Men1 | ENSRNOG00000021054 | NCBI 29417

Details for: Men1

Gene ID: 29417

Symbol: Men1

Ensembl ID: ENSRNOG00000021054

Description: menin 1

Associated with

Epigenetic regulation of gene expression
(R-RNO-212165)
Formation of wdr5-containing histone-modifying complexes
(R-RNO-9772755)
Gene expression (transcription)
(R-RNO-74160)
Generic transcription pathway
(R-RNO-212436)
Metabolism of proteins
(R-RNO-392499)
Post-translational protein modification
(R-RNO-597592)
Post-translational protein phosphorylation
(R-RNO-8957275)
Regulation of insulin-like growth factor (igf) transport and uptake by insulin-like growth factor binding proteins (igfbps)
(R-RNO-381426)
Rna polymerase ii transcription
(R-RNO-73857)
Signaling by tgf-beta receptor complex
(R-RNO-170834)
Signaling by tgfb family members
(R-RNO-9006936)
Signal transduction
(R-RNO-162582)
Smad2/smad3:smad4 heterotrimer regulates transcription
(R-RNO-2173796)
Transcriptional activity of smad2/smad3:smad4 heterotrimer
(R-RNO-2173793)
Cell division
(GO:0051301)
Cell population proliferation
(GO:0008283)
Cellular response to glucose stimulus
(GO:0071333)
Cellular response to peptide hormone stimulus
(GO:0071375)
Chromatin
(GO:0000785)
Chromatin binding
(GO:0003682)
Chromatin remodeling
(GO:0006338)
Chromosome, telomeric region
(GO:0000781)
Cleavage furrow
(GO:0032154)
Cytoplasm
(GO:0005737)
Cytosol
(GO:0005829)
Decidualization
(GO:0046697)
Dna-binding transcription activator activity
(GO:0001216)
Dna binding
(GO:0003677)
Dna damage response
(GO:0006974)
Double-stranded dna binding
(GO:0003690)
Embryonic skeletal system morphogenesis
(GO:0048704)
Fibroblast apoptotic process
(GO:0044346)
Fibroblast proliferation
(GO:0048144)
Four-way junction dna binding
(GO:0000400)
Hemopoiesis
(GO:0030097)
Histone methyltransferase complex
(GO:0035097)
Leukocyte homeostasis
(GO:0001776)
Mapk cascade
(GO:0000165)
Maternal process involved in female pregnancy
(GO:0060135)
Mll1 complex
(GO:0071339)
Mll1/2 complex
(GO:0044665)
Negative regulation of cell-substrate adhesion
(GO:0010812)
Negative regulation of cell cycle
(GO:0045786)
Negative regulation of cell cycle g1/s phase transition
(GO:1902807)
Negative regulation of cell population proliferation
(GO:0008285)
Negative regulation of dna-templated transcription
(GO:0045892)
Negative regulation of epithelial cell proliferation
(GO:0050680)
Negative regulation of fibroblast proliferation
(GO:0048147)
Negative regulation of jnk cascade
(GO:0046329)
Negative regulation of organ growth
(GO:0046621)
Negative regulation of osteoblast differentiation
(GO:0045668)
Negative regulation of protein phosphorylation
(GO:0001933)
Negative regulation of stem cell proliferation
(GO:2000647)
Negative regulation of transcription by rna polymerase ii
(GO:0000122)
Negative regulation of type b pancreatic cell proliferation
(GO:1904691)
Nuclear matrix
(GO:0016363)
Nucleoplasm
(GO:0005654)
Nucleus
(GO:0005634)
Organ growth
(GO:0035265)
Ossification
(GO:0001503)
Osteoblast development
(GO:0002076)
Osteoblast fate commitment
(GO:0002051)
Phosphoprotein binding
(GO:0051219)
Positive regulation of cell division
(GO:0051781)
Positive regulation of dna-templated transcription
(GO:0045893)
Positive regulation of fibroblast apoptotic process
(GO:2000271)
Positive regulation of gene expression
(GO:0010628)
Positive regulation of osteoblast differentiation
(GO:0045669)
Positive regulation of stem cell differentiation
(GO:2000738)
Positive regulation of transcription by rna polymerase ii
(GO:0045944)
Positive regulation of transforming growth factor beta receptor signaling pathway
(GO:0030511)
Protein-containing complex
(GO:0032991)
Protein-macromolecule adaptor activity
(GO:0030674)
R-smad binding
(GO:0070412)
Regulation of activin receptor signaling pathway
(GO:0032925)
Regulation of g1/s transition of mitotic cell cycle
(GO:2000045)
Regulation of gene expression
(GO:0010468)
Regulation of transcription by rna polymerase ii
(GO:0006357)
Regulation of type b pancreatic cell proliferation
(GO:0061469)
Response to gamma radiation
(GO:0010332)
Response to transforming growth factor beta
(GO:0071559)
Response to uv
(GO:0009411)
Roof of mouth development
(GO:0060021)
Sequence-specific dna binding
(GO:0043565)
Stem cell differentiation
(GO:0048863)
Stem cell proliferation
(GO:0072089)
T-helper 2 cell differentiation
(GO:0045064)
Transcription cis-regulatory region binding
(GO:0000976)
Transcription initiation-coupled chromatin remodeling
(GO:0045815)
Transcription repressor complex
(GO:0017053)
Type b pancreatic cell differentiation
(GO:0003309)
Type b pancreatic cell proliferation
(GO:0044342)
Y-form dna binding
(GO:0000403)

Other Information

Proteins

Menin
A6HZG1_RAT

Genular Protein ID: 380210794

Symbol: MEN1_RAT

Name: Menin

UniProtKB Accession Codes:

Q9WVR8 D3ZCA2

Database IDs:

Citations:

PubMed ID: 10612420

Title: Structure and distribution of rat menin mRNA.

PubMed ID: 10612420

DOI: 10.1016/s0303-7207(99)00150-1

PubMed ID: 10524203

Title: Primary structure, gene expression and chromosomal mapping of rodent homologs of the MEN1 tumor suppressor gene.

PubMed ID: 10524203

DOI: 10.1016/s0167-4781(99)00089-5

PubMed ID: 11274402

Title: Inactivation of menin, a Smad3-interacting protein, blocks transforming growth factor type beta signaling.

PubMed ID: 11274402

DOI: 10.1073/pnas.061358098

PubMed ID: 22673903

Title: Quantitative maps of protein phosphorylation sites across 14 different rat organs and tissues.

PubMed ID: 22673903

DOI: 10.1038/ncomms1871

Sequence Information:

Length: 610
Mass: 67335
Checksum: F9D2078B02363E32
Sequence:

MGLKAAQKTL FPLRSIDDVV RLFAAELGRE EPDLVLLSLV LGFVEHFLAV NRVIPTNVPE 
LTFQPSPAPD PPGGLTYFPV ADLSIIAALY ARFTAQIRGA VDLSLYPREG GVSSRELVKK 
VSDVIWNSLS RSYFKDRAHI QSLFSFITGT KLDSSGVAFA VVGACQALGL RDVHLALSED 
HAWVVFGSNG EQTAEVTWHG KGNEDRRGQT VNAGVAERSW LYLKGSYMRC DRKMEVAFMV 
CAINPSIDLH TDSLELLQLQ QKLLWLLYDL GHLERYPMAL GNLADLEELE PTPGRPDPLT 
LYHKGIASAK TYYQDEHIYP YMYLAGYHCR NRNVREALQA WADTATVIQD YNYCREDEEI 
YKEFFEVAND VIPNLLKEAA SLLEAGEERP GEQAQGTQGQ GSALQDPECF AHLLRFYDGI 
CKWEEGSPTP VLHVGWATFL VQSLGRFEGQ VRQKVHIVSR EAEAAEAEEP WGDEAREGRR 
RGPRRESKPE EPPPPKKPAL DKGPGSGQSA GSGPPRKTSG TVSGTARGTE VSSAAQAPAP 
AASPPPEGPV LTFQSEKMKG MKELLVATKI NSSAIKLQLT AQSQVQMKKQ KVSTPSDYTL 
SFLKRQRKGL

Genular Protein ID: 1995247611

Symbol: A6HZG1_RAT

Name: N/A

UniProtKB Accession Codes:

A6HZG1

Database IDs:

Sequence Information:

Length: 616
Mass: 67900
Checksum: 532BCDB4F4489660
Sequence:

MPPPAAMGLK AAQKTLFPLR SIDDVVRLFA AELGREEPDL VLLSLVLGFV EHFLAVNRVI 
PTNVPELTFQ PSPAPDPPGG LTYFPVADLS IIAALYARFT AQIRGAVDLS LYPREGGVSS 
RELVKKVSDV IWNSLSRSYF KDRAHIQSLF SFITGTKLDS SGVAFAVVGA CQALGLRDVH 
LALSEDHAWV VFGSNGEQTA EVTWHGKGNE DRRGQTVNAG VAERSWLYLK GSYMRCDRKM 
EVAFMVCAIN PSIDLHTDSL ELLQLQQKLL WLLYDLGHLE RYPMALGNLA DLEELEPTPG 
RPDPLTLYHK GIASAKTYYQ DEHIYPYMYL AGYHCRNRNV REALQAWADT ATVIQDYNYC 
REDEEIYKEF FEVANDVIPN LLKEAASLLE AGEERPGEQA QGTQGQGSAL QDPECFAHLL 
RFYDGICKWE EGSPTPVLHV GWATFLVQSL GRFEGQVRQK VHIVSREAEA AEAEEPWGDE 
AREGRRRGPR RESKPEEPPP PKKPALDKGP GSGQSAGSGP PRKTSGTVSG TARGTEVSSA 
AQAPAPAASP PPEGPVLTFQ SEKMKGMKEL LVATKINSSA IKLQLTAQSQ VQMKKQKVST 
PSDYTLSFLK RQRKGL

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: Men1

Associated with

Other Information

Structure and distribution of rat menin mRNA. PubMed ID: 10612420

Primary structure, gene expression and chromosomal mapping of rodent homologs of the MEN1 tumor suppressor gene. PubMed ID: 10524203

Inactivation of menin, a Smad3-interacting protein, blocks transforming growth factor type beta signaling. PubMed ID: 11274402

Quantitative maps of protein phosphorylation sites across 14 different rat organs and tissues. PubMed ID: 22673903

Database document:

PubMed ID: 10612420

PubMed ID: 10524203

PubMed ID: 11274402

PubMed ID: 22673903