Pak2 | ENSRNOG00000001747 | NCBI 29432

Details for: Pak2

Gene ID: 29432

Symbol: Pak2

Ensembl ID: ENSRNOG00000001747

Description: p21 (RAC1) activated kinase 2

Associated with

Adaptive immune system
(R-RNO-1280218)
Axon guidance
(R-RNO-422475)
C-type lectin receptors (clrs)
(R-RNO-5621481)
Cd28 co-stimulation
(R-RNO-389356)
Cd28 dependent vav1 pathway
(R-RNO-389359)
Cd209 (dc-sign) signaling
(R-RNO-5621575)
Costimulation by the cd28 family
(R-RNO-388841)
Developmental biology
(R-RNO-1266738)
Eph-ephrin signaling
(R-RNO-2682334)
Ephrin signaling
(R-RNO-3928664)
Fc epsilon receptor (fceri) signaling
(R-RNO-2454202)
Fceri mediated mapk activation
(R-RNO-2871796)
Generation of second messenger molecules
(R-RNO-202433)
Immune system
(R-RNO-168256)
Innate immune system
(R-RNO-168249)
Mapk6/mapk4 signaling
(R-RNO-5687128)
Mapk family signaling cascades
(R-RNO-5683057)
Muscle contraction
(R-RNO-397014)
Nervous system development
(R-RNO-9675108)
Rac1 gtpase cycle
(R-RNO-9013149)
Rac2 gtpase cycle
(R-RNO-9013404)
Rhog gtpase cycle
(R-RNO-9013408)
Rho gtpase cycle
(R-RNO-9012999)
Rho gtpase effectors
(R-RNO-195258)
Rho gtpases activate paks
(R-RNO-5627123)
Rhoh gtpase cycle
(R-RNO-9013407)
Rhoq gtpase cycle
(R-RNO-9013406)
Rhou gtpase cycle
(R-RNO-9013420)
Rhov gtpase cycle
(R-RNO-9013424)
Sema3a pak dependent axon repulsion
(R-RNO-399954)
Semaphorin interactions
(R-RNO-373755)
Signaling by receptor tyrosine kinases
(R-RNO-9006934)
Signaling by rho gtpases
(R-RNO-194315)
Signaling by rho gtpases, miro gtpases and rhobtb3
(R-RNO-9716542)
Signaling by vegf
(R-RNO-194138)
Signal transduction
(R-RNO-162582)
Smooth muscle contraction
(R-RNO-445355)
Tcr signaling
(R-RNO-202403)
Vegfa-vegfr2 pathway
(R-RNO-4420097)
Vegfr2 mediated vascular permeability
(R-RNO-5218920)
Adherens junction assembly
(GO:0034333)
Atp binding
(GO:0005524)
Bicellular tight junction assembly
(GO:0070830)
Cardiac muscle hypertrophy
(GO:0003300)
Cell-cell junction
(GO:0005911)
Cellular response to organic cyclic compound
(GO:0071407)
Cellular response to transforming growth factor beta stimulus
(GO:0071560)
Cytoplasm
(GO:0005737)
Cytosol
(GO:0005829)
Dendritic spine development
(GO:0060996)
Glutamatergic synapse
(GO:0098978)
Identical protein binding
(GO:0042802)
Intracellular signal transduction
(GO:0035556)
Localization
(GO:0051179)
Membrane
(GO:0016020)
Negative regulation of apoptotic process
(GO:0043066)
Negative regulation of stress fiber assembly
(GO:0051497)
Nucleus
(GO:0005634)
Perinuclear region of cytoplasm
(GO:0048471)
Phosphorylation
(GO:0016310)
Positive regulation of extrinsic apoptotic signaling pathway
(GO:2001238)
Positive regulation of peptidyl-tyrosine phosphorylation
(GO:0050731)
Postsynaptic density
(GO:0014069)
Protein kinase activity
(GO:0004672)
Protein kinase binding
(GO:0019901)
Protein localization to cell-cell junction
(GO:0150105)
Protein phosphorylation
(GO:0006468)
Protein serine/threonine kinase activity
(GO:0004674)
Protein serine kinase activity
(GO:0106310)
Protein tyrosine kinase activator activity
(GO:0030296)
Regulation of axonogenesis
(GO:0050770)
Regulation of cytoskeleton organization
(GO:0051493)
Regulation of mapk cascade
(GO:0043408)
Secretory granule
(GO:0030141)
Small gtpase binding
(GO:0031267)

Other Information

Proteins

Serine/threonine-protein kinase PAK 2

Genular Protein ID: 2517314577

Symbol: PAK2_RAT

Name: Serine/threonine-protein kinase PAK 2

UniProtKB Accession Codes:

Q64303 Q9QYU0

Database IDs:

Citations:

PubMed ID: 7592896

Title: Identification and molecular cloning of a p21cdc42/rac1-activated serine/threonine kinase that is rapidly activated by thrombin in platelets.

PubMed ID: 7592896

DOI: 10.1074/jbc.270.44.26690

PubMed ID: 16396499

Title: Phosphoproteomic analysis of rat liver by high capacity IMAC and LC-MS/MS.

PubMed ID: 16396499

DOI: 10.1021/pr0503073

PubMed ID: 16641100

Title: Quantitative phosphoproteomics of vasopressin-sensitive renal cells: regulation of aquaporin-2 phosphorylation at two sites.

PubMed ID: 16641100

DOI: 10.1073/pnas.0600895103

PubMed ID: 22673903

Title: Quantitative maps of protein phosphorylation sites across 14 different rat organs and tissues.

PubMed ID: 22673903

DOI: 10.1038/ncomms1871

Sequence Information:

Length: 524
Mass: 57960
Checksum: A3F2FEE81C8D4294
Sequence:

MSDNGELEDK PPAPPVRMSS TIFSTGGKDP LSANHSLKPL PSVPEEKKPR NKIISIFSST 
EKGSKKKEKE RPEISPPSDF EHTIHVGFDA VTGEFTGMPE QWARLLQTSN ITKLEQKKNP 
QAVLDVLKFY DSNTVKQKYL SFTPPEKDGF PSGTPALNTK GSETSAVVTE EDDDDEDAAP 
PVIAPRPDHT KSIYTRSVID PIPAPVGDSN VDSGAKSSDK QKKKAKMTDE EIMEKLRTIV 
SIGDPKKKYT RYEKIGQGAS GTVFTATDVA LGQEVAIKQI NLQKQPKKEL IINEILVMKE 
LKNPNIVNFL DSYLVGDELF VVMEYLAGGS LTDVVTETCM DEAQIAAVCR ECLQALEFLH 
ANQVIHRDIK SDNVLLGMEG SVKLTDFGFC AQITPEQSKR STMVGTPYWM APEVVTRKAY 
GPKVDIWSLG IMAIEMVEGE PPYLNENPLR ALYLIATNGT PELQNPEKLS PIFRDFLNRC 
LEMDVEKRGS AKELLQHPFL KLAKPLSSLT PLILAAKEAM KSNR

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: Pak2

Associated with

Other Information

Identification and molecular cloning of a p21cdc42/rac1-activated serine/threonine kinase that is rapidly activated by thrombin in platelets. PubMed ID: 7592896

Phosphoproteomic analysis of rat liver by high capacity IMAC and LC-MS/MS. PubMed ID: 16396499

Quantitative phosphoproteomics of vasopressin-sensitive renal cells: regulation of aquaporin-2 phosphorylation at two sites. PubMed ID: 16641100

Quantitative maps of protein phosphorylation sites across 14 different rat organs and tissues. PubMed ID: 22673903

Database document:

PubMed ID: 7592896

PubMed ID: 16396499

PubMed ID: 16641100

PubMed ID: 22673903