Details for: Slc26a4

Gene ID: 29440

Symbol: Slc26a4

Ensembl ID: ENSRNOG00000058692

Description: solute carrier family 26 member 4

Associated with

Other Information

Genular Protein ID: 3930869853

Symbol: S26A4_RAT

Name: Pendrin

UniProtKB Accession Codes:

Database IDs:

Citations:

PubMed ID: 10449762

Title: Expression pattern of the mouse ortholog of the Pendred's syndrome gene (Pds) suggests a key role for pendrin in the inner ear.

PubMed ID: 10449762

DOI: 10.1073/pnas.96.17.9727

PubMed ID: 11208611

Title: Pendrin: an apical Cl-/OH-/HCO3- exchanger in the kidney cortex.

PubMed ID: 11208611

DOI: 10.1152/ajprenal.2001.280.2.f356

PubMed ID: 11274445

Title: Pendrin, encoded by the Pendred syndrome gene, resides in the apical region of renal intercalated cells and mediates bicarbonate secretion.

PubMed ID: 11274445

DOI: 10.1073/pnas.071516798

PubMed ID: 12107249

Title: Pendrin is an iodide-specific apical porter responsible for iodide efflux from thyroid cells.

PubMed ID: 12107249

DOI: 10.1210/jcem.87.7.8679

PubMed ID: 26791486

Title: Iodide excess regulates its own efflux: a possible involvement of pendrin.

PubMed ID: 26791486

DOI: 10.1152/ajpcell.00210.2015

Sequence Information:

  • Length: 780
  • Mass: 85715
  • Checksum: DA0CDB7496B8D535
  • Sequence:
  • MAARDRRSEP PQLAEYSCSY AVSRPVYSEL AFQQQRERRL PERRTLRDSL ARSCSCSRKR 
    AFGALKALLP ILDWLPKYRV KEWLLSDIIS GVSTGLVGTL QGMAYALLAA VPVQYGLYSA 
    FFPILTYFVF GTSRHISVGP FPVVSLMVGS VVLSMAPDDH FLVPSGNGST LNTTTLDTGT 
    RDAARVLLAS TLTLLVGIIQ LVFGGLQIGF IVRYLADPLV GGFTTAAAFQ VLVSQLKIVL 
    NVSTKNYNGV LSIIYTLIEI FQNIGDTNIA DFIAGLLTII VCMAVKELND RFKHKIPVPI 
    PIEVIVTIIA TAISYGANLE ANYNAGIVKS IPSGFLPPVL PSVGLFSDML AASFSIAVVA 
    YAIAVSVGKV YATKHDYIID GNQEFIAFGI SNVFSGFFSC FVATTALSRT AVQESTGGKT 
    QVAGLISAVI VMVAIVALGK LLEPLQKSVL AAVVIANLKG MFMQVCDVPR LWKQNKTDAV 
    IWVFTCIMSI ILGLDLGLLA GLLFGLLTVV LRVQFPSWNG LGSVPSTDIY KSITHYKNLE 
    EPEGVKILRF SSPIFYGNVD GFKKCVKSTV GFDAIRVYNK RLKALRRIQK LIKKGQLRAT 
    KNGIISDVGS SNNAFEPDED VEEPEELDIP TKEIEIQVDW NSELPVKVNV PKVPIHSLVL 
    DCGAVSFLDV VGVRSLRMIV KEFQRIDVNV YFALLQDDVL EKMEQCGFFD DNIRKDRFFL 
    TVHDAILYLQ NQAKSREGQD SLLETITLIQ DCKDPLELME AEINEEELDV QDEAMRRLAS

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.