Details for: Pak1
Associated with
Other Information
Genular Protein ID: 1752419108
Symbol: PAK1_RAT
Name: N/A
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 8107774
Title: A brain serine/threonine protein kinase activated by Cdc42 and Rac1.
PubMed ID: 8107774
DOI: 10.1038/367040a0
PubMed ID: 7559638
Title: Molecular cloning of a new member of the p21-Cdc42/Rac-activated kinase (PAK) family.
PubMed ID: 7559638
PubMed ID: 9032240
Title: Expression of constitutively active alpha-PAK reveals effects of the kinase on actin and focal complexes.
PubMed ID: 9032240
PubMed ID: 9601050
Title: Delineation of the Cdc42/Rac-binding domain of p21-activated kinase.
PubMed ID: 9601050
DOI: 10.1021/bi980140+
PubMed ID: 9774440
Title: Differential effects of PAK1-activating mutations reveal activity-dependent and -independent effects on cytoskeletal regulation.
PubMed ID: 9774440
PubMed ID: 9528787
Title: A conserved negative regulatory region in alphaPAK: inhibition of PAK kinases reveals their morphological roles downstream of Cdc42 and Rac1.
PubMed ID: 9528787
PubMed ID: 11278486
Title: The mechanism of PAK activation. Autophosphorylation events in both regulatory and kinase domains control activity.
PubMed ID: 11278486
PubMed ID: 12876277
Title: PAK1 phosphorylation of MEK1 regulates fibronectin-stimulated MAPK activation.
PubMed ID: 12876277
PubMed ID: 14707132
Title: Characterization of OSR1, a member of the mammalian Ste20p/germinal center kinase subfamily.
PubMed ID: 14707132
PubMed ID: 19029984
Title: Modification of mineralocorticoid receptor function by Rac1 GTPase: implication in proteinuric kidney disease.
PubMed ID: 19029984
DOI: 10.1038/nm.1879
PubMed ID: 22669945
Title: Synapses of amphids defective (SAD-A) kinase promotes glucose-stimulated insulin secretion through activation of p21-activated kinase (PAK1) in pancreatic beta-Cells.
PubMed ID: 22669945
PubMed ID: 22673903
Title: Quantitative maps of protein phosphorylation sites across 14 different rat organs and tissues.
PubMed ID: 22673903
DOI: 10.1038/ncomms1871
PubMed ID: 24089484
Title: Shank3 deficiency induces NMDA receptor hypofunction via an actin-dependent mechanism.
PubMed ID: 24089484
PubMed ID: 25284783
Title: GIT1 and betaPIX are essential for GABA(A) receptor synaptic stability and inhibitory neurotransmission.
PubMed ID: 25284783
PubMed ID: 10802735
Title: Structure of Cdc42 bound to the GTPase binding domain of PAK.
PubMed ID: 10802735
DOI: 10.1038/75158
Sequence Information:
- Length: 544
- Mass: 60578
- Checksum: 93BE32D8222F5B7B
- Sequence:
MSNNGLDVQD KPPAPPMRNT STMIGAGSKD PGTLNHGSKP LPPNPEEKKK KDRFYRSILA GDKTNKKKEK ERPEISLPSD FEHTIHVGFD AVTGEFTGMP EQWARLLQTS NITKSEQKKN PQAVLDVLEF YNSKKTSNSQ KYMSFTDKSA EDYNSSNTLN VKTVSETPAV PPVSEDEDDD DDATPPPVIA PRPEHTKSVY TRSVIEPLPV TPTRDVATSP ISPTENNTTP PDALTRNTEK QKKKPKMSDE EILEKLRSIV SVGDPKKKYT RFEKIGQGAS GTVYTAMDVA TGQEVAIKQM NLQQQPKKEL IINEILVMRE NKNPNIVNYL DSYLVGDELW VVMEYLAGGS LTDVVTETCM DEGQIAAVCR ECLQALEFLH SNQVIHRDIK SDNILLGMDG SVKLTDFGFC AQITPEQSKR STMVGTPYWM APEVVTRKAY GPKVDIWSLG IMAIEMIEGE PPYLNENPLR ALYLIATNGT PELQNPEKLS AIFRDFLNRC LEMDVEKRGS AKELLQHQFL KIAKPLSSLT PLIAAAKEAT KNNH
Database document:
This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.