Irs2 | ENSRNOG00000023509 | NCBI 29376

Details for: Irs2

Gene ID: 29376

Symbol: Irs2

Ensembl ID: ENSRNOG00000023509

Description: insulin receptor substrate 2

Associated with

Axon guidance
(R-RNO-422475)
Cytokine signaling in immune system
(R-RNO-1280215)
Developmental biology
(R-RNO-1266738)
Erythropoietin activates phosphoinositide-3-kinase (pi3k)
(R-RNO-9027276)
Erythropoietin activates ras
(R-RNO-9027284)
Igf1r signaling cascade
(R-RNO-2428924)
Immune system
(R-RNO-168256)
Insulin receptor signalling cascade
(R-RNO-74751)
Interleukin-7 signaling
(R-RNO-1266695)
Intracellular signaling by second messengers
(R-RNO-9006925)
Irs-mediated signalling
(R-RNO-112399)
Irs-related events triggered by igf1r
(R-RNO-2428928)
Irs activation
(R-RNO-74713)
Mapk1/mapk3 signaling
(R-RNO-5684996)
Mapk family signaling cascades
(R-RNO-5683057)
Negative regulation of the pi3k/akt network
(R-RNO-199418)
Nervous system development
(R-RNO-9675108)
Pi3k/akt activation
(R-RNO-198203)
Pi3k cascade
(R-RNO-109704)
Pi5p, pp2a and ier3 regulate pi3k/akt signaling
(R-RNO-6811558)
Pip3 activates akt signaling
(R-RNO-1257604)
Raf/map kinase cascade
(R-RNO-5673001)
Ret signaling
(R-RNO-8853659)
Signal attenuation
(R-RNO-74749)
Signaling by erythropoietin
(R-RNO-9006335)
Signaling by insulin receptor
(R-RNO-74752)
Signaling by interleukins
(R-RNO-449147)
Signaling by ntrk1 (trka)
(R-RNO-187037)
Signaling by ntrks
(R-RNO-166520)
Signaling by receptor tyrosine kinases
(R-RNO-9006934)
Signaling by type 1 insulin-like growth factor 1 receptor (igf1r)
(R-RNO-2404192)
Signal transduction
(R-RNO-162582)
Sos-mediated signalling
(R-RNO-112412)
14-3-3 protein binding
(GO:0071889)
Brain development
(GO:0007420)
Cell migration
(GO:0016477)
Cell population proliferation
(GO:0008283)
Cellular response to glucose stimulus
(GO:0071333)
Cellular response to insulin stimulus
(GO:0032869)
Cellular response to peptide
(GO:1901653)
Cytosol
(GO:0005829)
Epithelial cell migration
(GO:0010631)
Insulin receptor binding
(GO:0005158)
Insulin receptor signaling pathway
(GO:0008286)
Mammary gland development
(GO:0030879)
Negative regulation of b cell apoptotic process
(GO:0002903)
Negative regulation of long-chain fatty acid import across plasma membrane
(GO:0010748)
Phosphatidylinositol 3-kinase activator activity
(GO:0141038)
Phosphatidylinositol 3-kinase binding
(GO:0043548)
Plasma membrane
(GO:0005886)
Positive regulation of b cell proliferation
(GO:0030890)
Positive regulation of cell population proliferation
(GO:0008284)
Positive regulation of epithelial cell migration
(GO:0010634)
Positive regulation of fatty acid beta-oxidation
(GO:0032000)
Positive regulation of glucose import
(GO:0046326)
Positive regulation of glucose metabolic process
(GO:0010907)
Positive regulation of glycogen biosynthetic process
(GO:0045725)
Positive regulation of insulin secretion
(GO:0032024)
Positive regulation of mesenchymal cell proliferation
(GO:0002053)
Positive regulation of phosphatidylinositol 3-kinase/protein kinase b signal transduction
(GO:0051897)
Positive regulation of type b pancreatic cell proliferation
(GO:1904692)
Protein-macromolecule adaptor activity
(GO:0030674)
Protein binding
(GO:0005515)
Protein domain specific binding
(GO:0019904)
Protein kinase binding
(GO:0019901)
Protein phosphatase binding
(GO:0019903)
Response to glucose
(GO:0009749)
Transmembrane receptor protein tyrosine kinase adaptor activity
(GO:0005068)
Type b pancreatic cell proliferation
(GO:0044342)

Other Information

Proteins

F1MAL5_RAT

Genular Protein ID: 2877111246

Symbol: F1MAL5_RAT

Name: N/A

UniProtKB Accession Codes:

F1MAL5

Database IDs:

Citations:

PubMed ID: 15057822

Title: Genome sequence of the Brown Norway rat yields insights into mammalian evolution.

PubMed ID: 15057822

DOI: 10.1038/nature02426

PubMed ID: 22673903

Title: Quantitative maps of protein phosphorylation sites across 14 different rat organs and tissues.

PubMed ID: 22673903

Sequence Information:

Length: 1327
Mass: 137239
Checksum: EBD7BB57DD5D031E
Sequence:

MASAPLPGPP ASAGGDGPNL NNNNNNNNNH SVRKCGYLRK QKHGHKRFFV LRGPGTGGEE 
AAAAGGSPPQ PPRLEYYESE KKWKSKAGAP KRVIALDCCL NINKRADAKH KYLIALYTKD 
EYFAVAAENE QEQEGWYRAL TDLVSEGRSG DGGSGTTGGS CSASLPGALG GSAGAAGCDD 
NYGLVTPATA VYREVWQVNL KPKGLGQSKN LTGVYRLCLS ARTIGFVKLN CEQPSVTLQL 
MNIRRCGHSD SFFFIEVGRS AVTGPGELWM QADDSVVAQN IHETILEAMK ALKELFEFRP 
RSKSQSSGSS ATHPISVPGA RRHHHLVNLP PSQTGLVRRS RTDSLAATPP AAKCTSCRVR 
TASEGDGGAA GGAGTAGGRP MSVAGSPLSP GPVRAPLSRS HTLSAGCGGR PSKVALAPAG 
GALQHSRSMS MPVAHSPPAA TSPGSLSSSS GHGSGSYPLP PGSHPHLPHP LHHPQCQRPS 
SGSASASGSP SDPGFMSLDE YGSSPGDLRA FSSHRSNTPE SIAETPPARD GSGGELYGYM 
SMDRPLSHCG RPYRRVSGDG AQDLDRGLRK RTYSLTTPAR QRQVPQPSSA SLDEYTLMRA 
TFSGSSGRLC PSLPASSPKV AYNPYPEDYG DIEIGSHKSS SSNLGADDGY MPMTPGAALR 
SGGPNSCKSD DYMPMSPTSV SAPKQILQPR SAAALPPSGA AVPAPPSGAG RTFPVNGGGY 
KASSPAESSP EDSGYMRMWC GSKLSMENPD PKLLPNGDYL NMSPSEAGTA GTPPDFFSAA 
LRPGGEALKG VPGHCYSSLP RSYKAPCTCG GGDNDQYVLM SSPVGRILEE ERLEPQATPG 
AGTFGAAGGS HTQPHHSAVP SSMRPSGIVG RPEGFLGQRC RAVRPTRLSL EGLQTLPSMQ 
EYPLPTEPKS PGEYINIDFG EGGTRLSPPA PPLLASAASS SSLLSASSPA SSLGSGTPGT 
SSDSRQRSPL SDYMNLDFSS PKSPKPSTRS GDTVGSIDGL LSPEASSPYP PLPPRPSASP 
SSLQQPLPPA PGDLYRLPPA TAATSQGPTA GSSMSSEPGD NGDYTEMAFG VAATPPQPIA 
APPKPEGARV TSPTSGLKRL SLMDQVSGVE AFLQVSQPPD PHRGAKVIRA DPQGGRRRHS 
SETFSSTTTV TPVSPSFAHN SKRHNSASVE NVSLRKSSEG NSILGGSDEP STSPGQAQPS 
AGVPPAPQAR PWNPGQPGAL IGCPGGSSSP MRRETSVGFQ NGLNYIAIDV RGEQGSLAQS 
QPQHPQPGDK NSWGRTRSLG GLLGTVGGSG TSGVCGGPGT GALPSASTYA SIDFLSHHLK 
EATVVKE

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.