Oprk1 | ENSRNOG00000007647 | NCBI 29335

Details for: Oprk1

Gene ID: 29335

Symbol: Oprk1

Ensembl ID: ENSRNOG00000007647

Description: opioid receptor, kappa 1

Associated with

Class a/1 (rhodopsin-like receptors)
(R-RNO-373076)
G alpha (i) signalling events
(R-RNO-418594)
Gpcr downstream signalling
(R-RNO-388396)
Gpcr ligand binding
(R-RNO-500792)
Peptide ligand-binding receptors
(R-RNO-375276)
Signaling by gpcr
(R-RNO-372790)
Signal transduction
(R-RNO-162582)
Adenylate cyclase-inhibiting opioid receptor signaling pathway
(GO:0031635)
Axon terminus
(GO:0043679)
Behavioral response to cocaine
(GO:0048148)
Cellular response to glucose stimulus
(GO:0071333)
Cellular response to lipopolysaccharide
(GO:0071222)
Conditioned place preference
(GO:1990708)
Cytosol
(GO:0005829)
Defense response to virus
(GO:0051607)
Dendrite
(GO:0030425)
Dynorphin receptor activity
(GO:0038048)
Eating behavior
(GO:0042755)
Estrous cycle
(GO:0044849)
G protein-coupled opioid receptor activity
(GO:0004985)
G protein-coupled opioid receptor signaling pathway
(GO:0038003)
Immune response
(GO:0006955)
Locomotory behavior
(GO:0007626)
Maternal behavior
(GO:0042711)
Membrane
(GO:0016020)
Mitochondrion
(GO:0005739)
Negative regulation of luteinizing hormone secretion
(GO:0033685)
Neuronal cell body
(GO:0043025)
Neuron projection
(GO:0043005)
Neuropeptide binding
(GO:0042923)
Neuropeptide signaling pathway
(GO:0007218)
Nucleoplasm
(GO:0005654)
Perikaryon
(GO:0043204)
Phospholipase c-activating g protein-coupled receptor signaling pathway
(GO:0007200)
Plasma membrane
(GO:0005886)
Positive regulation of dopamine secretion
(GO:0033603)
Positive regulation of eating behavior
(GO:1904000)
Positive regulation of neuronal action potential
(GO:1904457)
Positive regulation of p38mapk cascade
(GO:1900745)
Positive regulation of potassium ion transmembrane transport
(GO:1901381)
Postsynaptic membrane
(GO:0045211)
Presynaptic membrane
(GO:0042734)
Protein binding
(GO:0005515)
Receptor serine/threonine kinase binding
(GO:0033612)
Regulation of saliva secretion
(GO:0046877)
Response to acrylamide
(GO:1903937)
Response to auditory stimulus
(GO:0010996)
Response to cocaine
(GO:0042220)
Response to estrogen
(GO:0043627)
Response to ethanol
(GO:0045471)
Response to insulin
(GO:0032868)
Response to nicotine
(GO:0035094)
Sarcolemma
(GO:0042383)
Sarcoplasmic reticulum
(GO:0016529)
Sensory perception of pain
(GO:0019233)
Sensory perception of temperature stimulus
(GO:0050951)
Synaptic vesicle membrane
(GO:0030672)
T-tubule
(GO:0030315)

Other Information

Proteins

Kappa-type opioid receptor

Genular Protein ID: 293310604

Symbol: OPRK_RAT

Name: Kappa-type opioid receptor

UniProtKB Accession Codes:

P34975

Database IDs:

Citations:

PubMed ID: 8240267

Title: Molecular cloning of a rat kappa opioid receptor reveals sequence similarities to the mu and delta opioid receptors.

PubMed ID: 8240267

DOI: 10.1042/bj2950625

PubMed ID: 8103466

Title: Cloning and expression of a cDNA for the rat kappa-opioid receptor.

PubMed ID: 8103466

DOI: 10.1016/0014-5793(93)80240-u

PubMed ID: 8240268

Title: Molecular cloning and expression of a rat kappa opioid receptor.

PubMed ID: 8240268

DOI: 10.1042/bj2950629

PubMed ID: 8234341

Title: Cloning and pharmacological characterization of a rat kappa opioid receptor.

PubMed ID: 8234341

DOI: 10.1073/pnas.90.21.9954

PubMed ID: 8396539

Title: cDNA cloning and pharmacological characterization of an opioid receptor with high affinities for kappa-subtype-selective ligands.

PubMed ID: 8396539

DOI: 10.1016/0014-5793(93)80923-i

PubMed ID: 7896774

Title: Structure and expression of a rat kappa opioid receptor gene.

PubMed ID: 7896774

DOI: 10.1074/jbc.270.12.6421

PubMed ID: 20358363

Title: Role of kappa-opioid receptors in the effects of salvinorin A and ketamine on attention in rats.

PubMed ID: 20358363

DOI: 10.1007/s00213-010-1834-7

Sequence Information:

Length: 380
Mass: 42688
Checksum: 107FEEDB09886F92
Sequence:

MESPIQIFRG EPGPTCAPSA CLLPNSSSWF PNWAESDSNG SVGSEDQQLE PAHISPAIPV 
IITAVYSVVF VVGLVGNSLV MFVIIRYTKM KTATNIYIFN LALADALVTT TMPFQSAVYL 
MNSWPFGDVL CKIVISIDYY NMFTSIFTLT MMSVDRYIAV CHPVKALDFR TPLKAKIINI 
CIWLLASSVG ISAIVLGGTK VREDVDVIEC SLQFPDDEYS WWDLFMKICV FVFAFVIPVL 
IIIVCYTLMI LRLKSVRLLS GSREKDRNLR RITKLVLVVV AVFIICWTPI HIFILVEALG 
STSHSTAVLS SYYFCIALGY TNSSLNPVLY AFLDENFKRC FRDFCFPIKM RMERQSTNRV 
RNTVQDPASM RDVGGMNKPV

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: Oprk1

Associated with

Other Information

Molecular cloning of a rat kappa opioid receptor reveals sequence similarities to the mu and delta opioid receptors. PubMed ID: 8240267

Cloning and expression of a cDNA for the rat kappa-opioid receptor. PubMed ID: 8103466

Molecular cloning and expression of a rat kappa opioid receptor. PubMed ID: 8240268

Cloning and pharmacological characterization of a rat kappa opioid receptor. PubMed ID: 8234341

cDNA cloning and pharmacological characterization of an opioid receptor with high affinities for kappa-subtype-selective ligands. PubMed ID: 8396539

Structure and expression of a rat kappa opioid receptor gene. PubMed ID: 7896774

Role of kappa-opioid receptors in the effects of salvinorin A and ketamine on attention in rats. PubMed ID: 20358363