Rab7a | ENSRNOG00000012247 | NCBI 29448

Details for: Rab7a

Gene ID: 29448

Symbol: Rab7a

Ensembl ID: ENSRNOG00000012247

Description: RAB7A, member RAS oncogene family

Associated with

Adaptive immune system
(R-RNO-1280218)
Immune system
(R-RNO-168256)
Innate immune system
(R-RNO-168249)
Membrane trafficking
(R-RNO-199991)
Metabolism of proteins
(R-RNO-392499)
Mhc class ii antigen presentation
(R-RNO-2132295)
Neutrophil degranulation
(R-RNO-6798695)
Post-translational protein modification
(R-RNO-597592)
Rab gefs exchange gtp for gdp on rabs
(R-RNO-8876198)
Rab geranylgeranylation
(R-RNO-8873719)
Rab regulation of trafficking
(R-RNO-9007101)
Rac1 gtpase cycle
(R-RNO-9013149)
Rac2 gtpase cycle
(R-RNO-9013404)
Rhod gtpase cycle
(R-RNO-9013405)
Rhof gtpase cycle
(R-RNO-9035034)
Rhog gtpase cycle
(R-RNO-9013408)
Rho gtpase cycle
(R-RNO-9012999)
Rhoh gtpase cycle
(R-RNO-9013407)
Rhoq gtpase cycle
(R-RNO-9013406)
Signaling by rho gtpases
(R-RNO-194315)
Signaling by rho gtpases, miro gtpases and rhobtb3
(R-RNO-9716542)
Signal transduction
(R-RNO-162582)
Tbc/rabgaps
(R-RNO-8854214)
Vesicle-mediated transport
(R-RNO-5653656)
Alveolar lamellar body
(GO:0097208)
Autophagosome assembly
(GO:0000045)
Autophagosome membrane
(GO:0000421)
Bone resorption
(GO:0045453)
Cytoplasm
(GO:0005737)
Cytosol
(GO:0005829)
Early endosome to late endosome transport
(GO:0045022)
Endosome
(GO:0005768)
Endosome membrane
(GO:0010008)
Endosome to lysosome transport
(GO:0008333)
Endosome to plasma membrane protein transport
(GO:0099638)
Epidermal growth factor catabolic process
(GO:0007174)
Establishment of vesicle localization
(GO:0051650)
Exocytic vesicle
(GO:0070382)
Gdp binding
(GO:0019003)
Golgi apparatus
(GO:0005794)
G protein activity
(GO:0003925)
Gtpase activity
(GO:0003924)
Gtp binding
(GO:0005525)
Intracellular transport
(GO:0046907)
Late endosome
(GO:0005770)
Late endosome membrane
(GO:0031902)
Lipid catabolic process
(GO:0016042)
Lipid droplet
(GO:0005811)
Lipophagy
(GO:0061724)
Lysosomal membrane
(GO:0005765)
Lysosome
(GO:0005764)
Melanosome membrane
(GO:0033162)
Mitochondrial membrane
(GO:0031966)
Mitochondrion
(GO:0005739)
Negative regulation of exosomal secretion
(GO:1903542)
Phagocytic vesicle
(GO:0045335)
Phagocytic vesicle membrane
(GO:0030670)
Phagophore assembly site membrane
(GO:0034045)
Phagosome-lysosome fusion
(GO:0090385)
Phagosome acidification
(GO:0090383)
Positive regulation of exosomal secretion
(GO:1903543)
Positive regulation of protein catabolic process
(GO:0045732)
Positive regulation of viral process
(GO:0048524)
Protein binding
(GO:0005515)
Protein targeting to lysosome
(GO:0006622)
Protein to membrane docking
(GO:0022615)
Response to bacterium
(GO:0009617)
Retrograde transport, endosome to golgi
(GO:0042147)
Retromer complex
(GO:0030904)
Retromer complex binding
(GO:1905394)
Small gtpase binding
(GO:0031267)
Synaptic vesicle membrane
(GO:0030672)
Terminal bouton
(GO:0043195)
Viral release from host cell
(GO:0019076)

Other Information

Proteins

Ras-related protein Rab-7a

Genular Protein ID: 1633098115

Symbol: RAB7A_RAT

Name: Ras-related protein Rab-7a

UniProtKB Accession Codes:

P09527 Q4AEF6

Database IDs:

Citations:

PubMed ID: 3057452

Title: A new member of the ras gene superfamily identified in a rat liver cell line.

PubMed ID: 3057452

DOI: 10.1093/nar/16.21.9979

PubMed ID: 15978772

Title: Fine mapping of radiation susceptibility and gene expression analysis of LEC congenic rat lines.

PubMed ID: 15978772

DOI: 10.1016/j.ygeno.2005.05.007

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 16040606

Title: Possible role of direct Rac1-Rab7 interaction in ruffled border formation of osteoclasts.

PubMed ID: 16040606

DOI: 10.1074/jbc.m414213200

PubMed ID: 16306406

Title: The small GTPase Rab7 controls the endosomal trafficking and neuritogenic signaling of the nerve growth factor receptor TrkA.

PubMed ID: 16306406

DOI: 10.1523/jneurosci.2029-05.2005

PubMed ID: 18756270

Title: Structures of RabGGTase-substrate/product complexes provide insights into the evolution of protein prenylation.

PubMed ID: 18756270

DOI: 10.1038/emboj.2008.164

PubMed ID: 22673903

Title: Quantitative maps of protein phosphorylation sites across 14 different rat organs and tissues.

PubMed ID: 22673903

DOI: 10.1038/ncomms1871

PubMed ID: 15186776

Title: Structure of the Rab7:REP-1 complex: insights into the mechanism of Rab prenylation and choroideremia disease.

PubMed ID: 15186776

DOI: 10.1016/j.cell.2004.05.017

Sequence Information:

Length: 207
Mass: 23504
Checksum: A2AF33B02F672971
Sequence:

MTSRKKVLLK VIILGDSGVG KTSLMNQYVN KKFSNQYKAT IGADFLTKEV MVDDRLVTMQ 
IWDTAGQERF QSLGVAFYRG ADCCVLVFDV TAPNTFKTLD SWRDEFLIQA SPRDPENFPF 
VVLGNKIDLE NRQVATKRAQ AWCYSKNNIP YFETSAKEAI NVEQAFQTIA RNALKQETEV 
ELYNEFPEPI KLDKNERAKA SAESCSC

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: Rab7a

Associated with

Other Information

A new member of the ras gene superfamily identified in a rat liver cell line. PubMed ID: 3057452

Fine mapping of radiation susceptibility and gene expression analysis of LEC congenic rat lines. PubMed ID: 15978772

The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). PubMed ID: 15489334

Possible role of direct Rac1-Rab7 interaction in ruffled border formation of osteoclasts. PubMed ID: 16040606

The small GTPase Rab7 controls the endosomal trafficking and neuritogenic signaling of the nerve growth factor receptor TrkA. PubMed ID: 16306406

Structures of RabGGTase-substrate/product complexes provide insights into the evolution of protein prenylation. PubMed ID: 18756270

Quantitative maps of protein phosphorylation sites across 14 different rat organs and tissues. PubMed ID: 22673903

Structure of the Rab7:REP-1 complex: insights into the mechanism of Rab prenylation and choroideremia disease. PubMed ID: 15186776