

Title: Molecular cloning and functional expression of nucleolar phospholipid hydroperoxide glutathione peroxidase in mammalian cells.

PubMed ID: 14575705

DOI: 10.1016/j.bbrc.2003.09.183

PubMed ID: 12819198

Title: Distinct promoters determine alternative transcription of gpx-4 into phospholipid-hydroperoxide glutathione peroxidase variants.

PubMed ID: 12819198

DOI: 10.1074/jbc.m305327200

PubMed ID: 11344099

Title: Identification of a specific sperm nuclei selenoenzyme necessary for protamine thiol cross-linking during sperm maturation.

PubMed ID: 11344099

DOI: 10.1096/fj.00-0655fje

PubMed ID: 8749327

Title: Molecular cloning and functional expression of a cDNA for rat phospholipid hydroperoxide glutathione peroxidase: 3'-untranslated region of the gene is necessary for functional expression.

PubMed ID: 8749327

DOI: 10.1093/jb/118.5.1061

PubMed ID: 1556123

Title: Phospholipid hydroperoxide glutathione peroxidase of rat testis. Gonadotropin dependence and immunocytochemical identification.

PubMed ID: 1556123

DOI: 10.1016/s0021-9258(18)42673-7

PubMed ID: 9442035

Title: Suppression of leukotriene formation in RBL-2H3 cells that overexpressed phospholipid hydroperoxide glutathione peroxidase.

PubMed ID: 9442035

DOI: 10.1074/jbc.273.4.1990

PubMed ID: 9988735

Title: Mitochondrial phospholipid hydroperoxide glutathione peroxidase plays a major role in preventing oxidative injury to cells.

PubMed ID: 9988735

DOI: 10.1074/jbc.274.8.4924

PubMed ID: 10506188

Title: Mitochondrial phospholipid hydroperoxide glutathione peroxidase suppresses apoptosis mediated by a mitochondrial death pathway.

PubMed ID: 10506188

DOI: 10.1074/jbc.274.41.29294

PubMed ID: 10998361

Title: Mitochondrial phospholipid hydroperoxide glutathione peroxidase inhibits the release of cytochrome c from mitochondria by suppressing the peroxidation of cardiolipin in hypoglycaemia-induced apoptosis.

PubMed ID: 10998361

DOI: 10.1042/0264-6021:3510183

PubMed ID: 11010961

Title: Involvement of phospholipid hydroperoxide glutathione peroxidase in the modulation of prostaglandin D2 synthesis.

PubMed ID: 11010961

DOI: 10.1074/jbc.m003191200

PubMed ID: 19423663

Title: Identification of novel immunodominant epididymal sperm proteins using combinatorial approach.

PubMed ID: 19423663

DOI: 10.1530/rep-09-0052

PubMed ID: 22673903

Title: Quantitative maps of protein phosphorylation sites across 14 different rat organs and tissues.

PubMed ID: 22673903

DOI: 10.1038/ncomms1871

Sequence Information:

  • Length: 197
  • Mass: 22225
  • Checksum: 83FF001A5A42F814
  • Sequence:
  • MSWGRLSRLL KPALLCGALA VPGLAGTMCA SRDDWRCARS MHEFAAKDID GHMVCLDKYR 
    GCVCIVTNVA SQUGKTDVNY TQLVDLHARY AECGLRILAF PCNQFGRQEP GSNQEIKEFA 
    AGYNVRFDMY SKICVNGDDA HPLWKWMKVQ PKGRGMLGNA IKWNFTKFLI DKNGCVVKRY 
    GPMEEPQVIE KDLPCYL

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.