Details for: Ahcy

Gene ID: 29443

Symbol: Ahcy

Ensembl ID: ENSRNOG00000017777

Description: adenosylhomocysteinase

Associated with

Other Information

Genular Protein ID: 2102797189

Symbol: SAHH_RAT

Name: Adenosylhomocysteinase

UniProtKB Accession Codes:

Database IDs:

Citations:

PubMed ID: 3027698

Title: Amino acid sequence of S-adenosyl-L-homocysteine hydrolase from rat liver as derived from the cDNA sequence.

PubMed ID: 3027698

DOI: 10.1073/pnas.84.3.719

PubMed ID: 7744082

Title: The gene and pseudogenes of rat S-adenosyl-L-homocysteine hydrolase.

PubMed ID: 7744082

DOI: 10.1111/j.1432-1033.1995.tb20500.x

PubMed ID: 3759971

Title: S-adenosylhomocysteinase from rat liver. Amino acid sequences of the peptides containing active site cysteine residues modified by treatment with 5'-p-fluorosulfonylbenzoyladenosine.

PubMed ID: 3759971

DOI: 10.1016/s0021-9258(18)67034-6

PubMed ID: 10387078

Title: Crystal structure of S-adenosylhomocysteine hydrolase from rat liver.

PubMed ID: 10387078

DOI: 10.1021/bi990332k

PubMed ID: 10913437

Title: Effects of site-directed mutagenesis on structure and function of recombinant rat liver S-adenosylhomocysteine hydrolase. Crystal structure of D244E mutant enzyme.

PubMed ID: 10913437

DOI: 10.1074/jbc.m003725200

PubMed ID: 11741948

Title: Inhibition of S-adenosylhomocysteine hydrolase by acyclic sugar adenosine analogue D-eritadenine. Crystal structure of S-adenosylhomocysteine hydrolase complexed with D-eritadenine.

PubMed ID: 11741948

DOI: 10.1074/jbc.m109187200

PubMed ID: 11927587

Title: Catalytic mechanism of S-adenosylhomocysteine hydrolase. Site-directed mutagenesis of Asp-130, Lys-185, Asp-189, and Asn-190.

PubMed ID: 11927587

DOI: 10.1074/jbc.m201116200

Sequence Information:

  • Length: 432
  • Mass: 47538
  • Checksum: 93CA5BED07B4FCDE
  • Sequence:
  • MADKLPYKVA DIGLAAWGRK ALDIAENEMP GLMRMREMYS ASKPLKGARI AGCLHMTVET 
    AVLIETLVAL GAEVRWSSCN IFSTQDHAAA AIAKAGIPVF AWKGETDEEY LWCIEQTLHF 
    KDGPLNMILD DGGDLTNLIH TKHPQLLSGI RGISEETTTG VHNLYKMMAN GILKVPAINV 
    NDSVTKSKFD NLYGCRESLI DGIKRATDVM IAGKVAVVAG YGDVGKGCAQ ALRGFGARVI 
    ITEIDPINAL QAAMEGYEVT TMDEACKEGN IFVTTTGCVD IILGRHFEQM KDDAIVCNIG 
    HFDVEIDVKW LNENAVEKVN IKPQVDRYLL KNGHRIILLA EGRLVNLGCA MGHPSFVMSN 
    SFTNQVMAQI ELWTHPDKYP VGVHFLPKKL DEAVAEAHLG KLNVKLTKLT EKQAQYLGMP 
    INGPFKPDHY RY

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.