Tesk1 | ENSRNOG00000053729 | NCBI 29460

Details for: Tesk1

Gene ID: 29460

Symbol: Tesk1

Ensembl ID: ENSRNOG00000053729

Description: testis associated actin remodelling kinase 1

Associated with

Cell-cell communication
(R-RNO-1500931)
Cell-extracellular matrix interactions
(R-RNO-446353)
Cell junction organization
(R-RNO-446728)
Regulation of cytoskeletal remodeling and cell spreading by ipp complex components
(R-RNO-446388)
Actin cytoskeleton organization
(GO:0030036)
Atp binding
(GO:0005524)
Centrosome
(GO:0005813)
Cytoplasm
(GO:0005737)
Cytoplasmic vesicle
(GO:0031410)
Establishment of vesicle localization
(GO:0051650)
Lamellipodium
(GO:0030027)
Metal ion binding
(GO:0046872)
Negative regulation of cilium assembly
(GO:1902018)
Negative regulation of phosphorylation
(GO:0042326)
Negative regulation of protein autophosphorylation
(GO:0031953)
Nucleus
(GO:0005634)
Perinuclear region of cytoplasm
(GO:0048471)
Phosphorylation
(GO:0016310)
Podocyte cell migration
(GO:0090521)
Positive regulation of protein localization to nucleus
(GO:1900182)
Positive regulation of protein phosphorylation
(GO:0001934)
Positive regulation of stress fiber assembly
(GO:0051496)
Positive regulation of substrate adhesion-dependent cell spreading
(GO:1900026)
Protein binding
(GO:0005515)
Protein kinase activity
(GO:0004672)
Protein kinase binding
(GO:0019901)
Protein serine/threonine/tyrosine kinase activity
(GO:0004712)
Protein serine/threonine kinase activity
(GO:0004674)
Protein serine kinase activity
(GO:0106310)
Protein tyrosine kinase activity
(GO:0004713)
Regulation of actin cytoskeleton organization
(GO:0032956)
Regulation of protein localization
(GO:0032880)
Spermatogenesis
(GO:0007283)

Other Information

Proteins

Dual specificity testis-specific protein kinase 1

Genular Protein ID: 1816301100

Symbol: TESK1_RAT

Name: Dual specificity testis-specific protein kinase 1

UniProtKB Accession Codes:

Q63572

Database IDs:

Citations:

PubMed ID: 8537404

Title: Identification and characterization of a novel protein kinase, TESK1, specifically expressed in testicular germ cells.

PubMed ID: 8537404

DOI: 10.1074/jbc.270.52.31331

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 10207045

Title: Dual specificity protein kinase activity of testis-specific protein kinase 1 and its regulation by autophosphorylation of serine-215 within the activation loop.

PubMed ID: 10207045

DOI: 10.1074/jbc.274.17.12171

PubMed ID: 11555644

Title: Binding of 14-3-3beta regulates the kinase activity and subcellular localization of testicular protein kinase 1.

PubMed ID: 11555644

DOI: 10.1074/jbc.m104620200

PubMed ID: 15817463

Title: Actopaxin interacts with TESK1 to regulate cell spreading on fibronectin.

PubMed ID: 15817463

DOI: 10.1074/jbc.m500752200

PubMed ID: 17974561

Title: Tesk1 interacts with Spry2 to abrogate its inhibition of ERK phosphorylation downstream of receptor tyrosine kinase signaling.

PubMed ID: 17974561

DOI: 10.1074/jbc.m705457200

PubMed ID: 18216281

Title: Spred1 and TESK1--two new interaction partners of the kinase MARKK/TAO1 that link the microtubule and actin cytoskeleton.

PubMed ID: 18216281

DOI: 10.1091/mbc.e07-07-0730

PubMed ID: 22302232

Title: Spatiotemporal expression of testicular protein kinase 1 after rat sciatic nerve injury.

PubMed ID: 22302232

DOI: 10.1007/s12031-012-9712-x

Sequence Information:

Length: 628
Mass: 67988
Checksum: F05F67FBD934B9AD
Sequence:

MAGERPPLRG PGPGETPVEG PGGAGGGPGR GRPSSYRALR SAVSSLARVD DFDCAEKIGA 
GFFSEVYKVR HRQSGQVMVL KMNKLPSNRS NTLREVQLMN RLRHPNILRF MGVCVHQGQL 
HALTEYMNGG TLEQLLSSPE PLSWPVRLHL ALDIAQGLRY LHAKGVFHRD LTSKNCLVRR 
EDGGFTAVVG DFGLAEKIPV YREGARKEPL AVVGSPYWMA PEVLRGELYD EKADVFAFGI 
VLCELIARVP ADPDYLPRTE DFGLDVPAFR TLVGNDCPLP FLLLAIHCCS MEPSARAPFT 
EITQHLEQIL EQLPEPTPLA KMPLAKAPLT YNQGSVPRGG PSATLPRSDP RLSRSRSDLF 
LPPSPESPPS WGDNLTRVNP FSLREDLRGG KIKLLDTPCK PATPLPLVPP SPLTSTQLPL 
VASPESLVQP ETPVRRCRSL PSSPELPRRM ETALPGPGPS PVGPSTEERM DCEGSSPEPE 
PPGPAPQLPL AVATDNFIST CSSASQPWSA RPGPSLNNNP PAVVVNSPQG WAREPWNRAQ 
HSLPRAAALE RTEPSPPPSA PREQEEGLPC PGCCLSPFSF GFLSMCPRPT PAVARYRNLN 
CEAGSLLCHR GHHAKPPTPS LQLPGARS

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: Tesk1

Associated with

Other Information

Identification and characterization of a novel protein kinase, TESK1, specifically expressed in testicular germ cells. PubMed ID: 8537404

The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). PubMed ID: 15489334

Dual specificity protein kinase activity of testis-specific protein kinase 1 and its regulation by autophosphorylation of serine-215 within the activation loop. PubMed ID: 10207045

Binding of 14-3-3beta regulates the kinase activity and subcellular localization of testicular protein kinase 1. PubMed ID: 11555644

Actopaxin interacts with TESK1 to regulate cell spreading on fibronectin. PubMed ID: 15817463

Tesk1 interacts with Spry2 to abrogate its inhibition of ERK phosphorylation downstream of receptor tyrosine kinase signaling. PubMed ID: 17974561

Spred1 and TESK1--two new interaction partners of the kinase MARKK/TAO1 that link the microtubule and actin cytoskeleton. PubMed ID: 18216281

Spatiotemporal expression of testicular protein kinase 1 after rat sciatic nerve injury. PubMed ID: 22302232