Cxcr2 | ENSRNOG00000063618 | NCBI 29385

Details for: Cxcr2

Gene ID: 29385

Symbol: Cxcr2

Ensembl ID: ENSRNOG00000063618

Description: C-X-C motif chemokine receptor 2

Associated with

Chemokine receptors bind chemokines
(R-RNO-380108)
Class a/1 (rhodopsin-like receptors)
(R-RNO-373076)
G alpha (i) signalling events
(R-RNO-418594)
Gpcr downstream signalling
(R-RNO-388396)
Gpcr ligand binding
(R-RNO-500792)
Immune system
(R-RNO-168256)
Innate immune system
(R-RNO-168249)
Neutrophil degranulation
(R-RNO-6798695)
Peptide ligand-binding receptors
(R-RNO-375276)
Signaling by gpcr
(R-RNO-372790)
Signal transduction
(R-RNO-162582)
Acute inflammatory response to antigenic stimulus
(GO:0002438)
C-c chemokine binding
(GO:0019957)
C-c chemokine receptor activity
(GO:0016493)
C-x-c chemokine receptor activity
(GO:0016494)
Calcium-mediated signaling
(GO:0019722)
Cell surface
(GO:0009986)
Cell surface receptor signaling pathway
(GO:0007166)
Cellular defense response
(GO:0006968)
Chemokine receptor activity
(GO:0004950)
Chemotaxis
(GO:0006935)
External side of plasma membrane
(GO:0009897)
G protein-coupled receptor activity
(GO:0004930)
Immune response
(GO:0006955)
Interleukin-8 binding
(GO:0019959)
Interleukin-8 receptor activity
(GO:0004918)
Interleukin-8-mediated signaling pathway
(GO:0038112)
Mast cell granule
(GO:0042629)
Membrane
(GO:0016020)
Metanephric tubule morphogenesis
(GO:0072173)
Microtubule cytoskeleton
(GO:0015630)
Midbrain development
(GO:0030901)
Mitotic spindle
(GO:0072686)
Negative regulation of apoptotic process
(GO:0043066)
Negative regulation of neutrophil apoptotic process
(GO:0033030)
Neutrophil activation
(GO:0042119)
Neutrophil chemotaxis
(GO:0030593)
Nucleoplasm
(GO:0005654)
Phospholipase c-activating g protein-coupled receptor signaling pathway
(GO:0007200)
Plasma membrane
(GO:0005886)
Positive regulation of angiogenesis
(GO:0045766)
Positive regulation of cardiac muscle cell apoptotic process
(GO:0010666)
Positive regulation of cell population proliferation
(GO:0008284)
Positive regulation of cytosolic calcium ion concentration
(GO:0007204)
Positive regulation of leukocyte chemotaxis
(GO:0002690)
Positive regulation of neutrophil chemotaxis
(GO:0090023)
Positive regulation of vascular permeability
(GO:0043117)
Receptor internalization
(GO:0031623)

Other Information

Proteins

C-X-C chemokine receptor type 2

Genular Protein ID: 2765570287

Symbol: CXCR2_RAT

Name: C-X-C chemokine receptor type 2

UniProtKB Accession Codes:

P35407

Database IDs:

Citations:

PubMed ID: 9218548

Title: Molecular cloning and characterization of a cDNA encoding the rat interleukin-8 receptor.

PubMed ID: 9218548

DOI: 10.1016/s0005-2736(97)00065-5

PubMed ID: 8955112

Title: Identification of two rat genes orthologous to the human interleukin-8 receptors.

PubMed ID: 8955112

DOI: 10.1074/jbc.271.51.32770

Sequence Information:

Length: 359
Mass: 40532
Checksum: EF547326A074ABDD
Sequence:

MGEIRVDNFS LEDFFSGDID SYNYSSDPPF TLSDAAPCPS ANLDINRYAV VVIYVLVTLL 
SLVGNSLVML VILYNRSTCS VTDVYLLNLA IADLFFALTL PVWAASKVNG WIFGSFLCKV 
FSFLQEITFY SSVLLLACIS MDRYLAIVHA TSTLIQKRHL VKFVCITMWF LSLVLSLPIF 
ILRTTVKANP STVVCYENIG NNTSKWRVVL RILPQTYGFL LPLLIMLFCY GFTLRTLFKA 
HMGQKHRAMR VIFAVVLVFL LCWLPYNIVL FTDTLMRTKL IKETCERQNE INKALEATEI 
LGFLHSCLNP IIYAFIGQKF RHGLLKIMAN YGLVSKEFLA KEGRPSFVGS SSANTSTTL

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.