Numb | ENSRNOG00000009653 | NCBI 29419

Details for: Numb

Gene ID: 29419

Symbol: Numb

Ensembl ID: ENSRNOG00000009653

Description: NUMB, endocytic adaptor protein

Associated with

Axon guidance
(R-RNO-422475)
Degradation of gli1 by the proteasome
(R-RNO-5610780)
Developmental biology
(R-RNO-1266738)
Hedgehog 'off' state
(R-RNO-5610787)
Hedgehog 'on' state
(R-RNO-5632684)
L1cam interactions
(R-RNO-373760)
Recycling pathway of l1
(R-RNO-437239)
Signaling by hedgehog
(R-RNO-5358351)
Signal transduction
(R-RNO-162582)
Adherens junction organization
(GO:0034332)
Alpha-catenin binding
(GO:0045294)
Apical part of cell
(GO:0045177)
Apical plasma membrane
(GO:0016324)
Axonogenesis
(GO:0007409)
Basolateral plasma membrane
(GO:0016323)
Beta-catenin binding
(GO:0008013)
Cadherin binding
(GO:0045296)
Cell differentiation
(GO:0030154)
Clathrin-coated pit
(GO:0005905)
Clathrin-coated vesicle
(GO:0030136)
Cytoplasm
(GO:0005737)
Cytoplasmic vesicle
(GO:0031410)
Dendritic spine
(GO:0043197)
Early endosome
(GO:0005769)
Endosome membrane
(GO:0010008)
Forebrain development
(GO:0030900)
Glutamatergic synapse
(GO:0098978)
Lateral ventricle development
(GO:0021670)
Lung epithelial cell differentiation
(GO:0060487)
Negative regulation of notch signaling pathway
(GO:0045746)
Negative regulation of protein localization to plasma membrane
(GO:1903077)
Nervous system development
(GO:0007399)
Neuroblast division in subventricular zone
(GO:0021849)
Neuroblast proliferation
(GO:0007405)
Nucleus
(GO:0005634)
Phospholipid binding
(GO:0005543)
Plasma membrane
(GO:0005886)
Positive regulation of cell migration
(GO:0030335)
Positive regulation of dendrite morphogenesis
(GO:0050775)
Positive regulation of neurogenesis
(GO:0050769)
Positive regulation of polarized epithelial cell differentiation
(GO:0030862)
Postsynaptic density
(GO:0014069)
Protein binding
(GO:0005515)
Regulation of neuron differentiation
(GO:0045664)
Regulation of postsynapse assembly
(GO:0150052)
Regulation of postsynaptic neurotransmitter receptor internalization
(GO:0099149)

Other Information

Proteins

Q3MUI1_RAT
Q2LC86_RAT

Genular Protein ID: 1153885083

Symbol: Q3MUI1_RAT

Name: N/A

UniProtKB Accession Codes:

Q3MUI1

Database IDs:

Citations:

PubMed ID: 16105844

Title: Phosphorylation of Numb family proteins. Possible involvement of Ca2+/calmodulin-dependent protein kinases.

PubMed ID: 16105844

DOI: 10.1074/jbc.M503912200

Sequence Information:

Length: 592
Mass: 64256
Checksum: 774260F3D736930F
Sequence:

MNKLRQSFRR KKDVYVPEAS RPHQWQTDEE GVRTGKCSFP VKYLGHVEVD ESRGMHICED 
AVKRLKATGK KAVKAVLWVS ADGLRVVDEK TKDLIVDQTI EKVSFCAPDR NFDRAFSYIC 
RDGTTRRWIC HCFMAVKDTG ERLSHAVGCA FAACLERKQK REKECGVTAT FDASRTTFTR 
EGSFRVTTAT EQAEREEIMK QLQDAKKAET DKTVGPSVAP GNSAPSPSSP TSPTLDPTAS 
LEMNNPHAIP RRHAPIEQLA RQGSFRGFPA LSQKMSPFKR QLSLRINELP STMQRKTDFP 
IKNTVPEVEG EAESISSLCS QITSAFSTPC EDPFSSAPMT KPVTLVAPQS PVLQGTEWGQ 
SSGAASPGLF QAGHRRTPSE ADRWLEEVSK SVRAQQPQAS AAPLQPVLQP PPPAAIAPPA 
PPFQGHAFLT SQPVPVGVVP PLQPAFVSTQ SYPVANGMPY PASNVPVVGI TPSQMVANVF 
GTAGHPQATH PHQSPSLAKQ QTFPQYETSS ATTSPFFKPS AQHLNGSAAF NGVDNSGLVS 
GNRPAQVPPG TCPVDPFEAQ WAALESKPKQ RTNPSPTNPF SSDAQKAFEI EL

Genular Protein ID: 606142163

Symbol: Q2LC86_RAT

Name: N/A

UniProtKB Accession Codes:

Q2LC86

Database IDs:

Citations:

PubMed ID: 15632090

Title: Gene and alternative splicing annotation with AIR.

PubMed ID: 15632090

DOI: 10.1101/gr.2889405

Sequence Information:

Length: 592
Mass: 64284
Checksum: 65C4E4EE5EB0171F
Sequence:

MNKLRQSFRR KKDVYVPEAS RPHQWQTDEE GVRTGKCSFP VKYLGHVEVD ESRGMHICED 
AVKRLKATGK KAVKAVLWVS ADGLRVVDEK TKDLIVDQTI EKVSFCAPDR NFDRAFSYIC 
RDGTTRRWIC HCFMAVKDTG ERLSHAVGCA FAACLERKQK REKECGVTAT FDASRTTFTR 
EGSFRVTTAT EQAEREEIMK QLQDAKKAET DKTVGPSVAP GNSAPSPSSP TSPTLDPTAS 
LEMNNPHAIP RRHAPIEQLA RQGSFRGFPA LSQKMSPFKR QLSLRINELP STMQRKTDFP 
IKNTVPEVEG EAESISSLCS QITSAFSTPC EDPFSSAPMT KPVTLVAPQS PVLQGTEWGQ 
SSGAASPGLF QAGHRRTPSE ADRWLEEVSK SVRAQQPQVS AAPLQPVLQP PPPAAIAPPA 
PPFQGHAFLT SQPVPVGVVP PLQPAFVSTQ SYPVANGMPY PASNVPVVGI TPSQMVANVF 
GTAGHPQATH PHQSPSLAKQ QTFPQYETSS ATTSPFFKPS AQHLNGSAAF NGVDNSGLVS 
GNRPAQVPPG TCPVDPFEAQ WAALESKPKQ RTNPSPTNPF SSDAQKAFEI EL

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.