Details for: Bmp2

Gene ID: 29373

Symbol: Bmp2

Ensembl ID: ENSRNOG00000071010

Description: bone morphogenetic protein 2

Associated with

  • Elastic fibre formation
    (R-RNO-1566948)
  • Extracellular matrix organization
    (R-RNO-1474244)
  • Molecules associated with elastic fibres
    (R-RNO-2129379)
  • Signaling by bmp
    (R-RNO-201451)
  • Signaling by tgfb family members
    (R-RNO-9006936)
  • Signal transduction
    (R-RNO-162582)
  • Ameloblast differentiation
    (GO:0036305)
  • Animal organ morphogenesis
    (GO:0009887)
  • Aortic valve development
    (GO:0003176)
  • Astrocyte differentiation
    (GO:0048708)
  • Atrioventricular valve morphogenesis
    (GO:0003181)
  • Bmp receptor binding
    (GO:0070700)
  • Bmp signaling pathway
    (GO:0030509)
  • Bone mineralization
    (GO:0030282)
  • Branching involved in ureteric bud morphogenesis
    (GO:0001658)
  • Cardiac atrium formation
    (GO:0003210)
  • Cardiac epithelial to mesenchymal transition
    (GO:0060317)
  • Cardiac muscle cell differentiation
    (GO:0055007)
  • Cardiac muscle hypertrophy in response to stress
    (GO:0014898)
  • Cardiac muscle tissue morphogenesis
    (GO:0055008)
  • Cardiocyte differentiation
    (GO:0035051)
  • Cell fate commitment
    (GO:0045165)
  • Chondrocyte differentiation
    (GO:0002062)
  • Co-receptor binding
    (GO:0039706)
  • Corticotropin hormone secreting cell differentiation
    (GO:0060128)
  • Cytokine activity
    (GO:0005125)
  • Embryonic heart tube anterior/posterior pattern specification
    (GO:0035054)
  • Endocardial cushion formation
    (GO:0003272)
  • Endocardial cushion morphogenesis
    (GO:0003203)
  • Endodermal-mesodermal cell signaling
    (GO:0003133)
  • Epithelial to mesenchymal transition
    (GO:0001837)
  • Gene expression
    (GO:0010467)
  • Growth factor activity
    (GO:0008083)
  • Heart development
    (GO:0007507)
  • Heart induction
    (GO:0003129)
  • Identical protein binding
    (GO:0042802)
  • Inflammatory response
    (GO:0006954)
  • Inner ear development
    (GO:0048839)
  • In utero embryonic development
    (GO:0001701)
  • Mesenchymal cell differentiation
    (GO:0048762)
  • Negative regulation of aldosterone biosynthetic process
    (GO:0032348)
  • Negative regulation of calcium-independent cell-cell adhesion
    (GO:0051042)
  • Negative regulation of cell cycle
    (GO:0045786)
  • Negative regulation of cell population proliferation
    (GO:0008285)
  • Negative regulation of dna-templated transcription
    (GO:0045892)
  • Negative regulation of fat cell differentiation
    (GO:0045599)
  • Negative regulation of gene expression
    (GO:0010629)
  • Negative regulation of insulin-like growth factor receptor signaling pathway
    (GO:0043569)
  • Negative regulation of muscle cell differentiation
    (GO:0051148)
  • Negative regulation of smooth muscle cell proliferation
    (GO:0048662)
  • Negative regulation of steroid biosynthetic process
    (GO:0010894)
  • Negative regulation of transcription by rna polymerase ii
    (GO:0000122)
  • Negative regulation of transforming growth factor beta receptor signaling pathway
    (GO:0030512)
  • Notch signaling pathway
    (GO:0007219)
  • Odontogenesis of dentin-containing tooth
    (GO:0042475)
  • Osteoblast differentiation
    (GO:0001649)
  • Osteoclast differentiation
    (GO:0030316)
  • Ovulation cycle
    (GO:0042698)
  • Pericardium development
    (GO:0060039)
  • Phosphatase activator activity
    (GO:0019211)
  • Positive regulation of apoptotic process
    (GO:0043065)
  • Positive regulation of astrocyte differentiation
    (GO:0048711)
  • Positive regulation of bone mineralization
    (GO:0030501)
  • Positive regulation of cell migration
    (GO:0030335)
  • Positive regulation of cell population proliferation
    (GO:0008284)
  • Positive regulation of dna-templated transcription
    (GO:0045893)
  • Positive regulation of epithelial cell differentiation
    (GO:0030858)
  • Positive regulation of epithelial to mesenchymal transition
    (GO:0010718)
  • Positive regulation of extracellular matrix constituent secretion
    (GO:0003331)
  • Positive regulation of fat cell differentiation
    (GO:0045600)
  • Positive regulation of gene expression
    (GO:0010628)
  • Positive regulation of mapk cascade
    (GO:0043410)
  • Positive regulation of neurogenesis
    (GO:0050769)
  • Positive regulation of neuron differentiation
    (GO:0045666)
  • Positive regulation of odontogenesis
    (GO:0042482)
  • Positive regulation of ossification
    (GO:0045778)
  • Positive regulation of osteoblast differentiation
    (GO:0045669)
  • Positive regulation of osteoblast proliferation
    (GO:0033690)
  • Positive regulation of peroxisome proliferator activated receptor signaling pathway
    (GO:0035360)
  • Positive regulation of protein phosphorylation
    (GO:0001934)
  • Positive regulation of transcription by rna polymerase ii
    (GO:0045944)
  • Positive regulation of wnt signaling pathway
    (GO:0030177)
  • Protein destabilization
    (GO:0031648)
  • Protein domain specific binding
    (GO:0019904)
  • Protein serine/threonine kinase activator activity
    (GO:0043539)
  • Proteoglycan metabolic process
    (GO:0006029)
  • Receptor ligand activity
    (GO:0048018)
  • Regulation of dna-templated transcription
    (GO:0006355)
  • Regulation of odontogenesis of dentin-containing tooth
    (GO:0042487)
  • Response to bacterium
    (GO:0009617)
  • Response to hypoxia
    (GO:0001666)
  • Response to mechanical stimulus
    (GO:0009612)
  • Response to retinoic acid
    (GO:0032526)
  • Telencephalon development
    (GO:0021537)
  • Telencephalon regionalization
    (GO:0021978)
  • Thyroid-stimulating hormone-secreting cell differentiation
    (GO:0060129)
  • Transcription by rna polymerase ii
    (GO:0006366)

Other Information

Genular Protein ID: 2816120821

Symbol: BMP2_RAT

Name: Bone morphogenetic protein 2

UniProtKB Accession Codes:

P49001

Database IDs:

AGR 1 AlphaFoldDB 1 CDD 1 CTD 1 EMBL 1 GO 100 Gene3D 2 GlyCosmos 1 GlyGen 1 InParanoid 1 InterPro 6 KEGG 1 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PIR 1 PRINTS 1 PRO 1 PROSITE 2 PaxDb 1 Pfam 2 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 RGD 1 Reactome 2 RefSeq 1 SAM 1 SMART 1 SMR 1 STRING 1 SUPFAM 1 UCSC 1 UniProtKB 3 eggNOG 1 jPOST 1

Sequence Information:

  • Length: 393
  • Mass: 44383
  • Checksum: 7D20865852E0F213
  • Sequence:
    • MVAGTRCLLV LLLPQVLLGG AAGLIPELGR KKFAGASRPL SRPSEDVLSE FELRLLSMFG 
LKQRPTPSKD VVVPPYMLDL YRRHSGQPGA LAPDHRLERA ASRANTVLSF HHEEAIEELS 
EMSGKTSRRF FFNLSSVPTD EFLTSAELQI FREQMQEALG NSSFQHRINI YEIIKPATAS 
SKFPVTRLLD TRLVTQNTSQ WESFDVTPAV MRWTAQGHTN HGFVVEVAHL EEKPGVSKRH 
VRISRSLHQD EHSWSQVRPL LVTFGHDGKG HPLHKREKRQ AKHKQRKRLK SSCKRHPLYV 
DFSDVGWNDW IVAPPGYHAF YCHGECPFPL ADHLNSTNHA IVQTLVNSVN SKIPKACCVP 
TELSAISMLY LDENEKVVLK NYQDMVVEGC GCR

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.